F8510 Physics of biopolymers

Faculty of Science
Spring 2014
Extent and Intensity
2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
Teacher(s)
Mgr. Naděžda Špačková, Ph.D. (lecturer)
Guaranteed by
prof. RNDr. Josef Humlíček, CSc.
Department of Condensed Matter Physics – Physics Section – Faculty of Science
Contact Person: doc. Mgr. Karel Kubíček, PhD.
Supplier department: Department of Condensed Matter Physics – Physics Section – Faculty of Science
Timetable
Wed 18:00–19:50 F1 6/1014
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The course is focused on description, explanation and understanding of molecular structure, dynamic behavior, and physical properties of biopolymers (including DNA, RNA and proteins).
The main objective of the course is to provide the students with the ability to
- understand biopolymer structure and behavior
- describe and explain fundamental physical properties of biopolymers, which are responsible for their biological function
- apply this knowledge to explanation of environmental effects influencing biopolymers
Syllabus
  • 1. Primary, secondary and tertiary structure of nucleic acids
  • 2. Primary, secondary and tertiary structure of proteins
  • 3. Noncovalent interactions in biopolymers
  • 4. Biopolymer behavior in solution, interactions with ions and ligands
  • 5. Interactions of biopolymers with electromagnetic radiation, spectroskopic methods
  • 6. Diffraction metods, X-ray crystalography
  • 7. Optical properties of biopolymers, linear and circular dichroism
  • 8. Elektric properties of biopolymers
  • 9. Magnetic properties of biopolymers, nuclear magnetic resonance
  • 10. Mechanic properties of biopolymers
  • 11. Theoretical study of biopolymers
Literature
  • S. Neidle, Principles of Nucleic Acid Structure, Academic Press , 2007, 302 p., eISBN: 9780080553528
  • A.V. Finkelstein, O. Ptitsyn, Protein Physics : A Course of Lectures, Academic Press, 2002, 375 p., eISBN: 9780080492186
  • J.N. Israelachvili, Intermolecular and Surface Forces, Academic Press, 2011, 674 p., ISBN: 978-0-12-391927-4
Teaching methods
lectures, class discussion
Assessment methods
oral exam based on specific thematic questions
Language of instruction
Czech
Further Comments
Study Materials
The course is taught annually.
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024.
  • Enrolment Statistics (Spring 2014, recent)
  • Permalink: https://is.muni.cz/course/sci/spring2014/F8510