Bi9500 General Microbiology

Faculty of Science
Autumn 2018

The course is not taught in Autumn 2018

Extent and Intensity
2/0/0. 2 credit(s) (plus 2 credits for an exam). Type of Completion: zk (examination).
prof. Ing. Luděk Žůrek, Ph.D. (lecturer), doc. Mgr. Monika Vítězová, Ph.D. (deputy)
Guaranteed by
doc. Mgr. Monika Vítězová, Ph.D.
Department of Experimental Biology - Biology Section - Faculty of Science
Contact Person: doc. Mgr. Monika Vítězová, Ph.D.
Supplier department: Department of Experimental Biology - Biology Section - Faculty of Science
Examination from organic chemistry and biochemistry.
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
Basic understanding of the main groups of microorganims with focus on bacteria and archaea from perspectives of: 1) Basic structure and function;
2) Molecular biology and genetics;
3) Metabolic diversity and growth;
4) Major taxonomic groups of bacteria and archaea;
5) Evolution (hologenome and holobiont theory), symbiosis and symbiogenesis;
6) Microbial ecology, role of microorganisms in the environment;
7) Introduction to clinical microbiology and immunity;
8) Introduction to applied and industrial microbiology and biotechnology.
Learning outcomes
Students should be able to understand the fundamental aspects of:
1) structure and function of prokaryotes and microbial eukaryotes;
2) interactions among microorganisms and between microbes and other organisms and the environment;
3) significance of microbes in evolution, environment, health and disease;
4) application of microorganisms in biotechnology.
  • Origin and Discovery of Microbial Life;
  • Microbial Diversity and Importance, Serial Endosymbiosis Theory, Holobiont and Hologenome;
  • Characteristics of Prokaryotic Cells (Cell Structure and Function);
  • Genetics (Replication, Transcription, Translation, Gene Transfer, Mutations, Genome Evolution);
  • Microbial Metabolism and Growth (Energy, Matter, and Enzymes, Catabolism of Carbohydrates and Fermentation, Aerobic and Anaerobic Respiration, Lithotrophy and Methanogenesis, Phototrophy, CO2 fixation, Nitrogen fixation);
  • Bacterial and Archaeal Diversity (Cyanobacteria, Firmicutes and Actinobacteria, Proteobacteria, Deeply Branching Gram-Negative Bacteria, Spirochetes, Chlamydiae, Planctomycetess, Archaea);
  • Microbial Ecology (Habitats and Relationships, Human Microbiome, Arthropod Microbiomes, Paratransgenesis). Clinical Microbiology (Pathogenesis and Virulence, Innate and Adaptive Immunity, Antimicrobial Drugs and Antimicrobial Resistance);
  • Introduction to Applied and Industrial Microbiology and Biotechnology.
    recommended literature
  • MADIGAN, Michael T. and John M. MARTINKO. Brock biology of microorganisms. 11th ed. Upper Saddle River, N.J.: Pearson Prentice Hall, 2006. xxv, 992. ISBN 0131968939. info
Teaching methods
Lecture - Power Point presentations
Assessment methods
Written exam consisting of 30 questions, each question is worth one point; the minimal number of points to pass the exam is 18.
Language of instruction
Further comments (probably available only in Czech)
Study Materials
The course is taught only once.
The course is taught: every week.

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