AUTONOMIC NERVOUS SYSTEM Functions: Contraction and relaxation of smooth muscles Function of all exocrine glands Heart rate Some metabolic processes AUTONOMIC NERVOUS SYSTEM  sympathetic NS  ncl. intermediolateralis in T1 – L2 segments of spinal cord = thoracolumbar system  paravertebral ganglia (tr. sympathicus) and prevertebral ganglia  neurotransmitters  pregangl. – acetylcholine  postgangl. – norepinephrin (ex. sweat glands and piloerector muscle)  parasympathetic NS  parasympathetic nuclei of CN III, VII, IX, X  segments S2 – S4 = craniosacral system  ganglia near the target organ  neurotransmitter acetylcholine Sympathetic system Catabolic reaction (activities that are mobilized during emergency and stress situations, “fight, fright and flight” responses) Parasympathetic system Anabolic reactions (activities associated with conservation and restoration of body resources, “rest and digest” responses) Central autonomic network Modulation of ANS  from brain cortex  tr. corticoreticularis → tr. reticulospinalis → preganglionic neurons  from hypothalamus  tr. hypothalamotegmentalis  tr. mammillotegmentalis  from hypothalamus and limbic forebrain  FLD → dorsolateral tegmentum  CC – from amygdalar complex  → hypothalamus  → PAG – coordination of somatic and autonomic response to behavior and defensive reaction → preganglionic neurons of S and PS divisions Descendent modulatory pathways  fasciculus longitudinalis dorsalis (FLD)  fasciculus telencephalicus medialis (medial forebrain bundle MFB)  tr. mammillotegmentalis Hypothalamus Nuclei of the anterior part  ncl. paraventricularis  stimulation of parasympathetic system Stimulation of the anterior part of hypothalamus  miosis  decrease in heart rate and blood pressure  dilation of cutaneous arteries  increase in peristalsis and secretion in the GIT Hypothalamus Nuclei of the posterior part  ncl. mammillaris and hypothalamicus post.  stimulation of sympathetic system Stimulation of the posterior part of hypothalamus  mydriasis  increase in heart rate and blood pressure  constriction of cutaneous arteries  decrease in peristalsis and secretion in the GIT  erection of hairs PUPILARY LIGHT REFLEX  a reflex that controls the diameter of the pupil, in response to the intensity of light (luminance) that falls on the retina of the eye  mydriasis: dilation of the pupil  miosis: constriction of the pupil ACCOMMODATION Illustrations were copied from: Neuroscience Online, the Open-Access Neuroscience Electronic Textbook Department of Neurobiology and Anatomy University of Texas Medical School at Houston