# LF:ASTAc Biostatistics - practice - Course Information

## ASTAc Biostatistics - practice

**Faculty of Medicine**

Autumn 2017

**Extent and Intensity**- 0/1/0. 2 credit(s). Type of Completion: z (credit).
**Teacher(s)**- prof. RNDr. Ladislav Dušek, Ph.D. (seminar tutor)

RNDr. Jiří Jarkovský, Ph.D. (seminar tutor)

RNDr. Danka Haruštiaková, Ph.D. (seminar tutor)

Mgr. Jan Švancara (seminar tutor)

RNDr. Tereza Nečasová (seminar tutor)

Mgr. Ivana Katinová (seminar tutor) **Guaranteed by**- prof. RNDr. Ladislav Dušek, Ph.D.

Institute of Biostatistics and Analyses – Other Departments for Educational and Scientific Research Activities – Faculty of Medicine

Supplier department: Institute of Biostatistics and Analyses – Other Departments for Educational and Scientific Research Activities – Faculty of Medicine **Timetable of Seminar Groups**- ASTAc/01: Thu 14:00–15:40 D29/347-RCX2

ASTAc/02: Thu 14:00–15:40 D29/347-RCX2

ASTAc/03: Thu 15:50–17:30 D29/347-RCX2

ASTAc/04: Thu 15:50–17:30 D29/347-RCX2 **Prerequisites**- None - basic course.
**Course Enrolment Limitations**- The course is also offered to the students of the fields other than those the course is directly associated with.
**fields of study / plans the course is directly associated with**- Biomedicínská technika a bioinformatika (programme LF, C-CV)
- Laboratory Assistant (programme LF, B-SZ)

**Course objectives**- The course is basic introduction into practical data analysis for students of biology and clinical study specialisations. The course accompanies lectures of Bi5040 Biostatistics and shows the computation of presented methods on PC using statistical software (descriptive statistics, one sample and two sample tests, categorical data analysis, ANOVA, correlation and regression analysis, data visualisation, basics of experimental design).
**Learning outcomes**- The students will be able after the course to use the folowing data analysis methods:

Descriptive statistics, data visualisation.

Tables of distribution functions.

Introduction to sampling design and experimental design.

Distribution of continuous and bivariate variables.

Application of binomial distribution in biology.

One sample testing.

Two sample testing.

Application of goodness-of-fit test in biology.

Analysis of variance (ANOVA), non - parametric ANOVA.

Corelation, linear regression. **Syllabus**- Introduction to statistics, testing of hypotheses.
- Tables of distribution functions. Sampling from biological populations, data processing.
- Introduction to sampling design. Continuous, ordinal and nominal data in biology.
- Distribution of continuous and bivariate variables - testing of hypotheses, graphical methods.
- Application of binomial and Poisson distribution in biology.
- One sample testing: sample mean, median, standard deviation, variance, binomial p and Poisson constant.
- Two sample testing. Experimental design - randomized and blocked. Parametric and non - parametric methods.
- Application of goodness-of-fit test in biology, analysis of R x C contingency tables, discrimination of categorical data.
- Measures of similarity in ecology (covariance, correlation coefficients, similarity coefficients).
- Analysis of variance (ANOVA): one-way and two-way model.
- Simple linear regression. Linear regression. Introduction to multivariate linear regression.
- Experimental design: one-way and two-way models; factorial design, randomized blocks. Laboratory and field trials. Nested design of ANOVA in genetics and ecology. Non - parametric ANOVA.

**Literature**- Zar, J.H. (1998) Biostatistical analysis. Prentice Hall, London. 4th ed.
- Sokal, R.R., Rohlf, F.J. (1994) Biometry, W. H. Freeman, 3th ed.
- Petrie, A., Watson, P. (2006) Statistics for Veterinary and Animal Science, Wiley-Blackwell; 2nd ed

**Teaching methods**- Practical training using computers
**Assessment methods**- Exam on computers based on correct application of statistical methods on example data.
**Language of instruction**- Czech
**Further Comments**- Study Materials
**Teacher's information**- http://www.cba.muni.cz/vyuka/

- Enrolment Statistics (Autumn 2017, recent)
- Permalink: https://is.muni.cz/course/med/autumn2017/ASTAc