Kyselina acetylsalicylová:
Paracetamol:
Cl
NO2
NaOH
OH
NO2
Fe, H+
OH
NH3
+
1. Na2CO3
2. Ac2O
OH
HN Me
O ¨
Diklofenak:
Barbituráty:
C CH
1. EtMgBr
2. CH3CH=O
3. H2O, H+
C C
OH
CH3
PBr3
C C
Br
CH3
COOEt
COOEt
1. EtONa
2. CH2=CHCH2Cl
CH2=CHCH2
COOEt
COOEt COOEt
COOEtCH2=CHCH2
C
CH3
C
CH3CH2 CH3CH2 CH3CH2
CH3CH2
EtONa
C C
Br
CH3
CH3CH2
Propofol:
Vysvětlení mechanismu (http://www.rsc.org/Education/EiC/issues/2007Jan/PhenolsMedicine.asp):
Benzodiazepiny: