ZLFA0621c Pharmacology I - practice

Faculty of Medicine
Spring 2016
Extent and Intensity
0/1/0. 2 credit(s). Type of Completion: z (credit).
Teacher(s)
doc. MUDr. Regina Demlová, Ph.D. (lecturer)
doc. PharmDr. Jan Juřica, Ph.D. (lecturer)
MUDr. Jana Nováková, Ph.D. (lecturer)
MUDr. Jana Vinklerová, Ph.D., MBA (seminar tutor)
MUDr. Jana Pistovčáková, Ph.D. (lecturer)
doc. PharmDr. Ondřej Zendulka, Ph.D. (lecturer)
MUDr. Alena Máchalová, Ph.D. (lecturer)
doc. PharmDr. Jana Rudá, Ph.D. (lecturer)
doc. Mgr. MVDr. Leoš Landa, Ph.D. (seminar tutor)
Mgr. Irena Babilonová (seminar tutor)
PharmDr. Lenka Součková, Ph.D. (seminar tutor)
Mgr. Petra Amchová, Ph.D. (seminar tutor)
Anas Arab, Ph.D. (seminar tutor)
MVDr. Zuzana Babinská, Ph.D. (seminar tutor)
MVDr. Eva Dražanová, Ph.D. (seminar tutor)
Mgr. Hana Kostková (seminar tutor)
Mgr. Jana Kubátová, Ph.D. (seminar tutor)
Dr. Vincenzo Micale, Ph.D. (seminar tutor)
Mgr. Kristýna Nosková, Ph.D. (seminar tutor)
Mgr. Gabriela Přibyl Dovrtělová, Ph.D. (seminar tutor)
MUDr. Petra Řiháčková, MBA (seminar tutor)
Mgr. Barbora Říhová, Ph.D. (seminar tutor)
PharmDr. Irena Sehnalová, Ph.D. (seminar tutor)
MUDr. Mgr. Karel Šlais, Ph.D. (seminar tutor)
Mgr. Tibor Štark (seminar tutor)
PharmDr. Miroslav Turjap, Ph.D. (seminar tutor)
Renata Bláblová (assistant)
Guaranteed by
doc. MUDr. Regina Demlová, Ph.D.
Department of Pharmacology - Theoretical Departments - Faculty of Medicine
Contact Person: doc. MUDr. Regina Demlová, Ph.D.
Supplier department: Department of Pharmacology - Theoretical Departments - Faculty of Medicine
Timetable of Seminar Groups
ZLFA0621c/21: Mon 21. 3. 7:30–12:45 A19/231, Tue 22. 3. 8:00–13:15 A19/231, Wed 23. 3. 7:30–12:45 A19/231, Thu 24. 3. 7:30–12:45 A19/231, Fri 25. 3. 8:00–13:15 A19/231
ZLFA0621c/22: Mon 7. 3. 7:30–12:45 A19/231, Tue 8. 3. 8:00–13:15 A19/231, Wed 9. 3. 7:30–12:45 A19/231, Thu 10. 3. 7:30–12:45 A19/231, Fri 11. 3. 8:00–13:15 A19/231
ZLFA0621c/23: Mon 4. 4. 7:30–12:45 A19/231, Tue 5. 4. 8:00–13:15 A19/231, Wed 6. 4. 7:30–12:45 A19/231, Thu 7. 4. 7:30–12:45 A19/231, Fri 8. 4. 8:00–13:15 A19/231
ZLFA0621c/40: No timetable has been entered into IS.
Prerequisites (in Czech)
ZLPA0521c Pathology I - practice && ZLPF0521c Pathophysiol.I - practice && ZLCP051c Clin. Exam. in Surgery-pract.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
On completion of the course the student will be able to use formally correct terminology belonging to the valid Pharmacopoea in prescription and making of drug dosage forms of both individually prepared and bulk preparations. The student should be able to understand principles of "pharmacological thinking" for choosing a drug, dosing regimen, pharmacokinetic parameter calculation, differences in administration routes and specifics of pediatric and geriatric pharmacotherapy including possible impact of drug-drug interactions.
Syllabus
  • Pharmacology - practical courses

