Information System of Masaryk University 

Course Information

C6770 NMR Spectroscopy of Biomolecules

Faculty of Science
Spring 2007

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Recommended Type of Completion: zk (examination). Alternate Types of Completion: k (colloquium).

Teacher(s)

doc. RNDr. Radovan Fiala, CSc. (lecturer)
Mgr. Jaromír Toušek, Dr. (lecturer)
doc. Mgr. Lukáš Žídek, Ph.D. (lecturer)

Supervisor

doc. Mgr. Lukáš Žídek, Ph.D.
National Centre for Biomolecular Research - Faculty of Science
Contact Person: doc. Mgr. Lukáš Žídek, Ph.D.

Timetable

Tue 10:00–11:50 A4-211

Course Enrollment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

Fields of study the course is directly associated with

there are 14 fields of study the course is directly associated with, display

Course objectives

The course will provide introduction to modern NMR techniques which can be applied to extract structural information for small and mid-size biological macromolecules - peptides, proteins, DNA and RNA oligonucleotides. Experimental procedures and computational protocols for determination of three-dimensional structures and dynamics based on NMR data will be discussed.

Syllabus

• 1. NMR as a tool for structure biology 2. Basic NMR Experiments 3. Key to biomolecular NMR: Idea of correlation 4. First step in NMR of proteins 5. Second step in determination of protein structure 6. From spectra to structure 7. Special features of nucleic acid NMR 8. Nucleic acid structure by NMR 9. Molecules are not rigid 10. From relaxation to molecular motions 11. Molecules are not alone 12. Beyond small soluble biomolecules

Literature

• CAVANAGH, John and Wayne J. FAIRBROTHER. Protein NMR Spectroscopy. Principles and Practice. San Diego: Academic Press, 1996. 587 pp. ISBN 0-12-164490-1. info

Assessment methods (in Czech)

Oral examination based on discussion of a project solved by the student.

Language in which the course is taught

English

Follow-Up Courses

• C6775 NMR Spectroscopy of Biomolecules
• C7995 Advanced Methods of Biomolecular NMR

Further Comments

The course is taught annually.

Teacher's information

http://www.ncbr.chemi.muni.cz/~lzidek/C6770.html

The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2000, Spring 2001, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2008, Spring 2009, Spring 2010, Spring 2011, spring 2012, spring 2012 - acreditation, spring 2013, spring 2014.

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• Enrollment Statistics (Spring 2007, recent)
  
• Permalink: https://is.muni.cz/course/sci/spring2007/C6770

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