Schedule of the lectures – winter 2017


Date

Contents of the lecture

1.

18. 9.

Introductory information

Basic nomenclature: autopsy, histological necroptic and bioptical examination, the importance of
autopsies

Death and postmortal changes

Necrosis: types and appearance, causes and further evolution. Apoptosis, maceration (doc. Křen)

2.

25.9.

Atrophy, hypertrophy, hyperplasia, metaplasia (doc. Křen)

3.

2.10.

Inflammation (acute, chronic); gross and macroscopic appearance

Phagocytosis, cells engaged in inflammation

Chemical mediators of inflammation (prof. Hermanová)

4.

9. 10.

 Inflammation: types and their characteristics (superficial, deep, serous, fibrinous...)

Macroscopic & microscopic changes Fever, sepsis, pyemia Healing and reparation

Specific inflammation (tuberculosis, lues, lepra, sarkoidosis); granulomatous inflam-mation (doc.
Křen)

5.

16.10.

Immune system and its function

Immune reactions, their classification and pathology Autoimmune diseases Rejection (dr. Žampachová)

6.

23.10.

Immunodeficiency diseases (inborn and acquired)

HIV

Infections in immunocompromised patients

Infectious diseases (dr. Žampachová)

7.

30.10.

Hemodynamic disorders od perfusion (central and peripheral)

Shock, fluid loss and overload

Local disorders of circulation (infarction, embolism, edema), DIC, eclampsy (doc. Křen)

8.

6.11.

General oncology; Benign and malignant tumors and their classification

Cancerogenesis

Epithelial tumors, choriocarcinoma, mesothelioma

(prof. Hermanová)

9.

13.11.

Mesenchymal tumors

Tumors of peripheral nervous system Pigmented skin lesions

Neuroectodermal tumors of CNS (doc. Křen)

10.

20.11.

Leukemia

Lymphomas (WHO classification) (prof. Hermanová)

11.

27.11.


Cardiovascular pathology: congenital heart disease, inflammatory heart disease, ischemic

heart disease, cardiomyopathy (doc. Křen)

12.

4.12.

Cardiovascular pathology: blood vessels (degenerative changes, vasculitis), myocardial biopsy

(prof. Hermanová)

13.

11.12.

The respiratory system (prof. Hermanová)

14.

18.12.

Autopsy, biopsy

Tissue fixation, sampling and processing Frozen sections

Light, fluorescent, electron microscopy Cytology (smears, fine needle aspirations)

Routine and special staining, histochemistry, immunohistochemistry Molecular biology techniques
(flow cytometry, in situ hybridization) (dr. Sokol)