    Dentistry

    Spring semester 2016

  • /1/
  • INTRODUCTION TO THE STUDY OF PHARMACOLOGY
  • Contents of the study of Pharmacology, contents and organization of theoretical and practical courses and lectures, required and recommended textbooks. The conditions for granting the credit. Pharmacology - definition, basic terminology, subspecializations, drug nomenclature. Introduction to the prescription terminology. Classification of drug preparations. Pharmacopoea, Pharmacopoea Bohemica.
  • INTRODUCTION TO THE PHARMACOKINETICS
  • Transport of drugs across biological barriers. Basic pharmacokinetic processes. Pharmacokinetic parameters. Pharmacokinetics of single and repeated intravascular and extravascular drug administration. Therapeutic drug monitoring (therapeutic monitoring of drug plasmatic concentrations).
  • /2/
  • GENERAL RULES OF THE DRUG PRESCRIPTION
  • Medical prescription and its essentials. Prescription of drugs. Legislation of drug prescription. Work with various handbooks and databases (SÚKL database, Pharmindex, AISLP etc.). Prescription and provisions of narcotic and psychotropic substances.
  • PRESCRIPTION OF READY MADE PREPARATIONS – practice. SOLID DRUG DOSAGE FORMS
  • Prescription of selected drug forms (solid drug dosage forms – powders, capsules, tablets, suppositories).
  • /3/
  • FLUID DRUG DOSAGE FORMS
  • Prescription of selected drug forms (fluid drug dosage forms - solutions for rubbing, compresses and lavages, solutions and drops for oral administration).
  • SOFT AND MELTING DRUG DOSAGE FORMS
  • Prescription of selected drug forms (soft and melting drug dosage forms – ointments, creams, pastes, gels and other preparations for application to the skin and mucous membranes).
  • SPECIAL PRESCRIPTION OF INDIVIDUALLY PREPARED DRUGS USED IN STOMATOLOGY (mucoadhesive pastes, solutions, suspensions, gels, ointments, pastes).
  • /4/
  • PRESCRIPTION TEST (PRESCRIPTION OF INDIVIDUALLY PREPARED AND READY MADE PREPARATIONS)
  • PHARMACOLOGY OF PERIPHERAL NERVOUS SYSTEM - introduction
  • Terminology, neurotransmissions in peripheral nervous system, adrenergic and cholinergic receptors, agonists and antagonists. Functional importance and possibilities of pharmacological affection of sympathetic and parasympathetic system.
  • NORADRENERGIC (SYMPATHETIC) DRUGS - introduction
  • Receptors of noradrenergic (sympathetic) system, pharmacology of drugs activating and blocking noradrenergic (sympathetic) system.
  • /5/
  • MULTIPLE CHOICE FINAL (CREDIT) TEST OF PHARMACOLOGY (MCHQ - topics lessons from days 1 to 4)
  • NORADRENERGIC (SYMPATHETIC) DRUGS - completion
  • Receptors of noradrenergic (sympathetic) system, pharmacology of drugs activating and blocking noradrenergic (sympathetic) system.
  • CHOLINERGIC (PARASYMPATHETIC) DRUGS
  • Receptors of cholinergic (parasympathetic) system, pharmacology of drugs activating and blocking cholinergic (parasympathetic) system.
  • CREDITS
Literature
    required literature
  • NOVÁKOVÁ, Jana, Barbora ONDRÁČKOVÁ and Alexandra ŠULCOVÁ. Základy receptury léčivých přípravků pro praktická cvičení z farmakologie - obor Zubní lékařství. Brno: Multimediální podpora výuky klinických a zdravotnických oborů: Portál Lékařské fakulty Masarykovy univerzity, 2010. 96 pp. ISSN 1801-6103. URL info
  • LINCOVÁ, Dagmar and Hassan FARGHALI. Základní a aplikovaná farmakologie. 2., dopl. a přeprac. vyd. Praha: Galén, 2007. xxiv, 672. ISBN 9788072623730. info
  • ZELENKOVÁ, Olga and Alexandra ŠULCOVÁ. Speciální stomatologická receptura pro praktická cvičení z farmakologie (Special stomatological prescriptions for practicals in pharmacology). 2. přepracované vydání. Brno: Masarykova univerzita v Brně, 2000. 30 pp. ISBN 80-210-2433-X. info
  • http://portal.med.muni.cz/clanek-461-farmakovigilance-a-propagace-leciv.html
  • https://is.muni.cz/auth/el/1411/podzim2008/ZLFA0722p/um/Zasady_antibioticke_ lecby.pdf?fakulta=1411;obdobi=4343;kod=ZLFA0722p
    recommended literature
  • ŠULCOVÁ, Alexandra. Poznámky k přednáškám z farmakologie. 1. vyd. Brno: Masarykova univerzita, 1993. 97 s. ISBN 80-210-0640-4. info
  • DOSTÁLEK, Miroslav, Jan JUŘICA, Eva JANOŠTÍKOVÁ and Lucia ZAHRADNÍKOVÁ. Farmakokinetika (Pharmacokinetics). ČR: Grada, 2006. 220 pp. Farmacie a farmakologie. ISBN 80-247-1464-7. info
  • http://portal.med.muni.cz/modules.php?name=News&file=article&sid=367
  • RANG, H. P. Rang and Dale's pharmacology. 6th ed. [S.l.]: Churchill Livingstone, 2007. xiii, 829. ISBN 9780443069116. info
  • Ritter, James M. - Lewis, Lionel D. - Mant, Timothy G.K. - Ferro, Albert. A Textbook of Clinical Pharmacology and Therapeutics, 5th Ed., Hodder Arnold, 2008. 465 s. ISBN 978-0-340-90046-8
  • Pharmaceutical Practice, 3rd Ed. Winfield, A.J. & Richards, R.M.E., eds. Churchill Livingstone, 2004, ISBN 0443 07206 X
  • HOWLAND, Richard D. and Mary Julia MYCEK. Pharmacology. 3rd ed. Philadelphia: Lippincott Williams & Wilkins, 2006. vii, 552. ISBN 0781741181. info
  • https://is.muni.cz/auth/el/1411/jaro2009/VLFA0621c/um/Practicals_in_Pharmacology_ENGL.pdf?fakulta=1411;obdobi=4504;kod=VLFA0621c
    not specified
  • Český lékopis 2009. Praha: Grada, 2011. 1 DVD-ROM. ISBN 8594049240180. info
Teaching methods
Practicals, the teaching process of include theoretical setting up as well as practical training of knowledge and skills stated in Syllabus. Included are also individual work with specific pharmacological softwares and homeworks on the selected topics, presented and discussed afterward in class.
Assessment methods
The participation in practicals is obligatory and registered. To get credits a student has to pass the multiple-choice test on knowledge of topics taught. More than half correctly answered questions (usually from 20) are required.
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course is taught annually.
Listed among pre-requisites of other courses
The course is also listed under the following terms Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, Spring 2013, Spring 2014, Spring 2015, Spring 2017, Spring 2018, spring 2019, spring 2020, spring 2021.
  • Enrolment Statistics (Spring 2016, recent)
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