LECTURE 3 – Preparations used to treat
some disorders of respiratory system
Dr. Ivana Daňková
Dept. of Natural Drugs, Faculty of Pharmacy, VFU Brno
PHYTOPHARMACEUTICALS
academic year 2018/19
PHYTOPHARMACEUTICALS
vs. Respiratory system
2
 Treatment of cold,
sore throat
 Antitussive agents
 Expectorants
 Antiasthmatic drugs
 Phytomedicines are suitable supplement in the treatment of
respiratory disorders, especially of the upper respiratory tract.
 In case of bacterial complications they can support the
treatment with antibiotics.
PHYTOPHARMACEUTICALS
vs. Respiratory system
3
COMMON COLD
 an acute infectious inflammation
of the upper respiratory tract
 symptoms:
 sneezing
 running nose (due to rhinitis)
 hoarseness (laryngitis)
 difficulty in swallowing and sore throat (pharyngitis and tonsillitis),
cough associated with first serous then mucous sputum
(tracheitis, bronchitis)
 sore muscles, fever (not high), headache, and general malaise
– the symptoms can be present in various combination or
sequence
PHYTOPHARMACEUTICALS
vs. Respiratory system
4
 COMMON COLD
 the causative pathogens are different
viruses (rhino-, adeno-, parainfuenza
virus) that are transmitted by aerosol
droplets produced by coughing and
sneezing
 causative treatment with a virustatic
is impossible at present →
conventional remedies are intended
for symptomatic relief
PHYTOPHARMACEUTICALS
vs. Respiratory system
5
 Main active compounds of plants drugs:
 essential oils
 saponins
 mucilage
 other constituents of plants that can be used in
respiratory disorders:
 bitter principles
 flavonoids,…
PHYTOPHARMACEUTICALS
vs. Respiratory system
6
 ESSENTIAL OILS
 expectorant and bronchospasmolytic effect
– this is caused by a reflex action from the stomach
and by a direct action on the bronchial mucosa, since
the essential oils are partly excreted via the lungs.
Both secretion and the transport brought about the
movement of the cilia in the bronchi are enhanced.
 also the antiseptic and antibacterial effects of
essential oils are important (therapy of rhinitis, sore
throat)
PHYTOPHARMACEUTICALS
vs. Respiratory system
7
 Plant drugs containing essential oils, e.g.:
 Lamiaceae family
 Thymi herba – Thymus vulgaris, thyme
 Serpylli herba – Thymus serpyllum
 Salviae folium/herba – Salvia officinalis, sage
 Origani herba – Origanum vulgare, oregano
 Hyssopi herba – Hyssopus officinalis
 Apiaceae family
 Anisi fructus – Pimpinella anisum, aniseed
 Foeniculi fructus – Foeniculum vulgare, fennel
 plant drugs from other plant families, e.g.:
 Myrtaceae: Eucalypti folium – Eucalyptus globulus
PHYTOPHARMACEUTICALS vs. Respiratory system
ESSENTIAL OILS
8
Thymus vulgaris
herba
Pimpinella anisum
fructus
Thymus serpyllum
herba
Foeniculum vulgare
fructus
Eucalyptus globulus
folium
Hyssopus officinalis
herba
PHYTOPHARMACEUTICALS
vs. Respiratory system
9
 SAPONINS
 expectorant – secretolytic and secretomotor action
(mucolytics, mucokinetics). Saponins decrease surface
tension in aqueous solution, stimulate tracheal mucous
secretion due to the reflex action (irritating of stomach
mucose cells)
 some of the saponins have bacteriostatic, antiviral and
antiphlogistic activity
 the overdose can cause vomiting, bleeding of stomach
mucose. Do not use in case of acute gastroenteritis
 Liquiritiae radix – do not use in case of hypertension!
– due to the mineralocorticoid activity
PHYTOPHARMACEUTICALS
vs. Respiratory system
10
 Plant drugs containing saponins, e.g.:
 Liquiritiae radix – Glycyrrhiza glabra, Fabaceae, liquorice
 Saponariae radix – Saponaria officinalis, Caryophyllaceae,
 Primulae radix/flos – Primula veris, P. elatior, Primulaceae
 Verbasci flos – Verbascum densiflorum, Scrophulariaceae
 Hederae folium – Hedera helix, Araliaceae
 Polygalae senegae radix – Polygala senega, Polygalaceae
 Quillajae cortex – Quillaja saponaria, Quillajaceae
 Polygoni avicularis herba – Polygonum aviculare,
Polygonaceae
 etc.
