1 2 34 5 N H NH2 R R N H R2 R1 indol R2 R1 O CH3 O O H R2 R1 OH N H N R R1 OH R2 H H CH3 O O CH3 O O CH3 O O H N H N R R1 O R2 H H H N H N R H R1 R2 H H O H H CH3 O O N H NH R R1 R2 N NH R R1 R2 H3C O O H H H proton transfer N NH R R1 R2 H H HH3C O O N NH R R1 R2 H H CH3 O O H3C O O H N NH2 R R1 R2 H H R N R1 R1 NH2 H H proton transfer CH3 O O CH3 O O H R N H R1 R1 NH3 R N H R1 R1 NH3 H 6 7 [3,3] 3,3-sigmatropní přesmyk Fischerova syntéza indolů ‐ mechanismus