aVLBI0222p Medical Biology II - lecture

Faculty of Medicine
spring 2021
Extent and Intensity
2/0/0. 3 credit(s). Type of Completion: zk (examination).
Taught online.
Teacher(s)
prof. RNDr. Ondřej Slabý, Ph.D. (lecturer)
prof. MUDr. David Šmajs, Ph.D. (lecturer)
prof. MUDr. Iva Slaninová, Ph.D. (lecturer)
Mgr. Stjepan Uldrijan, CSc. (lecturer)
Mgr. Vladimír Rotrekl, Ph.D. (lecturer)
Mgr. Kateřina Cetkovská, Ph.D. (seminar tutor)
Ing. Lívia Eiselleová, Ph.D. (seminar tutor)
Mgr. Kateřina Francová, Ph.D. (seminar tutor)
Mgr. Jiří Šána, Ph.D. (seminar tutor)
Jana Růžičková (assistant)
Guaranteed by
prof. RNDr. Ondřej Slabý, Ph.D.
Department of Biology - Theoretical Departments - Faculty of Medicine
Contact Person: Mgr. Kateřina Cetkovská, Ph.D.
Supplier department: Department of Biology - Theoretical Departments - Faculty of Medicine
Timetable
Mon 1. 3. to Thu 27. 5. Thu 10:00–11:40 B11/114
Prerequisites
aVLBI0121c Biology I - pract.
Knowledge of high-school biology and all previous lectures and practical classes of the subject are prerequisites for studying the course. Expected knowledge for each lecture is specified in the course syllabus. The literature recommended to study for each lecture is detailed in the interactive syllabus of the course.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
there are 6 fields of study the course is directly associated with, display
Course objectives
The main objectives of the course are:
- understanding of the basic principles of human genetics
- understanding of the mechanisms of cancer development
- acquaintance with the basics of genomics, immunogenetics, epigenetics, gene therapy, tissue engineering and evolutionary biology
Learning outcomes
After completing the course, the student will be able to:
- explain and apply basic principles of human genetics
- explain the role of medical biology in the development of modern therapies (e.g. molecular therapies of cancer)
- explain the basic principles of current methods used in gene therapy and cell therapies
- understand the significance of the human microbiome in human health and disease
- be knowledgeable in basic modern approaches to studying various diseases and to personalised medicine (genomics)
Syllabus
  • Introduction to Genetics I – Genetics in Medicine, Mendelian Inheritance, Autosomal and Gonosomal Inheritance
  • Introduction to Genetics II – Non-Mendelian Inheritance, Population Genetics
  • Human Genome and Genomics
  • Epigenetics – Interaction of Genes and Environment
  • Immunogenetics
  • Cancer Biology I – Carcinogenesis, Hallmarks of Cancer
  • Cancer Biology II – Application of Cancer Biology into Cancer Diagnostics and Therapy
  • Bacterial and Viral Genomics
  • Discovering the Structure and Function of Genes
  • Gene Therapy
  • Human Microbiome
  • Stem Cells and Tissue Engineering
  • Evolutionary Biology
Literature
    required literature
  • ALBERTS, Bruce, Karen HOPKIN, Alexander JOHNSON, David Owen MORGAN, Martin C. RAFF, Keith ROBERTS and Peter WALTER. Essential cell biology. International student editio. New York: W.W Norton, 2019. xxxii, 734. ISBN 9780393680393. info
  • SNUSTAD, D. Peter and Michael J. SIMMONS. Principles of genetics. Sixth edition. Hoboken: John Wiley & Sons, 2012. xviii, 766. ISBN 9780470903599. info
Teaching methods
lecture every week
Assessment methods
The course of Medical Biology II builds on the knowledge gained from Medical Biology I, and is completed with an oral exam.
Language of instruction
English
Follow-Up Courses
Further comments (probably available only in Czech)
The course is taught annually.
Information on the extent and intensity of the course: 30.
Listed among pre-requisites of other courses
Teacher's information
https://is.muni.cz/auth/el/1411/jaro2021/aVLBI0222p/index.qwarp
Lectures take place every week. We recommend to follow the Interactive syllabus of the course where students can find all relevant information (schedule, substitutions, public holidays etc.), and also corresponding study literature for each week, and links to animations and videos relevant to the topic (https://is.muni.cz/auth/el/1411/jaro2021/aVLBI0222p/index.qwarp)
The course is also listed under the following terms Spring 2016, Spring 2017, Spring 2018, spring 2019, spring 2020.