PHYTOPHARMACEUTICALS vs. Respiratory system
SAPONINS
11
Saponaria officinalis
radix
Hedera helix
folium
Primula veris/elatior
radix/flos
Verbascum sp.
flos
Quillaja saponaria
cortex
Polygala senega
radix
PHYTOPHARMACEUTICALS
vs. Respiratory system
12
 MUCILAGE
 as an antitussive (demulcent, expectorant), especially for
irritable cough and catarrhal inflammation of the throat
 protective effect on the mucose of respiratory tract
 usually part of composite bronchial teas
 some drugs have also antibacterial effect
 mucilage drugs are suitable for inflamed mucose
of digestive tract (protective effect)
 ! mucilage decrease absorption of other drugs in small
intestine
PHYTOPHARMACEUTICALS
vs. Respiratory system
13
 Plant drugs containing mucilage, e.g.:
 Althaeae radix/folium – Althaea officinalis, Malvaceae
 Malvae folium/flos – Malva sylvestris, Malvaceae
 Farfarae folium/flos– Tussilago farfara, Asteraceae
 Plantaginis folium – Plantago lanceolata, Plantaginaceae
 Lichen islandicus – Cetraria islandica, Parmeliaceae
PHYTOPHARMACEUTICALS
vs. Respiratory system
14
Other plant drugs that can influence respiratory disorders
 Bitter principles
 due to irritating of stomach mucose membrane they can
cause the gastropulmonal reflex reaction → increase of
bronchial secret production
 ! in overdose can cause nausea, vomiting
 e.g. Gentianae radix – Gentiana lutea
 Flavonoids
 drugs containing flavonoid glycosides are usually present
in herbal tea mixtures due to their antiphlogistic,
antibacterial activity and also diaphoretic/diuretic effect
Phytotherapy of COLD
Herbal teas
15
Plant drugs with diaphoretic effect:
 diaphoretic is the state of perspiring
profusely, or something that has the
power to increase perspiration
(sweating)
 diaphoretics are used in feverish colds
and infections – to decrease elevated
body temperature
 Sambuci flos – Sambucus nigra,
Adoxaceae, black elder
 Tiliae flos – Tilia cordata, Tilia
platyphyllos, Malvaceae, lime tree
Phytotherapy of COLD
Herbal teas
16
 „Linden Flower tea“
(Megafyt)
 Tiliae flos
 loose tea, 30 g
 Black Elder Flower
(Leros)
 Sambuci nigrae flos
 20 tea bags x 1g
 sweeten to taste, ideally with
honey and lemon
 drink warm, always prepare
fresh
 Herbal tea „COLD“
(Teekanne)
 Sambuci nigrae flos
Tiliae flos
Thymi herba
Phytotherapy of COLD
Herbal teas
17
 „Cold and Flu“
(Leros)
 Cynosbati fructus
Sambuci nigrae flos
Foeniculi fructus
Tiliae flos
Menthae piperitae herba
Solidaginis herba
Lamii albae herba
black chokeberries
(= Aronia melanocarpa fruits)
 Herbal tea for COLD
(Megafyt)
 Sambuci nigrae flos
Tiliae flos
Plantaginis folium
Foeniculi dulcis fructus
Liquiritiae radix
Phytotherapy of COLD
Herbal teas
18
Other plant drugs used in
feverish colds
 Zingiberis rhizoma
– Zingiber officinale,
Zingiberaceae, ginger
 Cinnamomi cortex
– Cinnamomum verum,
Lauraceae, cinnamon
 Herbal tea „COLD with ginger“
(Teekanne)
 ginger (Zingiber officinale) 29 %
rooibos (Aspalathus linearis) 23 %
linden flower (Tilia sp.) 12 %
black elder flower (Sambucus nigra) 11 %
spearmint leaf (Mentha spicata) 7 %
lemon grass (Cymbopogon sp.) 5 %
liquorice root (Glycyrrhiza glabra) 4 %
chicory root (Cichorium intybus) 4 %
cinnamon (Cinnamomum verum) 4 %
Phytotherapy of RHINITIS
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 locally applied preparations cause vasoconstriction
