Anion Receptor Bambus[6]uril


Jan Svec, Vladimir Sindelar


 Department of Chemistry, Masaryk University, Kamenice 5, 625 00 Brno, Czech Republic



Glycoluril is a rigid bicyclic molecule that has been used as a building block of various
supramolecular objects. Besides acyclic supramolecular hosts based on glycoluril, such as molecular
clips, glycoluril oligomers and capsules, the most attention is paid to macrocyclic compounds -
cucurbiturils. Recently, we prepared a new macrocyclic derivatives based on glycoluril -
bambus[6]uril (BU[6]). The macrocycle is prepared by acid catalyzed condensation between
2,4-dimethylglycoluril and formaldehyde. The reaction is carried out in diluted HCl which acts not
only as a catalyst but also as a template. BU[6] and chloride anion form an inclusion complex in
which anion is localized in the middle of positively charged cavity of the macrocycle. In our
poster presentation, we will present the ability of BU[6] to bind various anions in various solvent
mixtures with high affinity and selectivity. We will also discuss method for the preparation of
anion-free macrocycle.


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                                        BU[6]·HCl complex^

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Support for this work was provided by the Grant Agency of the Czech Republic (P207/10/0695) and the
project CETOCOEN (no. CZ.1.05/2.1.00/01.0001) from the European Regional Development Fund.