aVLBI0222p Biology II - lecture

Faculty of Medicine
spring 2020
Extent and Intensity
1/0/0. 4 credit(s). Type of Completion: zk (examination).
Teacher(s)
Mgr. Kateřina Cetkovská, Ph.D. (lecturer)
Ing. Lívia Eiselleová, Ph.D. (lecturer)
Mgr. Kateřina Francová, Ph.D. (lecturer)
Mgr. Vladimír Rotrekl, Ph.D. (lecturer)
prof. RNDr. Ondřej Slabý, Ph.D. (lecturer)
prof. MUDr. Iva Slaninová, Ph.D. (lecturer)
prof. MUDr. David Šmajs, Ph.D. (lecturer)
Mgr. Stjepan Uldrijan, CSc. (lecturer)
Jana Růžičková (assistant)
Mgr. Kateřina Straková, Ph.D. (alternate examiner)
Guaranteed by
prof. MUDr. David Šmajs, Ph.D.
Department of Biology - Theoretical Departments - Faculty of Medicine
Contact Person: Ing. Lívia Eiselleová, Ph.D.
Supplier department: Department of Biology - Theoretical Departments - Faculty of Medicine
Timetable
Mon 17. 2. to Thu 7. 5. Thu 8:00–8:50 B22/116 aula
Prerequisites
aVLBI0121c Biology I - pract. && aVLBI0121s Biology I - seminar
Knowledge of high-school biology and all previous lectures and practical classes of the subject are prerequisites for studying the course. Expected knowledge for each lecture is specified in the course syllabus. The literature recommended for studying before each lecture is detailed in the interactive syllabus of the course.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The main objectives of the course are:
- understanding the mechanisms of cancer development
- understanding the complex taking place during human embryonic development
- acquaintance with the basics of genomics, gene therapy and tissue engineering in current medicine
Learning outcomes
After completing the course, the student will be able to:
- explain the nature of cancers with regard to deregulation of cell division, DNA repair and cell death
- explain the effects of some therapies with emphasis on modern medicine (molecular therapies of cancer)
- explain the elementary processes taking place during the development of a human body
- express the basic coherence between malfunction in these processes and developmental defects
- explain the basic principles of current methods used in gene therapy and cell therapies
- understand the significance of the human microbiome composition
- be knowledgeable in basic modern approaches to studying various diseases and to personalised medicine (genomics, bioinformatics)
Syllabus
  • DNA damage and repair – from molecular mechanisms to clinical significance
  • Introduction to cancer biology
  • Oncogenes and oncoviruses in cancer transformation
  • Tumour suppressor genes and their significance for diagnostics and therapy
  • Paradigm of cancer stem cells and implications for anti-cancer therapies
  • Gene therapy – targets and strategies of molecular therapies
  • Stem cells and tissue engineering – prospects of regenerative medicine
  • From a single cell to human I – introduction to developmental biology
  • From a single cell to human II – molecular basis of mammalian development in health and disease
  • Human genome, genomics and bioinformatics in current biomedicine
  • Human microbiome
  • Modern approaches in studying macromolecules and their use in current biomedicine
Literature
    required literature
  • ALBERTS, Bruce. Essential cell biology. 4th edition. New York, N.Y.: Garland Science, 2014. xxiii, 726. ISBN 9780815344551. info
  • Medical genetics at a glance. Edited by D. J. Pritchard - Bruce R. Korf. 3rd ed. Chichester, England: Wiley-Blackwell, 2013. 1 online r. ISBN 9781118689028. info
Teaching methods
lecture every week
Assessment methods
Lecture attendance is optional. The course of Biology II builds on the knowledge gained from Biology I, and is completed with a written examination test taken on computers. The test contains questions based on the topics discussed in the lectures, seminars and practices of both semesters. The students are expected to be able to autonomously solve assigned problems and to derive the solutions using their own thinking – based on the theory discussed during both semesters and supplemented by the recommended reading. The test contains 60 questions in total; at least 30 points are needed to pass.
Language of instruction
English
Follow-Up Courses
Further comments (probably available only in Czech)
The course is taught annually.
Information on the extent and intensity of the course: 15.
Listed among pre-requisites of other courses
Teacher's information
https://is.muni.cz/auth/el/1411/jaro2020/aVLBI0222p/index.qwarp
The course is also listed under the following terms Spring 2016, Spring 2017, Spring 2018, spring 2019, spring 2021.