(narrowing the blood vessels) in the nasal area, reduce
swelling and congestion of the nasal mucosa and dry up
secretions, clearing the nasal passages
 α-sympathomimetics
H1-antihistaminics
 plant drugs with content of essential oils, more often
isolated essential oils or isolated compounds as
disinfectants
 Menthae piperitae etheroleum, menthol
 Thymi etheroleum, thymol
 Eucalypti etheroleum
 Lavandulae etheroleum
 Pini sylvestris etheroleum
Eucalyptus globulus
Phytotherapy of RHINITIS
Nasal preparations
20
 PINOSOL NAS GTT SOL 1X10ML
(Zentiva)
 Pini etheroleum 0,3752 g
Menthae piperitae etheroleum 0,10 g
Eucalypti etheroleum 0,05 g
Thymolum 0,0032 g
Guaiazulenum 0,002 g
Tocoferoli alfa acetas 0,17 g in 10 g of oil solution
 SUKL code: 0099339,
OTC medicinal product
 ATC: R01AX30
(Other nasal preparations, combinations)
 PINIO-NASAL drops, spray
(Rosen Pharma)
production is
terminated, 2017
https://www.pinio-nasal.cz/
Phytotherapy of RHINITIS
Nasal preparations
21
 RYMASTOP SPRAY
(Dr. Weiss)
 contains extracts of 10 herbal drugs:
Euphrasia rostkoviana, Viola odorata, Malva mauritiana,
Equisetum arvense, Tilia cordata, Calendula officinalis,
Sambucus nigra, Plantago lanceolata, Achillea millefolium,
Eucalyptus globulus
+ hyaluronic acid, Boswellia serata resin extract
 immediate relief from the stuffy nose
 gently cleans, regenerates and moisturises
the nasal mucosa
 suitable for long-term use
 also for pregnant and lactating women
Phytotherapy of RHINITIS
Nasal preparations
22
 ASPECTON nasal spray
(Krewel Meuselbach)
 hypertonic solution of sea
salt
 camphor, levomenthol,
dexpanthenol
 Thymi etheroleum, Eucalypti
etheroleum, Menthae
piperitae etheroleum
 PHYSIOMER ® Eucalyptus
nasal spray
(Le Laboratoire de la Mer)
 hypertonic solution of sea salt
(22 g/l)
 Eucalypti etheroleum,
Menthae pip. etheroleum
Phytotherapy of RHINITIS
Nasal preparations
 PantheNose® nasal spray
(Dr. Müller Pharma)
 with Aloe vera
with escin
with Eucalyptus oil
 PantheNose® nasal ointment
(Dr. Müller Pharma)
 with essential oils: Eucalypti,
Menthae pip., Thymi, Myrti
Lavandulae, Pini pumilionis
etheroleum
 TONASOL nasal drops 10 ml
(Topvet)
 with TTO = Tea tree oil
(Melaleuca alternifolia)
23
Phytotherapy of RHINITIS
Nasal preparations
24
 BOROZAN Nasal ointment
(Zentiva)
 ointment with protective effect
on skin around nose
 Eucalyptus oil, Niaouli oil
(Melaleuca viridiflora), Balm
mint oil, Sandalwood oil
 Zinci oxidum, Tin oxide,
Acidum boricum, Methylis
salicylas
 KOSMÍN Nasal ointment
(Aromatica)
 emulgel containing
essential oils:
Camphor
Thymol
Menthae pip. etheroleum
Turpentine
Eucalypti etheroleum
Phytotherapy of COLD, RHINITIS
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 SINUPRET POR GTT SOL 1X100ML
(Bionorica-Schwabe)
 Extractum herbarum aquae-spirituosum:
Gentianae radix
Primulae flos
Rumicis herba
Sambuci flos
Verbenae herba
 SUKL code: 0075868
OTC product
 ATC: V11
 SINUPRET POR TBL OBD 50
 SINUPRET Forte POR TBL OBD 20
 SINUPRET AKUT POR TBL OBD 20
Phytotherapy of COLD, RHINITIS
26
 RYMANOS SIRUP 150 ML
(PharmaSwiss)
 Sambuci nigrae flos
Verbenae herba
Althaeae radix
Gentianae radix
 for adults and children up to 3 years
 RYMANOS TBL
 Sambuci nigrae flos
Verbenae herba
Origani herba
Althaeae radix
Majoranae hortensis herba
 for adults: 2 tablets a day
Phytotherapy of SORE THROAT
27
 = pain or irritation of the throat.
