LF:BVPF0422c Pathophys. II - pract.train. - Course Information
BVPF0422c Pathophysiology II - practical trainingFaculty of Medicine
- Extent and Intensity
- 0/2/0. 1 credit(s). Type of Completion: z (credit).
Taught in person.
- prof. MUDr. Kateřina Kaňková, Ph.D. (lecturer), prof. MUDr. Anna Vašků, CSc. (deputy)
MUDr. Kamil Ďuriš, Ph.D. (seminar tutor)
Mgr. David Galuška (seminar tutor)
Ing. Hana Holcová Polanská, Ph.D. (seminar tutor)
Mgr. Katarína Chalásová, Ph.D. (seminar tutor)
MUDr. Jan Máchal, Ph.D. (seminar tutor)
Mgr. Lukáš Pácal, Ph.D. (seminar tutor)
prof. RNDr. Monika Pávková Goldbergová, Ph.D. (seminar tutor)
Mgr. Jana Šístková, Ph.D. (seminar tutor)
Mgr. Lucie Štrublová (seminar tutor)
Věra Ježková (assistant)
- Guaranteed by
- prof. MUDr. Kateřina Kaňková, Ph.D.
Department of Pathophysiology - Theoretical Departments - Faculty of Medicine
Contact Person: MVDr. Halina Matějová
Supplier department: Department of Pathophysiology - Theoretical Departments - Faculty of Medicine
- Prerequisites (in Czech)
- BVPF0321p Pathophysiology I - lecture
- Course Enrolment Limitations
- The course is only offered to the students of the study fields the course is directly associated with.
- fields of study / plans the course is directly associated with
- Course objectives
- Introduction - "Evidence based medicine"/Use of enzyme (and other) markers in diagnostics of selected pathophysiological states – evaluation of LDH isoenzymes /Exp. induced anaphylactic response in lab. animal (part 1)/Exp. induced anaphylactic response in lab. animal (part 2)/Experimentally induced peptic ulcer in the rat. Examination of the gastric juice in the rat/ Exp. induced diabetes mellitus – diagnostic by oral glucose tolerance test/ Overview of molecular biology exp. methods used in pathophysiology (demonstration of selected lab. methods), principles of DNA diagnostics (part 1) – detection of polymorphism in the leptin gene by PCR /Principles of DNA diagnostics (part 2) – electrophoresis of the PCR products/Essential hypertension, resting and ambulatory blood pressure (and heart rate) measurements, postural changes, effect of isometric and aerobic exercise/ Eating disorders - evaluation of nutritional status and energy metabolism.
- Learning outcomes
- After completing the course student will be able:
- to perform practically selected clin. examinations and tests;
- to explain principles of molecular-biology diagnostics;
- to discuss advantages and limitations of experimental animal models in biomedical science.
- Epigenetics and environmental impact in the context of pathophysiology. Pharmacogenomics.
- Overview of molecular biology methods used in pathophysiology, the importance and principles of DNA diagnostics.
- Exp. induced diabetes mellitus - evidence by glucose tolerance test.
- Nutrition in diabetes mellitus, obesity in children (case report analysis).
- Pathophysiology of adipose tissue. Eating disorders, obesity, starvation, malnutrition, catabolic states, mental anorexia and bulimia, tumor anorexia / cachexia (seminar) - practical demonstration of nutritional status assessment.
- Essential hypertension (seminar), one-time examination and outpatient monitoring of blood pressure, SF and their changes during isometric and light aerobic exercise.
- Spirometric examination and dopplerometry.
- Radiation damage, microscopy.
- Enzyme and other markers used in the diagnosis of selected pathological conditions, credit.
- Teaching methods
- practical exercise
- Assessment methods
- Participation in practical exercises is obligatory (excuse only on the basis of incapacity for work). Teaching is completed by credit, subject to full attendance, and optionally other individual criteria chosen by the teacher.
- Language of instruction
- Further comments (probably available only in Czech)
- The course is taught annually.
The course is taught: every week.
Information on the extent and intensity of the course: 30.
- Teacher's information