aVLBI0222p Biology II - lecture

Faculty of Medicine
spring 2019
Extent and Intensity
1/0/0. 4 credit(s). Type of Completion: zk (examination).
Teacher(s)
prof. Ing. Petr Dvořák, CSc. (lecturer)
Ing. Lívia Eiselleová, Ph.D. (lecturer)
doc. Mgr. Lumír Krejčí, Ph.D. (lecturer)
RNDr. Pavel Krejčí, Ph.D. (lecturer)
Mgr. Vladimír Rotrekl, Ph.D. (lecturer)
prof. RNDr. Ondřej Slabý, Ph.D. (lecturer)
prof. MUDr. Iva Slaninová, Ph.D. (lecturer)
prof. MUDr. David Šmajs, Ph.D. (lecturer)
Mgr. Stjepan Uldrijan, CSc. (lecturer)
Mgr. Kateřina Vopěnková, Ph.D. (lecturer)
Jana Růžičková (assistant)
Mgr. Kateřina Straková, Ph.D. (alternate examiner)
Guaranteed by
prof. Ing. Petr Dvořák, CSc.
Department of Biology - Theoretical Departments - Faculty of Medicine
Contact Person: Mgr. Kateřina Vopěnková, Ph.D.
Supplier department: Department of Biology - Theoretical Departments - Faculty of Medicine
Timetable
Mon 18. 2. to Mon 13. 5. Mon 14:00–14:50 B11/114
Prerequisites
aVLBI0121c Biology I - pract. && aVLBI0121s Biology I - seminar
Knowledge of high-school biology and all previous lectures and practical classes of the subject are prerequisities for studying the course. Expected knowledge for each lecture is specified in the course syllabus. Literature recomended to study before each lecture is detailed in the interactive syllabus of the course.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The main objectives of the course are:
- understanding the mechanisms of cancer development
- understanding the complex taking place during human embryonic development
- acquaintance with the basics of genomics, gene therapy and tissue engineering in current medicine
Learning outcomes
After completing the course the student will be able to:
- explain the nature of cancers with regard to deregulation of cell division, DNA repair and cell death
- explain the effects of some therapies with emphasis on modern medicine (molecular therapies of cancer)
- explain the elementary processes taking place during development of a human body
- express the basic coherence between malfunction in these processes and developmental defects
- explain the basic principles of current methods used in gene therapy and cell therapies
- understand the significance of the human microbiome composition
- be knowledgeable in basic modern approaches to studying various diseases and to personalised medicine (genomics, bioinformatics)
Syllabus
  • DNA damage and repair – from molecular mechanisms to clinical significance
  • Introduction to cancer biology
  • Oncogenes and oncoviruses in cancer transformation
  • Tumour suppressor genes and their significance for diagnostics and therapy
  • Paradigm of cancer stem cells and implications for anti-cancer therapies
  • Gene therapy – targets and strategies of molecular therapies
  • Stem cells and tissue engineering – prospects of regenerative medicine
  • From a single cell to human I – introduction to developmental biology
  • From a single cell to human II – molecular basis of mammalian development in health and disease
  • Human genome, genomics and bioinformatics in current biomedicine
  • Human microbiome
  • Modern approaches in studying macromolecules and their use in current biomedicine
Literature
    required literature
  • ALBERTS, Bruce. Essential cell biology. 4th edition. New York, N.Y.: Garland Science, 2014. xxiii, 726. ISBN 9780815344551. info
  • Medical genetics at a glance. Edited by D. J. Pritchard - Bruce R. Korf. 3rd ed. Chichester, England: Wiley-Blackwell, 2013. 1 online r. ISBN 9781118689028. info
Teaching methods
lecture every week
Assessment methods
Lecture attendance is optional. The course of Biology II builds on knowledge gained from Biology I, and is completed with a written examination test taken on computers. The test contains questions based on the topics discussed in the lectures, seminars and practices of both semesters. The students are expected to be able to autonomously solve assigned problems and to derive the solutions using their own thinking – based on the theory discussed during both semesters and supplemented by the recommended reading. The test contains 60 questions in total; at least 30 points are needed to pass.
Language of instruction
English
Follow-Up Courses
Further comments (probably available only in Czech)
The course is taught annually.
Information on the extent and intensity of the course: 15.
Listed among pre-requisites of other courses
Teacher's information
https://is.muni.cz/auth/el/1411/jaro2018/aVLBI0222p/index.qwarp
The course is also listed under the following terms Spring 2016, Spring 2017, Spring 2018, spring 2020, spring 2021.

aVLBI0222p Biology II - lecture

Faculty of Medicine
Spring 2018
Extent and Intensity
1/0/0. 4 credit(s). Type of Completion: zk (examination).
Teacher(s)
Mgr. Kateřina Cetkovská, Ph.D. (lecturer)
prof. Ing. Petr Dvořák, CSc. (lecturer)
doc. Mgr. Lumír Krejčí, Ph.D. (lecturer)
RNDr. Pavel Krejčí, Ph.D. (lecturer)
Mgr. Vladimír Rotrekl, Ph.D. (lecturer)
prof. MUDr. Iva Slaninová, Ph.D. (lecturer)
Mgr. Kateřina Straková, Ph.D. (lecturer)
prof. MUDr. David Šmajs, Ph.D. (lecturer)
RNDr. Mário Špírek, PhD. (lecturer)
Mgr. Stjepan Uldrijan, CSc. (lecturer)
Mgr. Kateřina Vopěnková, Ph.D. (lecturer)
Ing. Lívia Eiselleová, Ph.D. (seminar tutor)
Mgr. Kateřina Straková, Ph.D. (seminar tutor)
Jana Růžičková (assistant)
Guaranteed by
prof. Ing. Petr Dvořák, CSc.
Department of Biology - Theoretical Departments - Faculty of Medicine
Contact Person: Mgr. Kateřina Cetkovská, Ph.D.
Supplier department: Department of Biology - Theoretical Departments - Faculty of Medicine
Timetable
Mon 19. 2. to Fri 18. 5. Wed 13:05–13:55 B11/334
Prerequisites
aVLBI0121c Biology I - pract. && aVLBI0121s Biology I - seminar
Knowledge of high-school biology and all previous lectures and practical classes of the subject are prerequisities for studying the course. Expected knowledge for each lecture is specified in the course syllabus. Literature recomended to study before each lecture is detailed in the interactive syllabus of the course.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The main objectives of the course are:
- understanding the mechanisms of cancer development
- understanding the complex taking place during human embryonic development
- acquaintance with the basics of genomics, gene therapy and tissue engineering in current medicine
Learning outcomes
After completing the course the student will be able to:
- explain the nature of cancers with regard to deregulation of cell division, DNA repair and cell death
- explain the effects of some therapies with emphasis on modern medicine (molecular therapies of cancer)
- explain the elementary processes taking place during development of a human body
- express the basic coherence between malfunction in these processes and developmental defects
- explain the basic principles of current methods used in gene therapy and cell therapies
- understand the significance of the human microbiome composition
- be knowledgeable in basic modern approaches to studying various diseases and to personalised medicine (genomics, bioinformatics)
Syllabus
  • DNA damage and repair – from molecular mechanisms to clinical significance
  • Introduction to cancer biology
  • Oncogenes and oncoviruses in cancer transformation
  • Tumour suppressor genes and their significance for diagnostics and therapy
  • Paradigm of cancer stem cells and implications for anti-cancer therapies
  • Gene therapy – targets and strategies of molecular therapies
  • Stem cells and tissue engineering – prospects of regenerative medicine
  • From a single cell to human I – introduction to developmental biology
  • From a single cell to human II – molecular basis of mammalian development in health and disease
  • Human genome, genomics and bioinformatics in current biomedicine
  • Human microbiome
  • Modern approaches in studying macromolecules and their use in current biomedicine
Literature
    required literature
  • ALBERTS, Bruce. Essential cell biology. 4th edition. New York, N.Y.: Garland Science, 2014. xxiii, 726. ISBN 9780815344551. info
  • Medical genetics at a glance. Edited by D. J. Pritchard - Bruce R. Korf. 3rd ed. Chichester, England: Wiley-Blackwell, 2013. 1 online r. ISBN 9781118689028. info
Teaching methods
lecture every week
Assessment methods
Lecture attendance is optional. The course of Biology II builds on knowledge gained from Biology I, and is completed with a written examination test taken on computers. The test contains questions based on the topics discussed in the lectures, seminars and practices of both semesters. The students are expected to be able to autonomously solve assigned problems and to derive the solutions using their own thinking – based on the theory discussed during both semesters and supplemented by the recommended reading. The test contains 60 questions in total; at least 30 points are needed to pass.
Language of instruction
English
Follow-Up Courses
Further comments (probably available only in Czech)
The course is taught annually.
Listed among pre-requisites of other courses
Teacher's information
https://is.muni.cz/auth/el/1411/jaro2018/aVLBI0222p/index.qwarp
The course is also listed under the following terms Spring 2016, Spring 2017, spring 2019, spring 2020, spring 2021.