A common physical symptom that
is usually caused by acute
pharyngitis (= inflammation
of the throat)
 ! important information – whether
the infection of throat is viral or
bacterial → for the treatment of
bacterial infections recommend a
visit of a physician!
Phytotherapy of SORE THROAT
28
 lozenges (pastilles)
 for sucking
 contain extracts of plant drugs with
the content of
 mucilage – lubricating and soothing
effect on irritated mucose membrane
of throat
 essential oils – as disinfectants
 ! sometimes containing local (surface)
anesthetics
 other forms
 gargles, drops, tinctures, mouth
sprays
Phytotherapy of SORE THROAT
29
 Lichen islandicus, iceland moss
Cetraria islandica
 contain mucilage (water soluble polysaccharides)
– lichenin, isolichenin and bitter-tasting lichen
acids (antibiotically active !)
 as a demulcent and expectorant
for alleviating irritation of the throat;
bacteriostatic effect of lichen acids
 immunostimulating effect
 (for a lack of appetite and gastroenteritis
– lichen acids)
Lichen islandicus, iceland moss
30
 a spray-dried extract is a component of instant bronchial and
cough teas
 together with other plant drugs in various preparations for
cough (antitussives, expectorants) and cold, chills, etc.
 making the tea: Boiling water is poured over 1,5-2,5 g of finely
chopped drug, after 10 min passed through a tea strainer. To
obtain an expectorant which has plenty of mucilage, but which
is less bitter, it has been suggested that after pouring the hot
water over the drug, the water should be immediately
discarded (it contains most of the lichen acids) and then more
hot water added. However, doing this also removes the
antibiotically active constituents.
Phytotherapy of SORE THROAT
Lozenges
31
 Lichen islandicus
 ISLA Moos, ISLA Cassis
ISLA Mint (Engelhart Arzneimittel)
 HERBALMED Dr. Wiess
 ANGINAL Dr. Müller Pharma
 DOLO-ANGIN (Diva Pharma)
 + benzocaine 10 mg (local anesthetic) !
 ASPECTON (Krewel Meuselbach), etc.
Phytotherapy of SORE THROAT
32
 Salviae folium/herba
 constituents: essential oils (mainly
monoterpenes), tannins, rosmarinic
acid, diterpene bitter compounds
 as an antiphlogistic for inflammation
of mouth and throat, for gingivitis,
stomatitis – mainly in the form of
gargle
 application forms – for external use:
fluid extracts, tinctures (for gargle),
sprays, lozenges
Phytotherapy of SORE THROAT
33
 FLORSALMIN
(Zentiva)
 concentrate for gargle
 Salviae officinalis folii tinctura (1:6,6)
extracted with ethanol 60% (V/V)
 SUKL code: 0093779
 ATC: V11 (Phytopharmaceuticals and animal
products)
 Salviae tincture
 e.g. Grešík – extract 10 (m/V) of Salviae off.
folium in ethanol 35% (V/V)
Phytotherapy of SORE THROAT
34
 Salviae folium
 ANGINAL Dr. Müller Pharma –
lozenges, mouth spray
 Galmed, Dr. Theiss, HerbalMed, ...
