Biomolecular Chemistry

Journey inside the cell

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The programme of Biomolecular Chemistry involves gaining knowledge of the structure of biologically significant molecules and the relationship between their structure and functions.

The aim of the programme is to prepare specialists with high level of expertise in biochemistry, enzymology, structural biology, molecular genetics, protein engineering and bioinformatics with the focus on the structure, dynamics and functions of biologically important molecules and molecular complexes.

The core courses are formed by mathematical, physical, chemical and biological disciplines: general and organic chemistry, analytical chemistry, physical chemistry, structural chemistry, biochemistry, microbiology, molecular biology, information technology, data processing and informatics. Students will learn to work with literature and present their results orally and in writing, both in Czech and English. The aim of such preparation is to provide a theoretical basis for post-gradual studies, as well as equip students with practical skills in the fields mentioned above, which subsequently could be employed in basic and applied research. Based on this, other courses of the study programme, focusing on general biochemistry and enzymology, are developed. As a result, the graduates can work in a wide range of professions requiring biochemistry education. Newly developing disciplines, like structural biology, protein engineering and bioinformatics are of paramount significance in this study programme.

Teaching aims at: acquiring knowledge about the structure of proteins, nucleic acids and sugars; developing the ability to describe their basic structural characteristics; and gaining information about primary, secondary and tertiary structure of these biomolecules. Theoretical and practical knowledge of crystallography of biopolymers, NMR studies of their structure and dynamic properties, and the knowledge of: molecular modelling, molecular dynamics and computational chemistry and biochemistry are integral parts of the studies.

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After successfully completing his/her studies the graduate is able to:

  • specify and creatively solve problems in the field of general biochemistry, enzymology, structural biology, molecular genetics, protein engineering and bioinformatics
  • use selected advanced research methods like molecular modelling, molecular dynamics, computational chemistry and biochemistry, crystallography of biopolymers or NMR studies
  • based on available sources, specify tasks and coordinate professional work in the field of general biochemistry, enzymology, structural biology, molecular genetics, protein engineering and bioinformatics
  • understand and use information available in professional literature and electronic databases which are concerned with the structure and function of biologically significant molecules: proteins, RNA and DNA
  • comprehensibly and convincingly communicate their expert opinion to specialists and lay-people
  • run a discussion within their expert knowledge, skills and qualifications in at least one foreign language (i.e. English)
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Graduates can find employment in biochemical, pharmaceutical, veterinary, or medical research, both basic and applied, or in biotechnological plants of the above mentioned character. They can also easily adapt to work in a different field. The consecutive post-gradual study gives them an opportunity for a perspective employment in the labour market home and abroad.

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Students make up their study plans according to the rules governing a given study programme. While doing so, students must comply with the principles of the Study and Examinations Regulations of the faculty and Rules and Conditions for the Creation of a Study Plan. As a starting point, students can adopt the recommended study plan, which evenly distributes the whole study throughout the standard duration of two years, and ensures students the fulfilment of all the required obligations necessary for a successful completion of this degree study in its standard length. The faculty's timetable (allocation of time and space to courses taught in a given semester) is compiled with consideration of the recommended study plans.

To be admitted to the final state examination students must obtain a total of 120 ECTS credits for required, selective and elective courses.

A total of 11 credits must be obtained for successfully completing required courses. The required courses in the Biomolecular Chemistry programme are: course C7920 - The Structure and Functions of Proteins, C7925 - The Structure and Dynamics of Nucleic Acids and C2135 - Bioinformatics in Practice. A compulsory course without credit rating, C7777 - Handling Chemical Substances is a two-hour block lecture that must be completed at the beginning of each academic year. Attending the lecture is a prerequisite to enrolment in all courses where dealing with chemical substances takes place (laboratory classes, diploma theses, etc.).

Students must obtain a minimum of 15 credits for completing at least one selective course in one of the following four groups of disciplines: group I, focusing on enzymology, biosensors and characteristics of proteins; group II: computational chemistry and molecular modelling; group III: NMR spectroscopy; group IV: crystallography. The remaining selective courses comprise CB060, CC060 - Specialized Seminar (8 credits) and Diploma Thesis.

A total of 34 credits must be obtained for completing elective courses. Those are all the courses taught in a given period at the Faculty of Science and other faculties of Masaryk University in which students are eligible to enrol. The selection of optional courses is determined by an obligation to earn a minimum of 108 credits for courses in natural sciences, mathematics or informatics, out of which at least 96 credits must be earned for courses in chemical and biological disciplines.

Furthermore, students must write up their diploma theses, for which they earn 50 credits.

Before being admitted to the final advanced state examination, students must successfully pass an exam in JA002, English for Specific Purposes at the B2 level according to CEFR, unless they did so during their Bachelor's studies.

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Not required

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General graduation requirements conform to the Study and Examination Regulations of Masaryk University (http://is.muni.cz/do/rect/normy/vnitrnipredpisy/Studijni_a_zkusebni_rad.pdf).

The final state examination (advanced Master's) is oral and it is held in the Czech language. It covers the core course of Biomolecular Chemistry (general biochemistry and enzymology, and structural biology and its methods) and two optional courses out of the following: 1) Molecular Modelling and Bioinformatics, 2) Experimental Methods of the Structural Biology, 3) Molecular Biology and Genetics, 4) Biophysics.

The aim of the examination is to verify whether a student is able to participate in a discussion showing expertise in the field. The examination does not intend to repeat exams in individual courses and test the detailed knowledge of theory and evidence. Its purpose is to demonstrate students' general knowledge of basic concepts and outcomes concerning individual disciplines and their interrelations in a broader sense.

Another component of the final state examination is the defence of a Master's thesis. By writing up their theses, students show a good grasp of issues relating to the topics of the theses and the capability of a specialist work under the guidance of their supervisors. The elements assessed at the defence are: comprehension of the topic of a Master's thesis and the level of its presentation.

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Graduates of this Master's degree study programme can, after satisfying the admission requirements, follow up with PhD programmes focused on biochemistry and life sciences (Biomolecular Chemistry, Structural Biology or Biochemistry at the Faculty of Science of Masaryk University).

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Field of study specifications

Field of Study: Biomolecular Chemistry
Abbreviation: BIOM
Code: 1406T004
Type: Advanced Master's state examination
Degree: RNDr.
Accreditation: to 31/12/2024
Programme: R1406 Rig-BCH Biochemistry
Faculty of Science
Field of study guaranteed by:
Faculty of Science

Additional information is available at http://www.sci.muni.cz/cz/BcMgrStudium/