AMINOKYSELINY ACIDOBAZICKÉ vlastnosti Izoelektrický bod Tabulka pK Skupina pK Skupina pK Skupina pK a COOH 1.8 - 2.5 b COOH 3.9 g COOH 4.1 a NH[2 9 - 10 e NH[2 10.8 guanidin 12.5 ]imidazol 6.0 ]SH 8.3 OH 10.1 +--------------------------------------------------------------------------------------------+ |AMK | Symboly |AMK | Symboly | |----------------------+-----------------------+----------------------+----------------------| |glycin | Gly | G |methionin | Met | M | |----------------------+-----------+-----------+----------------------+-----------+----------| |alanin | Ala | A |glutamová k. | Glu | E | |----------------------+-----------+-----------+----------------------+-----------+----------| |valin | Val | V |asparagin | Asn | N | |----------------------+-----------+-----------+----------------------+-----------+----------| |leucin | Leu | L |glutamin | Gln | Q | |----------------------+-----------+-----------+----------------------+-----------+----------| |izoleucin | Ile | I |lysin | Lys | K | |----------------------+-----------+-----------+----------------------+-----------+----------| |serin | Ser | S |arginin | Arg | R | |----------------------+-----------+-----------+----------------------+-----------+----------| |threonin | Thr | T |tyrosin | Tyr | Y | |----------------------+-----------+-----------+----------------------+-----------+----------| |cystein | Cys | C |fenylalanin | Phe | F | |----------------------+-----------+-----------+----------------------+-----------+----------| |histidin | His | H |tryptofan | Trp | W | |----------------------+-----------+-----------+----------------------+-----------+----------| |prolin | Pro | P |asparagová k. | Asp | D | +--------------------------------------------------------------------------------------------+ b alanin ornitin a citrulin g aminomáselná antibiotika - azaserin, cykloserin, chloramfenikol nervové mediátory - DOPA, dopamin, adrenalin hormony - thyroxin, trijodthyronin 1. Úplná hydrolýza - kyselá - 6 M HCl,, 100 - 120 ^oC, 10 - 100 hod. - bazická - 2 - 4 M NaOH, 100 ^oC, 4 - 8 hod. - enzymová - Pronasa