The goal of physiology is to explain the physical and chemical factors that are responsible for the origin, development, and progression of the life. In human physiology, we attempt to explain the specific characteristics and mechanisms of the human body that make it a living being.
In the course of lectures, student gets hold of knowledge of general and systematic human physiology, learns how to analyse special text and how to find relevant and substantive information, to cover basic relationships and regulations in living systems, including basic knowledge of biocybernetics. After finishing normal physiology course, the student is acquainted with main basic experimental methods used in physiology, mainly by a form of practices. During practices, the student must get acquainted with current examination methods, used in everyday clinical physiology (e.g. electrocardiography, electroencephalography, electromyography, spirometry), including exercise tests (ergometry). Students must make conclusions from their own measured values.
The main outcome of normal physiology studies is therefore to teach the students not only the review of physiology, but also to enable them to get practical skills and support critical scientific way of thinking.
Syllabus
Structural and functional organisation of the body.
Metabolism. Water and solutes.Cellular contacts and signalling.Cell membranes. Nervous and muscular activity.Internal environment (homeostasis). Physiology of the heart. Conduction system.Cardiac electrophysiology.Electrocardiography. Arrhythmias.Electromechanical coupling.Cardiac mechanics. Heart cycle. Heart failure. Examination of cardiovascular system, cardiol. examination techniques.Rheology of the blood.Coronary circulation. Coronary heart disease.Microcirculation.Regulation of blood flow.Regional circulation (pulmonary, cerebral).Regional circulation (splanchnic, skin, muscle).Regional circulation (renal, fetal).Regulation of blood circulation, of blood pressure.Variability of circulatory parameters.Arterial hypertension.Circulatory failure.
Physiology of blood. Blood clotting.Blood types (groups).Plasma proteins.Immune system.
Literature
Physiology. Edited by Linda S. Costanzo. 4th ed. Philadelphia: Lippincott Williams & Wilkins, 2007. xi, 334 p. ISBN 0781773113. info
SILBERNAGL, Stefan and Agamemnon DESPOPOULOS. Atlas fyziologie člověka. 6. přeprac. vyd. Praha: Grada, 2004. xiii, 435. ISBN 80-247-0630-X. info
TROJAN, Stanislav and Miloš LANGMEIER. Slovníček lékařské fyziologie. 2. dopl. vyd. Praha: Galén, 2006. 141 s. ISBN 80-7262-375-3. info
GUYTON, Arthur C. Textbook of medical physiology. Edited by John E. Hall. 11th ed. Philadelphia: Elsevier Saunders, 2006. xxxv, 1116. ISBN 0-7216-0240-1. info
GANONG, William F. Přehled lékařské fyziologie. 20. vyd. Praha: Galén, 2005. xx, 890 s. ISBN 80-7262-311-7. info
GANONG, William F. Review of medical physiology. 22nd ed. New York: Lange Medical Books/McGraw-Hill, 2005. xii, 912 s. ISBN 0-07-144040-2. info
COSTANZO, Linda S. Physiology. 3rd ed. Philadelphia: Saunders Elsevier, 2006. xi, 490 p. ISBN 1-4160-2320-8. info
TROJAN, Stanislav. Lékařská fyziologie. 4. přeprac. a dopl. vyd. Praha: Grada, 2003. 771 s. ISBN 80-247-0512-5. info
SILBERNAGL, Stefan and Agamemnon DESPOPOULOS. Color atlas of physiology. 6th ed., completely rev. and. New York: Thieme, 2009. xiii, 441. ISBN 978-3-13-545006. info
HELLER, Jiří. Poznámky k přednáškám z fysiologie. Vyd. 1. Jinočany: H & H, 1993. 325 s. ISBN 80-85787-16-4. info
BRAVENÝ, Pavel. Poznámky k přednáškám z fysiologie. 2., přeprac. vyd. Jinočany: H & H, 1992. 281 s. ISBN 80-85467-60-7. info
Assessment methods
lectures
Further comments (probably available only in Czech)
Information on completion of the course: Kdo umí - umí, kdo neumí - jde na opravný termín.
The course is taught: every week.