Pharmacology - practical courses

Dentistry

Spring semester 2020

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INTRODUCTION TO THE STUDY OF PHARMACOLOGY
Contents of the study of Pharmacology, contents and organization of theoretical and practical
courses and lectures, required and recommended textbooks. The conditions for granting the credit.
Pharmacology - definition, basic terminology, subspecializations, drug nomenclature. Introduction
to the prescription terminology. Classification of drug preparations. Pharmacopoeia, Pharmacopoeia
Bohemica.
INTRODUCTION TO THE PHARMACOKINETICS
Transport of drugs across biological barriers. Basic pharmacokinetic processes. Pharmacokinetic
parameters. Pharmacokinetics of single and repeated intravascular and extravascular drug
administration. Therapeutic drug monitoring (therapeutic monitoring of drug plasmatic
concentrations).
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GENERAL RULES OF THE DRUG PRESCRIPTION
Medical prescription and its essentials. Prescription of drugs. Legislation of drug prescription.
Work with various handbooks and databases (SÚKL database, Pharmindex, AISLP etc.). Prescription and
provisions of narcotic and psychotropic substances.


DRUG DELIVERY APPROACHES

Classification of administration routes. Factors related to administration route selection.
Characteristic of administration routes. Innovative administration routes.

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PRESCRIPTION OF READY MADE PREPARATIONS - practice.

SOLID DRUG DOSAGE FORMS
Prescription of selected drug forms (solid drug dosage forms – powders, capsules, tablets,
suppositories).
SOFT AND MELTING DRUG DOSAGE FORMS
Prescription of selected drug forms (soft and melting drug dosage forms – ointments, creams,
pastes, gels and other preparations for application to the skin and mucous membranes).
FLUID DRUG DOSAGE FORMS
Prescription of selected drug forms (fluid drug dosage forms - solutions for rubbing, compresses
and lavages, solutions and drops for oral administration). SPECIAL PRESCRIPTION OF INDIVIDUALLY
PREPARED DRUGS USED IN STOMATOLOGY (mucoadhesive pastes, solutions, suspensions, gels, ointments,
pastes).



PHARMACOLOGY OF PERIPHERAL NERVOUS SYSTEM - introduction
Terminology, neurotransmissions in peripheral nervous system, adrenergic and cholinergic receptors,
agonists and antagonists. Functional importance and possibilities of pharmacological affection of
sympathetic and parasympathetic system.

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PRESCRIPTION TEST (PRESCRIPTION OF READY-MADE PREPARATIONS AND LATIN TRANSLATION)


NORADRENERGIC (SYMPATHETIC) DRUGS
Receptors of noradrenergic (sympathetic) system, pharmacology of drugs activating and blocking
noradrenergic (sympathetic) system.

CHOLINERGIC (PARASYMPATHETIC) DRUGS
Receptors of cholinergic (parasympathetic) system, pharmacology of drugs activating and blocking
cholinergic (parasympathetic) system.

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MULTIPLE CHOICE FINAL (CREDIT) TEST OF PHARMACOLOGY (MCHQ - topics lessons from days 1 to 4)


GLUCOCORTICOIDS
Physiology and pathophysiology of adrenal cortex hormones. Natural and synthetic
adrenocorticosteroids, steroid receptors, mechanism of action, pharmacological use and side
effects. Examples of ready-made drug preparations.
H[1] ANTIHISTAMINES, ANTIASTHMATICS
Classification and clinical use of H[1] antihistamines. Pathophysiology of bronchial asthma, sites
and mechanisms of action of antiasthma drugs. Prescription of antitussives, expectorants,
antiasthmatics.

ANTIDIABETIC DRUGS
Course content: Therapy of type 1 and 2. DM. Insulines. Peroral antidiabetics. Examples of
ready-made drug preparations.
CREDITS