Title: Study of the Photoreaction Mechanisms of Photoactivatable Compounds

Bokolombe Pitchou Ngoy


Abstract.

Recent investigations of photochemists have focused on the mechanistic design, synthesis and study
of photoreleasable protecting groups. The overall goal is to create a suite of protecting groups
whose release can be triggered using inexpensive light sources. The development of new
photoactivatable moiety responds to the current search for a new methodology for biological and
other applications. The development of the photoremovable protecting group also brings a new
strategy in organic synthesis. The aim of my work was to study the mechanisms of new types of
photoreactions using fast kinetic techniques, such as laser flash spectroscopy. Femtosecond and
nanosecond time-resolved spectroscopy, which have been used together with theoretical calculations
to detect the reaction intermediates, will be introduced in my presentation.