aZLBI0222p Biology II - lecture

Faculty of Medicine
Spring 2017
Extent and Intensity
1/0. 3 credit(s). Type of Completion: zk (examination).
Teacher(s)
Mgr. Kateřina Cetkovská, Ph.D. (lecturer)
prof. Ing. Petr Dvořák, CSc. (lecturer)
doc. Mgr. Lumír Krejčí, Ph.D. (lecturer)
RNDr. Pavel Krejčí, Ph.D. (lecturer)
Mgr. Vladimír Rotrekl, Ph.D. (lecturer)
doc. MUDr. Iva Slaninová, Ph.D. (lecturer)
prof. MUDr. David Šmajs, Ph.D. (lecturer)
RNDr. Mário Špírek, PhD. (lecturer)
Mgr. Stjepan Uldrijan, CSc. (lecturer)
Mgr. Kateřina Vopěnková, Ph.D. (lecturer)
Jana Růžičková (assistant)
Mgr. Kateřina Straková, Ph.D. (assistant)
Mgr. Martina Vráblíková (assistant)
Guaranteed by
prof. Ing. Petr Dvořák, CSc.
Department of Biology - Theoretical Departments - Faculty of Medicine
Contact Person: Mgr. Kateřina Cetkovská, Ph.D.
Supplier department: Department of Biology - Theoretical Departments - Faculty of Medicine
Timetable
Mon 20. 2. to Fri 19. 5. Wed 13:05–13:55 B11/334; and Wed 24. 5. 13:00–13:50 B09/324
Prerequisites
( aZLBI0121c Biology I - pract. || ZLBI0121c Biology I - pract. ) && ( aZC011 Handling chemical substances || ZC011 Handling chemical substances )
Knowledge of high-school biology and all previous lectures and practical classes of the subject are prerequisities for studying the course. Expected knowledge for each lecture is specified in the course syllabus. Literature recomended to study before each lecture is detailed in the interactive syllabus of the course.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
After completion of the course student: understands elementary cellular processes and processes taking place during development of a human body; comprehends the complexity of intercellular communication and mutual regulation of individual cells in a multicellular organism; knows basic principles of bacterial and viral diseases; is able to express basic coherence between malfunction in cellular processes and development of diseases, especially hereditary diseases, cancers or developmental defects, and understands the principle of genetic determination of hereditary diseases; can explain and justify action of some therapeutics with emphasis on modern medicine. Student is also able to apply this knowledge and skills in other subject, especially physiology, pathophysiology and human genetics.
Learning outcomes
After completion of the course student: understands elementary cellular processes and processes taking place during development of a human body; comprehends the complexity of intercellular communication and mutual regulation of individual cells in a multicellular organism; knows basic principles of bacterial and viral diseases; is able to express basic coherence between malfunction in cellular processes and development of diseases, especially hereditary diseases, cancers or developmental defects, and understands the principle of genetic determination of hereditary diseases; can explain and justify action of some therapeutics with emphasis on modern medicine. Student is also able to apply this knowledge and skills in other subject, especially physiology, pathophysiology and human genetics.
Syllabus
  • 1. week:
  • DNA damage and repair – from molecular mechanisms to clinical significance (doc. Mgr. Lumír Krejčí, Ph.D.)
  • 2. week:
  • Introduction to cancer biology (Mgr. Stjepan Uldrijan, CSc.)
  • 3. week:
  • Oncogenes and oncoviruses in cancer transformation (Mgr. Stjepan Uldrijan, CSc.)
  • 4. week:
  • Tumour suppressor genes and their significance for diagnostics and therapy (Mgr. Stjepan Uldrijan, CSc.)
  • 5. week:
  • Paradigm of cancer stem cells and implications for anti-cancer therapies (doc. MUDr. Iva Slaninová, Ph.D.)
  • 6. týden:
  • Gene therapy – targets and strategies of molecular therapies (doc. MUDr. Iva Slaninová, Ph.D.)
  • 7. week:
  • Stem cells and tissue engineering – prospects of regenerative medicine (prof. Ing. Petr Dvořák, CSc.)
  • 8. week:
  • From a single cell to human I – introduction to developmental biology (Mgr. Vladimír Rotrekl, Ph.D.)
  • 9. week:
  • From a single cell to human II – molecular basis of mammalian development in health and disease (Mgr. Pavel Krejčí, Ph.D.)
  • 10. week:
  • Human genome and genomics in current biomedicine (prof. MUDr. David Šmajs, Ph.D.)
  • 11. week:
  • Human microbiome (prof. MUDr. David Šmajs, Ph.D.)
  • 12. week:
  • Bioinformatics in medicine – from molecules to populations (Mgr. Vladimír Rotrekl, Ph.D.)
  • 13. week:
  • Modern approaches in studying macromolecules and their use in current biomedicine (Mgr. Vladimír Rotrekl, Ph.D.)
  • 14. week:
  • Substitution lecture
Literature
    required literature
  • ALBERTS, Bruce. Essential cell biology. 4th edition. New York, N.Y.: Garland Science, 2014. xxiii, 726. ISBN 9780815344551. info
  • Medical genetics at a glance. Edited by D. J. Pritchard - Bruce R. Korf. 3rd ed. Chichester, England: Wiley-Blackwell, 2013. 1 online r. ISBN 9781118689028. info
    recommended literature
  • HARDIN, Jeff, Gregory BERTONI and Lewis J. KLEINSMITH. Becker's world of the cell. 8th ed. Boston: Benjamin Cummings, 2012. xxviii, 79. ISBN 9780321709783. info
  • LODISH, Harvey F. Molecular cell biology. 6th ed. New York, N.Y.: W.H. Freeman and Company, 2008. xxxvii, 11. ISBN 9780716776017. info
  • SNUSTAD, D. Peter and Michael J. SIMMONS. Principles of genetics. 5th ed. Hoboken: John Wiley & Sons, Inc, 2009. xix, 823. ISBN 9780470388259. info
  • WEINBERG, Robert A. The biology of cancer. Second edition. London: Garland Science, 2013. xx, 876. ISBN 9780815345282. info
  • WOLPERT, Lewis. Principles of development. 2nd ed. Oxford: Oxford University Press, 2002. xxv, 542. ISBN 0198792913. info
    not specified
  • CAMPBELL, Neil A. Biology. Edited by Jane B. Reece. 7th ed. San Francisco: Pearson/Benjamin Cummings, 2005. xl, 1231. ISBN 080537146X. info
Teaching methods
lecture
Assessment methods
The course Biology II builds on knowledge gained from subject Biology I - lecture (aZLBI0121p) and is completed with a written examination test taken on computers. It contains questions based on the topics discussed in the lectures and practices. The students are expected to be able to solve given problems on their own, and to derive the solutions by their own consideration based on the theory discussed in the course of both semesters and supplemented by the recommended reading.
Language of instruction
English
Further comments (probably available only in Czech)
Study Materials
The course is taught annually.
Listed among pre-requisites of other courses

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Teacher's information
https://is.muni.cz/auth/el/1411/jaro2017/aZLBI0222p/index_spring.qwarp
The course is also listed under the following terms Spring 2016, Spring 2018, spring 2019, spring 2020, spring 2021.
  • Enrolment Statistics (Spring 2017, recent)
  • Permalink: https://is.muni.cz/course/med/spring2017/aZLBI0222p