Retinoids
                                   Vitamin A and its derivatives

                                             Retinoids

                                             Retinoids

                                           Mode of action

                                           Mode of action

                                           Retinoic acid

                                     Retinoid-binding proteins





                         Disruption of retinoid signalling by xenobiotics

                          Consequences of retinoid signalling disruption

                         Disruption of retinoid signalling by xenobiotics

                                      In vivo tests to assess
                                  retinoid signalling disruption

                                          In vitro tests