19. Acute back pain A diagnostic algorithm is derived based on whether acute back pain is traumatic or non-traumatic. Diseases of organs other than the spine, which may present with back pain, should also be considered in the context of differential diagnosis. Trauma of the spine The basic diagnostic modality for the detection of traumatic changes in the spine remains X-ray of the spine performed in two standard projections (anteroposterior and lateral), mainly due to the possibility of examination of long sections of the spina (eventually the whole spine) and a relatively low radiation dose. The sensitivity of X-ray examination is undoubtedly lower compared to CT, which, however, when examining large sections of the spine (e.g. thoracic and lubar) burdens the patient with a much higher radiation dose compared to X-ray, so this indication is not justified as a method of first choice. An exception is whole-body CT performed in polytraumatized patients, which provides a detailed assessment of the skeleton of the entire spine. The indication of this examination is given by the assumption of the presence of other life-threatening injuries (chest, parenchymal organs), which justifies the application of a higher radiation dose. If trauma on X-ray is suspected or in case of unclear findings (eventually in case of insufficient clarity of some sections of the spine), the CT examination is indicated specifically for selected levels of the spine. CT makes it possible to detect skeletal fracture lines with very high sensitivity, to classify the type of fracture (Fig. 1) and to assess the possible prominence of bone fragments into the spinal canal. A general limitation of CT is the relatively low contrast of soft tissues, so this method is not suitable for the detection of discoligamentous injury. The last of the available methods is MR examination, which does not burden the patient with radiation and allows examination of long segments of the spine in an acceptable time. Indications of MR is reserved for traumatic conditions in which the patient have a significant neurological deficit that is not explained by the finding on CT. In such a case, we look for signs of discoligamentous trauma, such as traumatic disc herniation with compression of the spinal cord or nerve roots (Fig. 2). Fresh traumatic changes in the skeletal spine, especially the compression of vertebral bodies, are characterized in the MR image by an increased T2 signal of the bone marrow corresponding to edema, which can also be used to estimate the age of the fracture. A certain limitation of MR can sometimes be difficulties in detection of skeletal fractures, which are generally better visible on CT. Non-traumatic conditions Back pain, especially in the lumbar region, is a very common clinical problem, which is one of the most common reasons for visiting a doctor. In most cases, non-traumatic back pain has no obvious cause and usually resolves spontaneously within a few weeks, sometimes referred to as non-specific back pain. In this case, the international guidelines generally oppose the routine use of imaging methods, which do not provide any essential information necessary for the treatment, which usually consists of symptomatic analgesic therapy. However, it is not a mistake to take an X-ray of the spine. In patients with back pain, however, it is necessary to take into account so-called " red flags ", i.e. significant clinical circumstances that may indicate a more serious structural pathology of the spine as a cause of back pain. These include, in particular, known or suspected oncological diseases (weight loss, etc.), long-term use of corticosteroids or other conditions leading to osteoporosis, signs of infectious disease or immunodeficiency, etc. In such cases, X-ray examination of the spine especially compression of vertebral bodies. If the problem persists or if there is a serious clinical suspicion of structural pathology of the spine, MR is the method of choice, which, in addition to assessing the severity of degenerative changes, allows to detect pathological changes of the bone marrow of the spine with sensitivity exceeding not only X-ray but also CT examination. CT, unlike MR, rather than bone marrow involvement, detects the destruction of the mineralized component of bone, which in many cases occurs in the later stages of the disease; therefore, the indication for CT examination of the spine is currently reserved almost exclusively for traumatic conditions. On MR, we can detect, for example, metastatic or inflammatory involvement of the spine in patients with back pain. In the case of metastases or other tumorous process of the skeletal spine, MR enables sensitive detection of skeletal infiltration (Fig. 3), eventually the spread of the soft tissue component of the tumor paravertebrally or into the spinal canal. The most common inflammatory diseases of the spine include spondylodiscitis, which is an infectious process affecting the intervertebral disc and adjacent parts of the vertebral bodies. The optimal imaging method for the detection of spondylodiscitis is MR, which allows to detect inflammatory changes from the early stage of inflammation in the form of edema or pathological enhancement of the intervertebral disc and adjacent parts of vertebral bodies (Fig. 4) . In these cases, where skeletal destruction is not yet present, X-ray and CT examination are not very sensitive. Methods of nuclear medicine (bone scintigraphy, PET) also have a high sensitivity for the detection of spinal inflammation, although the findings, especially in the case of bone scintigraphy, are less specific compared to MR. In patients with back pain, in addition to the anamnesis and basic physical examination, it is also appropriate to perform a neurological examination to detect radiculopathy or other neurological symptoms. In such cases, MR examination is indicated. MR enables precise visualisation of possible disc herniations and their relationship to nerve structures (Fig. 5). Other causes of back pain There are a number of diseases whose clinical picture is characterized by back pain and which can therefore mimic vertebrogenic problems. These conditions include, for example, renal colic, acute pancreatitis, and aortic dissection. Therefore, in the context of differential diagnosis, it is necessary to look for clinical and laboratory signs that may raise suspicion of these diseases. In such a case, there are indicated appropriate imaging methods targeted at specific anatomical areas, most often ultrasound or CT.