FAAI1_15 Analytical Chemistry I

Faculty of Pharmacy
Autumn 2025
Extent and Intensity
2/3/0. 4 credit(s). Type of Completion: z (credit).
In-person direct teaching
Teacher(s)
doc. RNDr. Bc. Jiří Pazourek, Ph.D. (lecturer)
doc. RNDr. Bc. Jiří Pazourek, Ph.D. (seminar tutor)
Mgr. Tomáš Crha (seminar tutor)
Ing. Klára Odehnalová, Ph.D. (seminar tutor)
Bc. Gabriela Jelínková (assistant)
Guaranteed by
doc. RNDr. Bc. Jiří Pazourek, Ph.D.
Department of Chemical Drugs – Departments – Faculty of Pharmacy
Timetable
Thu 11:50–13:30 44-247
  • Timetable of Seminar Groups:
FAAI1_15/01: each odd Thursday 13:30–18:30 44-339, T. Crha, K. Odehnalová, J. Pazourek
Prerequisites (in Czech)
STUDIJNI_SKUPINA(start_before_2025)
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Objective of the course - aims of the course unit: To provide theoretical and practical knowledge for qualified chemical and instrumental analysis of inorganic and organic substances, including drugs, emphasizing the importance of methods in drug analysis and studying structural and physicochemical properties of substances related to their biological effect. Emphasis is placed on the formation of logical thought processes of the pharmacist important for his future professional application. In practical exercises, mastering work habits and independent approach of students to solving analytical problems is consistently required.
Learning outcomes
After completing the course, the student will be able to: - understand the meaning and principles of classical and modern analytical chemistry - have an overview of methods of qualitative analytical chemistry - practically perform basic laboratory tests of qualitative analytical chemistry
Syllabus
Content of the lectures 1.-3. Analytical chemistry: The goal and basic terms of the science, methods. Analytical reactions: protolytic, redox, precipitation and complexation reactions. Importance of pH. Qualitative analysis of inorganic compounds. Group reactions of cations. Group reactions of anions. Selective and specific reactions of selected pharmaceutically important ions. 4.-5. Qualitative analysis of organic compounds. Classical proofs and identification. Preliminary test. Classes of solubility. Elemental analysis. Identification of organic compounds: Proofs of functional groups. Determination of basic physical constants, precise measurement of pH. 6.-9. Qualitative analysis of organic compounds. Instrumental methods of structure analysis UV-VIS, IR, examples 10.-12. Qualitative analysis of organic compounds. Instrumental methods of structure analysis NMR, MS, examples Content of the laboratory exercises 1.+2. Organization of the exercises. Safety rules in the chemical laboratory. Group and selective reactions of cations: group reagents HCl, NaOH, NH3. Analysis of an unknown sample. 3.+4. Group and selective reactions of anions, group reagents: BaCl2, AgNO3. Analysis of an unknown sample. 5.+6. Elemental analysis, confirmation of important functional groups: alcohol, aldehydes, carboxylic acids, amines. Preliminary test, determination of the solubility class. Analysis of unknown samples. 7.+8. Refractive index measurement, determination of melting point. pH measurement - determination of a weak acid 9.+10. UV-VIS qualitative analysis of organic compounds. Analysis of an unknown sample from a UV-VIS spectrum. Spectrum of an acid-base indicator in acidic and basic pH. 11.+12. IR qualitative analysis of organic compounds. Transmission and reflection modes (ATR). Analysis of an unknown sample.
Literature
    required literature
  • Skoog, West. Fundamentals of Analytical Chemistry. URL, URL info
    recommended literature
  • European Pharmacopoeia. URL, URL info
Teaching methods
Monologic (reading, lessons, demonstration) Laboratory work
Assessment methods
To get credits a student must: -take part in all the laboratory exercises -submit protols from all the laboratory exercises -51% of correct answers of a final credit test
Language of instruction
English
Further Comments
Study Materials
The course can also be completed outside the examination period.
Listed among pre-requisites of other courses
Teacher's information
https://moodlinka.ics.muni.cz
The course is also listed under the following terms Autumn 2020, Autumn 2021, Autumn 2022, Autumn 2023, Autumn 2024.
  • Enrolment Statistics (recent)
  • Permalink: https://is.muni.cz/course/pharm/autumn2025/FAAI1_15