C8953 NMR Structural Analysis - seminar

Faculty of Science
Spring 2023
Extent and Intensity
0/2/0. 2 credit(s) (plus extra credits for completion). Type of Completion: z (credit).
Teacher(s)
Mgr. Jan Novotný, Ph.D. (seminar tutor)
prof. RNDr. Radek Marek, Ph.D. (seminar tutor)
Guaranteed by
prof. RNDr. Radek Marek, Ph.D.
National Centre for Biomolecular Research - Faculty of Science
Contact Person: Mgr. Jan Novotný, Ph.D.
Supplier department: National Centre for Biomolecular Research - Faculty of Science
Timetable
Wed 15:00–16:50 C04/211
Prerequisites
C8950 NMR Structural Analysis || NOW ( C8950 NMR Structural Analysis )
successful completion/simultaneous registration of C8950
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
there are 15 fields of study the course is directly associated with, display
Course objectives
At the end of the course students should be able to: analyse and interpret 1D and 2D NMR spectra; solve the structure of an unknown compound based on the spectral analysis.
Learning outcomes
Student will be able to:
- interpret 1D and 2D NMR spectra;
- understand and apply logical steps of structural analysis.
Syllabus
  • Interpretation: 1. H-1 NMR spectra. 2. C-13 NMR spectra. 3. APT. 4.+5. 1D NOE and NOESY. 6. COSY. 7. TOCSY. 8. HSQC. 9. HMBC. 10.+11. Set of spectra for one sample. 12. Presentation of group project.
Literature
    recommended literature
  • CLARIDGE, Timothy D. W. High-resolution NMR techniques in organic chemistry. 1st ed. Amsterdam: Pergamon, 1999. xiv, 382 s. ISBN 0-08-042798-7. info
  • BREITMAIER, Eberhard. Structure elucidation by NMR in organic chemistry : a practical guide. Translated by Julia Wade. Chichester: John Wiley & Sons, 1993. 265 s. ISBN 0471933813. info
  • FRIEBOLIN, Horst. Basic one- and two-dimensional NMR spectroscopy. Translated by Jack K. Becconsall. 5th completely rev. and upda. Weinheim: Wiley-VCH, 2011. xxiv, 418. ISBN 9783527327829. info
  • BRAUN, Siegmar, Hans-Otto KALINOWSKI and Stefan BERGER. 150 and more basic NMR experiments : a practical course. 2nd exp. ed. Weinheim: Wiley-VCH, 1998. 595 s. ISBN 3527295127. info
Teaching methods
Practical exercises in interpreting the NMR spectra; disscussions; group project.
Assessment methods
Participation on practical sessions, final project.
Language of instruction
Czech
Follow-Up Courses
Further Comments
The course is taught annually.
The course is also listed under the following terms Spring 2011 - only for the accreditation, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022.
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