Forensic genetics



Genetic test
heritable disease
inheritable disease
diagnosis of heritable
disease
personal identification

DNA
= deoxyribonucleic acid
= carrier of heredity
genomic (nucleic) DNA - ncDNA
mitochondrial DNA - mtDNA

Biological material suitable
for DNA analysis
blood, blood stains
sperm, sperm stains
post-coital samples
hair, skin, nails

saliva, oral swabs
bones
teeth
tissue of muscles and
other organs

Types of DNA polymorphisms
Sequencing
polymorphism
mtDNA
SNPs
Length
polymorphism
VNTRs
STRs

Polymorphisms of sex chromosoms
Amelogenin
Y-chromosome

Types of DNA analysis
Paternity (parentage) testing
Maternity testing
Identification

Methods
Isolation of DNA
RFLP
PCR
denaturation
annealing
hybridization

Separation of DNA fragments
Hybridization
Sequencing