Phytotherapy of SORE THROAT
35
 other products, e.g. with:
 Eucalypti etheroleum
 Tea tree oil – essential oil of Melaleuca
alternifolia leaves – antiseptic effects
 SEPTOLETE D lozenges
(Krka, Slovenia)
 Benzalkonii chloridum 1mg
 Mentholum 1,2mg, Menthae piperitae
etheroleum 1,0mg, Eucalypti etheroleum 0,6mg,
Thymolum 0,6mg in 1 pastille
Phytotherapy of COUGH
36
 a cough is a protective reflex with
sudden noisy expulsion of air that
tries to remove the irritant and to
clear the airways.
 coughing starts when part of your
breathing passage becomes
inflamed or irritated by matter
such as dust, smoke or mucus
(sputum)
 cough is controlled due to the
cough center
Phytotherapy of COUGH
37
 important information – the characteristic of cough –
whether there is „dry“ cough or „chesty“ cough
(non-productive/productive), or acute/chronic cough
Phytotherapy of COUGH
38
 „dry cough“, non-productive is irritating, exhausting
 antitussive agents
 centrally acting – suppress cough by a direct action on
medullary cough center (opioid alkaloids and their
derivatives – codeine, noscapine, dextrometorphan;
synthetic drugs)
 peripherally acting – they suppress cough reflex by
decreasing the input of stimuli from cough receptors
in respiratory passages
 pharyngeal demulcents – soothing action on irritating
mucosa - they provide relief to throat, promotes salivation
& inhibit impulses from inflamed mucosa
 steam inhalation
Phytotherapy of COUGH
ANTITUSSIVES
39
 antitussive phytomedicines – predominantly mucilage
plant drugs and their preparations (herbal teas, drops,
syrups,...)
 Althaeae radix/folium – Althaea officinalis, marshmallow
 Farfarae folium/flos– Tussilago farfara, coltsfoot
 Malvae folium/flos – Malva sylvestris, common mallow
 Plantaginis folium – Plantago lanceolata, plantain
 Verbasci flos – Verbascum densiflorum, mullein
 Lichen islandicus – Cetraria islandica, iceland moss
Phytotherapy of COUGH
40
 „chesty cough“, productive (the sputum is coughed up)
 expectorants
 secretolytic (mucolytic) – reduce the viscosity of mucus,
stimulate production of watery mucus
 secretomotor (mucokinetic)
 emetic – Ipecacuanhae radix (emetine)
 bronchodilatants
 mostly synthetic drugs
Phytotherapy of COUGH
EXPECTORANTS
41
 expectorant phytomedicines – predominantly plant drugs
with the content of saponins and essential oils
 various preparations (herbal teas – mostly mixtures; drops,
syrups,...)
 often combination of expectorants and antitussives (Species
pectorales, bronchial teas...)
 the most frequently used plant drugs:
 saponine drugs – Liquiritiae radix, Verbasci flos, Primulae
radix, Hederae folium...
 drugs with essential oils – Thymi herba, Serpylli herba,
Origani herba, Foeniculi fructus, Anisi fructus, Salviae folium
 also mucilage drugs are used in bronchial teas
Phytotherapy of COUGH
EXPECTORANTS
42
 MIXTURA SOLVENS (= a sputum dissolving mixture)
 according the old prescription (Prescriptiones pharmaceuticae 1972):
Ammonium chloratum 25 g
Extractum liquiritiae siccum 25 g
Aqua conservans 950 g
 brown liquid with mild odour and sweet-salty taste
1 lozenge contains:
120 mg dry extract of liquorice root (3-4 :1),
180 mg Ammonium chloride
Water
Phytotherapy of COUGH
Herbal teas
43
 SPECIES PECTORALES Planta
(Leros)
 Plantaginis folium
Althaeae radix
Farfarae flos
Menthae piperitae herba
Liquiritiae radix
Verbasci flos
Foeniculi fructus
 SUKL code: 0000965, OTC
 ATC: V11
 CI: pregnancy, nursing, hypersensitivity to any
constituent
 Do not use longer than a week without
consulting your physician.
Phytotherapy of COUGH
Herbal teas
44
 Bronchial tea
(Leros)
 Cynosbati fructus
Origani herba
Foeniculi fructus
Tiliae flos
Menthae piperitae herba
Thymi herba
Verbasci flos
Plantaginis folium
 Bronchial Tea
(Megafyt Pharma)
 Plantaginis folium
Althaeae radix
Cynosbati fructus sine semine
Liquiritiae radix
Serpylli herba
Tiliae flos
Phytotherapy of COUGH
Herbal teas
45
 Pulmoran (Leros)
 Salviae folium
Althaeae radix
Polygoni avicularis herba
Thymi herba
Urticae herba
Foeniculi fructus
Sambuci nigrae flos
Plantaginis folium
Liquiritiae radix
 9 plant drugs!
