Scientific Board Meeting 14th March 2024 Budget 2023/2024 & Per-rollam results Financial results 2023 • Total expenditure in 2023: CZK 824 M (plan: CZK 835 M) • Lower spending ~ favorable energy prices (than anticipated) • Net profit before taxation: CZK 8,3 M • Extraordinary expenditures: cofunding strategic investments in NPO project (CZK 26 M of ineligible VAT) • Spending of reserve (Fund of operational resources decreases by CZK 29 M) 1,0 26,7 46,6 71,3 104,2 127,0 116,6 87,7 0 20 40 60 80 100 120 140 2016 2017 2018 2019 2020 2021 2022 2023 Balance of Fund of operational resources (mil.CZK) Budget 2024 • CZK 885 M budget plan (6 % increase) • 5 % institutional net revenue increase (CZK127,5 M) • ▲ MU allocation • ▼ CEITEC contribution to MU budget • International grants expected increase (30 %) • Operational programs increase (CZK 12,6 M => 56,4 M) • Research groups institutional budget allocation ▲ 9,5 % • Novel rules of institutional budgeting of research groups from 2024 • Flat rate CZK 2,9 M / per research group/year • Spending of reserve Budget 2024 (non-investment): Structure of Revenues Gross institutional funding 30% International grants 13%National grants 28% Commercial income 3% National Recovery Plan (NPO) 8% "Research Infrastructure" Projects 10% Operational Program VVV 8% Internally invoiced goods and services 0,3% Budget 2024 (non-investment): Structure of Expenditures Per rollam results (2023) Organisational change related to new/dissoluted research groups (6. 6. 2023 - 12. 6. 2023) • Establishment of Petr Těšina RG • 19 YES, 2 abstained from voting • Termination of P. Skladal RG • 18 YES, 3 abstained from voting • Termination of P. Lukavsky RG • 18 YES, 3 abstained from voting • Termination of Tomasz Nodzynski RG • 18 YES, 3 abstained from voting Budget plan 2023 (30. 3. 2023 – 5. 4. 2023) • 15 YES • 3 YES with reservation Quorum reached • 23 members total • Quorum needed (2/3): 15 votes Selected publications Závodník M, Fajkus P, Franek M, Kopecký D, Garcia S, Dodsworth S, Orejuela A, Kilar A, Ptáček J, Mátl M, Hýsková A, Fajkus J, Peška V. (2023) Telomerase RNA gene paralogs in plants - the usual pathway to unusual telomeres. New Phytol. Doi: 10.1111/nph.19110 Lyčka M, Bubeník M, Závodník M, Peska V, Fajkus P, Demko M, Fajkus J, Fojtová M. (2023) TeloBase: a community-curated database of telomere sequences across the tree of life. Nucleic Acids Res. 10.1093/nar/gkad672 Shen F, Xu S, Shen Q, Bi C, Lysak MA. (2023) The allotetraploid horseradish genome provides insights into subgenome diversification and formation of critical traits. Nat Commun. doi:10.1038/s41467-023-39800-y Fulneček J, Klimentová E, Cairo A, Bukovcakova SV, Alexiou P, Prokop Z, Riha K. (2023) The SAP domain of Ku facilitates its efficient loading onto DNA ends. Nucleic Acids Res. doi: 10.1093/nar/gkad850 Papageorgiou AC, Pospisilova M, Cibulka J, Ashraf R, Waudby CA, Kadeřávek P, Maroz V, Kubicek K, Prokop Z, Krejci L, Tripsianes K. (2023) Recognition and coacervation of G-quadruplexes by a multifunctional disordered region in RECQ4 helicase. Nat Commun. doi: 10.1038/s41467-023- 42503-z News from the institute Dalibor Blažek Became EMBO Member International Grants • P. Těšina: ERC Starting grant Co-translational quality control in neuronal tissue and its role in neurodegeneration and ageing (1 400 th EUR) • Z. Novotná: HORIZON WIDERA Alliance4Life Bridging the Research and Innovation Gap in Life Sciences (4 960 th EUR) • M. Zlatohurska (RG P. Plevka): MSCA PF Horizon Europe Structural characterization of phage assembly and genome packaging in bacterial cells (166 th EUR) • N. Pushkarova (RG J. Hejátko): MSCA PF Horizon Europe Novel Cytokinin-Like Compounds: Signaling and Mechanism of Action in Arabidopsis and Brassicaceae Oilseeds (166 th EUR) • M. S. Blanco (RG P. Plevka): MSCA WF Horizon Europe Structure and dynamics of phage genome ejection (150 th EUR) • J. Fousek (RG I. Rektorová): MSCA PF Horizon Europe Personalizing virtual brains with neurodegenerative disease: noninvasive stimulation approach (166 th EUR) • K. Tripsianes: HORIZON ERA: Pathway to Synergies UpstreaM synergies to overcome Locked-in effects in widEning regions and broaden internationalization pathwayS for susTainable innOvatioN and compEtitive grant applications (232 th EUR) National Grants • K. Říha: MEYS OP JAK Excellence Research TowArds Next GENeration Crops (TANGENC) (97 475 th CZK) • R. Štefl: MEYS OP JAK Excellence Research RNA for therapy (81 783 th CZK) • P. Plevka: MEYS OP JAK Excellence Research New Technologies for Translational Research in Pharmaceutical Sciences (NETPHARM) (20 000 th CZK) • K. Plevová (RG Š Pospíšilová): MEYS OP JAK Excellence Research Ready for the future: understanding long-term resilience of the human culture (RES-HUM) (11 385 th CZK) • K. Marečková: GAČR JUNIOR STAR Prenatal programming of child’s brain and behavior: Novel insights into the mechanisms (24 997 th CZK) Teaming project CIBIS (Correlative Imaging for Excellence in Biological Sciences) • The project aims to strengthen research capacities through the implementation of correlative imaging and omics methods. • Partners: • European Molecular Biology Laboratory (EMBL) • Thermo Fisher Scientific • Application procedure: • 1st phase sucessfull • 2nd phase application submitted 7. 3. 2024 Research Groups • Petr Těšina Research Group established (2023), supported by the ERC Starting grant (2024) • Selection of new group leader (2024) • Termination of three research groups (2023-2024) Organisational & Leadership News • Jiří Nováček appointed as deputy director for research infrastructure • Kateřina Hošková appointed as secretary for research infrastructure • Merge of Grant Office (preaward) and Grants Administration Department (post-award) led by Alice Valterová CEITEC PhD School Where we are: • Celebrating 10 years • Thesis Advisory Committee (TAC) • School of Microscopy (master degree, opening in September 2024) Future challenges and plans: • Quality of leadership and mentoring • Quality standards for supervisors • PhD School coordinator as a point of contact (and trust) Focus on Leadership • Leadership assessment interviews (8 group leaders in 2023) • Feedback on leadership skills by group members (anonymous) • Self-assessment of leadership skills by group leader • Feedback by colleagues from support staff • Interview • Action plan • Training opportunities • Evaluation of researchers: new system in place to support mutual evaluation interviews • E-tool streamlining the process, support by HR, monitoring • Training support Building the community and mutual understanding • Leaders Lunches established (2023) • Sip of Science launched (2024) • Employee survey: Quality and extent of administrative services (2023) RENEWAL in June 2024 INVITATION: Core Facility Day 2024 Save the date: October 16, 2024 New format presenting more campus facilities Attracting new users Hybrid event offering on-site and on-line participation Pavel Plevka pavel.plevka@ceitec.muni.cz