Osteoarthritis

                                            Z. Rozkydal

















                                          Hyaluronic acid

It forms with proteoglycans intercelullar mass

It is hydrophylic, it maintains homeostasis

It is responsible for lubrication of the joint

It promotes transport of nutritiens into the cartilage

It gives the cartilage elastic resistance

It gives rheologic properties to synovial fluid









                                         Diseases of joints

•           Osteoarthrosis deformans

•           Rheumatoid arthritis

•           Psoriatic arthritis

•           Gout

•           Ancylosing spondylitis

•           Septic arthritis



                                         Onemocnění kloubů

•           Systemic arthritis (Lupus erythematodes)

•           Haemofilia

•           Aseptic necrosis

•           Osteochondritis dissecans

•           Chondromatosis

•           Neurogenic arthropathy

•           Pigmented villonodular synovitis

                                           Osteoarthritis

•           Degenerative, slow and progressive disease of hyaline cartilage of synovial joint



•           All conditions changing the structure and function of hyaline membrane and surrounding
tissues lead to osteoarthritis

                                      Osteoarthrosis deformans

•           Primary  (after 40 years of age )



•           Secondary – the cause is known

















































































                                                R.A.

•           R.A.

•           Juvenilní R.A.

    - Still´s disease

                                                Gout

                                         Chondrocalcinosis