VSBI0222p Biology II - lecture

Faculty of Medicine
Spring 2014
Extent and Intensity
1/0. 4 credit(s). Recommended Type of Completion: zk (examination). Other types of completion: RZk (examination).
prof. Ing. Petr Dvořák, CSc. (lecturer)
prof. MUDr. Marie Kopecká, CSc. (lecturer)
doc. Mgr. Lumír Krejčí, Ph.D. (lecturer)
Mgr. Pavel Krejčí, Ph.D. (lecturer)
Mgr. Vladimír Rotrekl, Ph.D. (lecturer)
doc. MUDr. Iva Slaninová, Ph.D. (lecturer)
prof. MUDr. Augustin Svoboda, CSc., dr. h.c. (lecturer)
prof. MUDr. David Šmajs, Ph.D. (lecturer)
Mgr. Stjepan Uldrijan, CSc. (lecturer)
doc. Yuh-Man Wadeley, Doctor of Philosophy (lecturer)
Mgr. Hana Hříbková (seminar tutor)
Mgr. Kateřina Vopěnková, Ph.D. (seminar tutor)
Jana Růžičková (assistant)
Eva Skalová (assistant)
Mgr. Martina Vráblíková (assistant)
Guaranteed by
prof. Ing. Petr Dvořák, CSc.
Department of Biology - Theoretical Departments - Faculty of Medicine
Contact Person: Mgr. Kateřina Vopěnková, Ph.D.
Supplier department: Department of Biology - Theoretical Departments - Faculty of Medicine
Mon 8:30–9:20 B22/116 aula
  • Timetable of Seminar Groups:
VSBI0222p/VLA: Wed 15:00–15:50 B11/234
Prerequisites (in Czech)
VSBI0121c Biology I -pract. && ZC011 Handling chemical substances
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
After completion of the course student: understands elementary cellular processes and processes taking place during development of a human body; comprehends the complexity of intercellular communication and mutual regulation of individual cells in a multicellular organism; is able to deduce and explain the difference between healthy and pathologically-working cell; is able to express basic coherence between malfunction in cellular processes and development of diseases, especially hereditary diseases, cancers or developmental defects; can explain and justify action of some therapeutics with emphasis on modern medicine. Student is also able to apply this knowledge and skills in other subject, especially physiology, pathophysiology and human genetics.
  • Week 1: 17.-21.2.
  • Basic principles and molecular mechanisms regulating early development of mammals - physiology and pathology
  • Week 2: 24.-28.2.
  • Biology and use of stem cells in disease modelling and cell therapy
  • Week 3: 3.-7.3.
  • Growth factors and signal transduction in development and disease
  • Week 4: 10.-14.3.
  • Cell differentiation and tissue engineering
  • Week 5: 17.-21.3.
  • Introduction to cancer biology
  • Week 6: 24.-28.3.
  • Oncogenes and oncoviruses in cancer transformation
  • Week 7: 31.3.-4.4.
  • Tumour suppressor genes - implications for diagnostics and
  • Week 8: 7.-11.4.
  • Paradigm of cancer stem cells
  • Week 9: 14.-18.4.
  • Molecular principle of genetically determined diseases
  • Week 10: 21.-25.4.
  • Objectives and strategies of molecular therapy
  • Week 11: 28.4.-2.5.
  • Genomics and other omics in current biomedicine
  • Week 12: 5.-9.5.
  • Bioinformatics in medicine - from molecules to populations
  • Week 13: 12.-16.5.
  • Milestones in biological sciences in context with advances in clinical medicine
  • Week 14: 19.-23.5.
  • Advances in molecular, cell or developmental biology with regard to biomedicine - „Breakthrough of the year 2013“
    recommended literature
