ZLPF0521p Pathological Physiology I - lecture

Faculty of Medicine
Autumn 2010
Extent and Intensity
2/0/0. 0 credit(s). Type of Completion: -.
prof. MUDr. Lydie Izakovičová Hollá, Ph.D. (lecturer)
prof. MUDr. Kateřina Kaňková, Ph.D. (lecturer)
prof. MUDr. Anna Vašků, CSc. (lecturer)
Věra Ježková (assistant)
Guaranteed by
prof. MUDr. Lydie Izakovičová Hollá, Ph.D.
Department of Pathophysiology - Theoretical Departments - Faculty of Medicine
Contact Person: prof. MUDr. Anna Vašků, CSc.
Thu 13:20–15:00 N03901
Prerequisites (in Czech)
ZLFY0422p Physiology II - lecture && ZLBC041p Biochemistry II -lec. && ZLAN0333p Anatomy III - lect. && ZLHE0322p Hist.and Embryol.II-lect. && ( ZLLT0222s Bas.Med.Terminology II-sem. || ZLLT0222p Bas. Med. Terminology -l ) && ZLET021p Ethics in Dent.-lect. && ZC041 Handling chemical substances
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The objective of the theoretical part of the course is to provide complex information on etiology, pathogenesis and morphological characteristics of diseases. Basic knowledge of the origin and dynamics of the development of pathological states and their morphological correlates will be acquired through lectures and study of the prepared professional text.
  • Pathophysiology: an integrating medical speciality. Aetiology and pathogenesis of diseases.
  • Inflammation,basic mechanisms, its role in the organism and main types of cells and mediators participating in the inflammation.
  • Control of the cell cycle, malignant transformation of a cell. Interaction of tumour and the organism.
  • Regeneration, wound healing.
  • General reaction of the organism to damage - fever, pain and changes by which the inflammation manifests in the organism.
  • Bank holiday
  • Volume and pressure oveload: systolic and diastolic dysfunction of the heart. Heart failure.
  • Ischemic heart disease, myocardial infarction.
  • Pathophysiology of gas exchange in the lungs. Ventilation control.
  • Lung diseases.
  • Kidney as a regulatory organ. Glomerular and tubular diseases.
  • Acute and chronic renal failure.
  • General adaptation syndrome.
  • Reserved topic.
  • NEČAS, Emanuel. Patologická fyziologie orgánových systémů. 1. vyd. Praha: Karolinum, 2003. s. 381-760. ISBN 9788024606743. info
  • NEČAS, Emanuel a spol. Obecná patologická fyziologie. 1. vyd. Praha: Karolinum, 2000. 377 pp. ISBN 80-246-0051-X. info
  • NEČAS, Emanuel. Patologická fyziologie orgánových systémů. 1. vyd. Praha: Karolinum, 2003. 379 s. ISBN 9788024606750. info
  • KAŇKOVÁ, Kateřina. Vybrané kapitoly z patologické fyziologie: Poruchy metabolizmu a výživy. 1. vydání. Brno: Masarykova univerzita v Brně, 2005. 59 pp. ISBN 80-210-3670-2. info
  • PORTH, Carol Mattson. Essentials of Pathophysiology: concepts of altered health states. 2007th ed. United States of America: Williams and Wilkins, 2007. 1147 pp. 2nd edition. ISBN 0-7817-7087-4. info
  • Essentials of pathophysiology. Edited by Chris E. Kaufman - Patrick A. McKee. 1st ed. Boston: Little, Brown and Company, 1996. xvi, 799 s. ISBN 0-316-48405-9. info
Teaching methods
Assessment methods
Oral examination.
Language of instruction
Further Comments
The course is taught each semester.
The course is also listed under the following terms Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2011, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, Autumn 2017, autumn 2018, autumn 2019, autumn 2020, autumn 2021.
  • Enrolment Statistics (Autumn 2010, recent)
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