 Herbal tea „Bronchi“
(Megafyt Pharma)
 Serpylli herba
Matricariae flos
Sambuci nigrae flos
Tiliae flos
 bronchial tea with diaphoretic
effect
Phytotherapy of COUGH
Herbal teas
46
 Bronchial tea
(Herbalist Pavel Váňa)
 Malvae folium
Filipendulae herba
Althaeae radix
Origani herba
Hyssopi herba
 „Bronchi and Lungs“
(Teekanne)
 Anisi fructus (30,8 %)
Foeniculi fructus
Liquiritiae radix
Thymi herba (5,8 %)
Salviae officinalis folium (4,9 %)
Serpylli herba
Phytotherapy of COUGH
Herbal teas
47
 Children Bronchial Tea
(Megafyt Pharma)
 Foeniculi fructus (25 %)
Anisi fructus (20 %)
Sambuci nigrae flos
Tiliae flos
Althaeae radix
Liquiritiae radix
Primulae radix
Serpylli herba
 suitable over
the 6th month
 Children Tea „Cough,
bronchi“
(Leros Baby)
 Cynosbati fructus
Serpylli herba
Anisi fructus
Tiliae flos
Sambuci nigrae flos
Verbasci flos
 suitable over
the 6th month
Phytotherapy of COUGH
Drops, tinctures, syrups, medicinal solutions
48
 PLEUMOLYSIN gtt.
(IVAX/TEVA)
 Saponinum 5 mg
Codeini phosphas hemihydricus 3,06 mg
Aconiti tinctura 40 mg
Aurantii tinctura 150 mg
Thymi extractum fluidum 30 mg
in 1 ml (= 33 drops).
 SUKL code: 0000725
 ATC: R05FA01 (Opioid derivatives and
mucolytics)
 Prescription-only medicinal product !
(due to presence of codeine, Aconiti tinctura)
Phytotherapy of COUGH
Drops, tinctures, syrups, medicinal solutions
49
 THYMOMEL syrup
(IVAX/TEVA)
 in 100 ml:
Thymi extractum fluidum 4.1624 g
Serpylli extractum fluidum 4.1630 g
Plantaginis extractum fluidum 4.1666 g
 SUKL code: 0045339, OTC product
 ATC: V11
(Phytopharmaceuticals and animal products)
 suitable for children over 1 year of age
 content of 3.5 % of alcohol
Phytotherapy of COUGH
Drops, tinctures, syrups, medicinal solutions
50
 MUCOPLANT
Syrup against cough with plantain and honey (Dr. Theiss)
 active constituents (in 100 g):
Plantaginis extractum fluidum 5.00 g,
Menthae piperitae etheroleum 0.01 g
 Sirupus simplex (50 g), honey (2 g),…
 SUKL code: 0016289,
OTC product
 ATC: V11
 suitable for children over 3 years of age
 content of 1.27 % of alcohol
Phytotherapy of COUGH
Drops, tinctures, syrups, medicinal solutions
51
 BIOTUSSIL POR GTT SOL 1X100ML
(Biomedica)
 content in 100 g:
Herbarum Extractum pro Biotussil 97.80 g:
(ex. Gentianae radix 0.20 g, Primulae flos 1.50 g,
Plantaginis folium 1.50 g, Thymi herba 1.50 g,
Liquiritiae radix 1.50 g, Sambuci flos 1.50 g
extracted with ethanol 23% (m/m)
Foeniculi amari fructus etheroleum 0.05 g,
Anisi stellati etheroleum 0.05 g
 SUKL code: 0067133, OTC product
 ATC: V11
 suitable for children over 4 years of age
Phytotherapy of COUGH
Drops, tinctures, syrups, medicinal solutions
52
 HEDELIX POR SOL 1X100ML/2GM
(Krewel Meuselbach GmbH)
 Hederae folii extractum siccum 0.8 g/100 mL
Anisi stellati fructus etheroleum
 SUKL code: 0043903, OTC product
 ATC: R05CA12
 available also in drops
 PROSPAN SIR 100 ML
(Engelhard Arzneimittel GmbH)
 Hederae helicis folii extractum siccum
(5-7.5:1) 0.7 g/100 ml
 SUKL code: 0202353, OTC product
 ATC: R05CA12
Phytotherapy of COUGH
