Biomacromolecular structure analysis - channels Radka Svobodová CEITEC, Masaryk University MOLEonline 2 MOLEonline: Web application for detection of channels and pores and calculation of their geometrical and physico-chemical properties New features: ▪ Automatic detection of transmembrane pores ▪ Visualization of properties on the channel’s profile ▪ Interconnection with other bioinformatics tools (PDBe, CSA, ChannelsDB, OPM, UniProt) and data transfer from them ▪ Integration of LiteMol suite .Pravda L., Sehnal D., Toušek D., Navrátilová V., Bazgier V., Berka K., ... & Koča J., Otyepka M. (2018). MOLEonline: a web-based tool for analyzing channels, tunnels and pores (2018 update). Nucleic acids research. MOLEonline 3 MOLEonline 4 MOLEonline 5 MOLEonline 6 MOLEonline 7 MOLEonline 8 MOLEonline 9 MOLEonline 10