  • ALBERTS, Bruce. Základy buněčné biologie : úvod do molekulární biologie buňky. Translated by Arnošt Kotyk. 2. vyd. Ústí nad Labem: Espero Publishing, 2004. xxvi, 630. ISBN 8090290620. info
  • Essential cell biology. Edited by Bruce Alberts. 3rd ed. New York: Garland Science, 2009. 1 v. ISBN 9780815341307. info
  • CAMPBELL, Neil A. Biologie. Edited by Jane B. Reece. Vyd. 1. Brno: Computer Press, 2006. xxxiv, 133. ISBN 8025111784. info
  • CAMPBELL, Neil A. Biology. Edited by Jane B. Reece. 7th ed. San Francisco: Pearson/Benjamin Cummings, 2005. xl, 1231. ISBN 080537146X. info
  • SNUSTAD, D. Peter, Michael J. SIMMONS, Jiřina RELICHOVÁ, Jiří DOŠKAŘ, Jiří FAJKUS, Petr HOŘÍN, Aleš KNOLL, Petr KUGLÍK, Jan ŠMARDA, Jana ŠMARDOVÁ, Renata VESELSKÁ and Boris VYSKOT. Genetika (Principles of Genetics). 1st ed. Brno: Masarykova univerzita, 2009. 894 pp. Učebnice. ISBN 978-80-210-4852-2. URL info
  • SNUSTAD, D. Peter and Michael J. SIMMONS. Principles of genetics. 5th ed. Hoboken: John Wiley & Sons, Inc, 2009. xix, 823. ISBN 9780470388259. info
  • PRITCHARD, D. J. and Bruce R. KORF. Základy lékařské genetiky. první české vydání. Praha: Galén, 2007. 182 stran. ISBN 9788072624492. info
  • HARDIN, Jeff, Gregory BERTONI and Lewis J. KLEINSMITH. Becker's world of the cell. 8th ed. Boston: Benjamin Cummings, 2012. xxviii, 79. ISBN 9780321709783. info
  • JANISCH, Roman. Overview of General Biology. 2. rozšířené. Brno: Masarykova univerzita, 2010. 91 pp. ISBN 978-80-210-5187-4. info
  • LODISH, Harvey F. Molecular cell biology. 6th ed. New York, N.Y.: W.H. Freeman and Company, 2008. xxxvii, 11. ISBN 9780716776017. info
  • POLLARD, Thomas D., William C. EARNSHAW and Jennifer LIPPINCOTT-SCHWARTZ. Cell biology. Illustrated by Graham T. Johnson. 2nd ed. Philadelphia, Pa.: Saunders/Elsevier, 2008. xix, 905. ISBN 9780808923527. info
  • WEINBERG, Robert A. The biology of cancer. Second edition. London: Garland Science, 2013. xx, 876. ISBN 9780815345282. info
  • WOLPERT, Lewis. Principles of development. 2nd ed. Oxford: Oxford University Press, 2002. xxv, 542. ISBN 0198792913. info
Teaching methods
Assessment methods
Lecture attendance is optional. Subject is completed with a written examination test, based on knowledge of all topics from both semesters (lectures, seminars, practices). The exam test contains 100 questions with 1 correct answer. For successful passing the exam, minimum 66 points out of 200 are needed.
Requirements for attendance at the exam: successful passing of the autumn semester’s lecture (VSBI0121p), seminar (VSBI0121s) and practice (VSBI0121c), and spring semester’s practice (VSBI0222c). Students have to bring their valid ICIS card to prove their identity at the exam. For more information on the test see: https://is.muni.cz/auth/el/1411/podzim2013/VSBI0121p/op/Biology_Exam_information_and_instructions_2013_2014.pdf
Language of instruction
Further Comments
Study Materials
The course is taught annually.
Listed among pre-requisites of other courses

Zobrazit další předměty

The course is also listed under the following terms Spring 2000, Spring 2001, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, Spring 2013, Spring 2015, Spring 2016.
  • Enrolment Statistics (Spring 2014, recent)
  • Permalink: https://is.muni.cz/course/med/spring2014/VSBI0222p