Drops, tinctures, syrups, medicinal solutions
53
 BRONCHIPRET syrup (Bionorica-Schwabe)
 Thymi herba extract
Hederae folium extract
 SUKL code: 0136001, OTC product
 ATC: V11
 suitable for children over 1 year of age
 BRONCHIPRET tablets
 Thymi herba extract
Primulae radix extract
 SUKL code: 0058921, OTC product
 ATC: V11
 suitable for children over 12 years of age
Phytotherapy of COUGH
Drops, tinctures, syrups, medicinal solutions
54
 KALOBA POR GTT SOL 1X20ML
(Bionorica-Schwabe)
 EPs® 7630 – Pelargonium sidoides root extract
Pelargonii sidoidis extractum fluidum
 each 10 g (9.75 mL) of solution contains
8 g of extract
 SUKL code: 0023998, OTC product
 ATC: V11
 dosage: children 1-5 y. 3x 10 drops
children 6-12 y. 3x 20 drops
adults and children over 12y. 3x 30 drops
 also available as syrup and tablets
Phytotherapy of COUGH
Drops, tinctures, syrups, medicinal solutions
55
 ERDOMED HERBAL syrup
(Angelini Pharma)
 contains extracts from:
Thymus vulgaris,
Pelargonium sidoides,
Echinaceae purpurea,
Panax quinquefolius
 + vitamin C, zinc
+ Sirupus simplex, honey
 dosage:
children 2-6 y. 2.5 mL 3 times
adults and children over 6y. 5 mL 3 times
Phytotherapy of COUGH
Drops, tinctures, syrups, medicinal solutions
56
 VINCENTKA Syrup with plantain
and mother of thyme
 content:
natural medicinal mineral water „Vincentka“
hydroalcoholic extract of Plantaginis
folium and Serpylli herba
 suitable for children over 3 years of age
Phytotherapy of COUGH
Drops, tinctures, syrups, medicinal solutions
57
 „Tatras bronchial mixture – syrup“
(Fytopharma, Slovakia)
 composition – extracts of:
Althaeae radix
Malvae flos
Thymi herba
Menthae piperitae herba
Lichen islandicus
 suitable for children over 3 years
Phytotherapy of COUGH
Ointments, balms
58
 Breast balm (Dr. Müller Pharma)
 for better breathing in cold
 contains essential oils (from Pinus, Mentha
piperita, Eucalyptus, Abies), menthol,
camphor
 apply on the skin of chest and back and
massage a few times daily
 suitable also for children over 3 years
 Breast balm (Aromatica)
 for better breathing in cold
 contains essential oils (from Pinus sylvestris,
Mentha piperita, Lavandula angustifolia,
Eucalyptus globulus), camphor, thymol
PHYTOPHARMACEUTICALS vs. HOMEOPATICS
59
TRADITIONAL HERBAL PRODUCT
for cough releif
(previously as homeopatic product!)
HOMEOPATHIC MEDICINE
recommended to relieve cold
symptoms, sore throat, dry or
wet cough
PHYTOPHARMACEUTICALS vs. HOMEOPATICS
60
 STODAL POR SIR 1X200ML
 content in 100 g of syrupu:
 homeopatic compenents:
Drosera tinctura a.u.h. (?)
Pulsatilla 6 CH, Rumex crispus 6 CH, Bryonia 3 CH,
Ipecacuanha 3 CH, Euspongia officinalis 3 CH,
Sticta pulmonaria 3 CH, Kalii stibii tartras 6 CH,
Myocardium 6 CH, Dactylopius coccus 3 CH
together 9,5 g (?)
 non-homeopatic components:
Balsami tolutani sirupus 19,0 g
Polygalae sirupus 19,0 g
 Sirupus simplex, benzoic acid, ethanol 96% (as a part of tinctures)
 SUKL code: 0060073
 ATC: V11 (= Phytopharmaceuticals) !!
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