aVLBI0222p Biology II - lecture

Faculty of Medicine
Spring 2017
Extent and Intensity
1/0. 4 credit(s). Type of Completion: zk (examination).
Teacher(s)
Mgr. Kateřina Cetkovská, Ph.D. (lecturer)
prof. Ing. Petr Dvořák, CSc. (lecturer)
doc. Mgr. Lumír Krejčí, Ph.D. (lecturer)
RNDr. Pavel Krejčí, Ph.D. (lecturer)
Mgr. Vladimír Rotrekl, Ph.D. (lecturer)
prof. MUDr. Iva Slaninová, Ph.D. (lecturer)
prof. MUDr. David Šmajs, Ph.D. (lecturer)
RNDr. Mário Špírek, PhD. (lecturer)
Mgr. Stjepan Uldrijan, CSc. (lecturer)
Mgr. Kateřina Vopěnková, Ph.D. (lecturer)
Jana Růžičková (assistant)
Mgr. Kateřina Straková, Ph.D. (assistant)
Mgr. Martina Vráblíková (assistant)
Guaranteed by
prof. Ing. Petr Dvořák, CSc.
Department of Biology - Theoretical Departments - Faculty of Medicine
Contact Person: Mgr. Kateřina Cetkovská, Ph.D.
Supplier department: Department of Biology - Theoretical Departments - Faculty of Medicine
Timetable
Mon 22. 5. to Fri 26. 5. Wed 13:00–15:50 B09/324, Mon 20. 2. to Fri 19. 5. Wed 13:05–13:55 B11/334; and Wed 24. 5. 13:05–13:55 B11/235
Prerequisites
aVLBI0121c Biology I - pract. && aVLBI0121s Biology I - seminar
Knowledge of high-school biology and all previous lectures and practical classes of the subject are prerequisities for studying the course. Expected knowledge for each lecture is specified in the course syllabus. Literature recomended to study before each lecture is detailed in the interactive syllabus of the course.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
After completion of the course student: understands elementary cellular processes and processes taking place during development of a human body; comprehends the complexity of intercellular communication and mutual regulation of individual cells in a multicellular organism; knows basic principles of bacterial and viral diseases; is able to express basic coherence between malfunction in cellular processes and development of diseases, especially hereditary diseases, cancers or developmental defects, and understands the principle of genetic determination of hereditary diseases; can explain and justify action of some therapeutics with emphasis on modern medicine. Student is also able to apply this knowledge and skills in other subject, especially physiology, pathophysiology and human genetics.
Learning outcomes
After completion of the course student: understands elementary cellular processes and processes taking place during development of a human body; comprehends the complexity of intercellular communication and mutual regulation of individual cells in a multicellular organism; knows basic principles of bacterial and viral diseases; is able to express basic coherence between malfunction in cellular processes and development of diseases, especially hereditary diseases, cancers or developmental defects, and understands the principle of genetic determination of hereditary diseases; can explain and justify action of some therapeutics with emphasis on modern medicine. Student is also able to apply this knowledge and skills in other subject, especially physiology, pathophysiology and human genetics.
Syllabus
  • 1. week:
  • DNA damage and repair – from molecular mechanisms to clinical significance (doc. Mgr. Lumír Krejčí, Ph.D.)
  • 2. week:
  • Introduction to cancer biology (Mgr. Stjepan Uldrijan, CSc.)
  • 3. week:
  • Oncogenes and oncoviruses in cancer transformation (Mgr. Stjepan Uldrijan, CSc.)
  • 4. week:
  • Tumour suppressor genes and their significance for diagnostics and therapy (Mgr. Stjepan Uldrijan, CSc.)
  • 5. week:
  • Paradigm of cancer stem cells and implications for anti-cancer therapies (doc. MUDr. Iva Slaninová, Ph.D.)
  • 6. týden:
  • Gene therapy – targets and strategies of molecular therapies (doc. MUDr. Iva Slaninová, Ph.D.)
  • 7. week:
  • Stem cells and tissue engineering – prospects of regenerative medicine (prof. Ing. Petr Dvořák, CSc.)
  • 8. week:
  • From a single cell to human I – introduction to developmental biology (Mgr. Vladimír Rotrekl, Ph.D.)
  • 9. week:
  • From a single cell to human II – molecular basis of mammalian development in health and disease (Mgr. Pavel Krejčí, Ph.D.)
  • 10. week:
  • Human genome and genomics in current biomedicine (prof. MUDr. David Šmajs, Ph.D.)
  • 11. week:
  • Human microbiome (prof. MUDr. David Šmajs, Ph.D.)
  • 12. week:
  • Bioinformatics in medicine – from molecules to populations (Mgr. Vladimír Rotrekl, Ph.D.)
  • 13. week:
  • Modern approaches in studying macromolecules and their use in current biomedicine (Mgr. Vladimír Rotrekl, Ph.D.)
  • 14. week:
  • Substitution lecture
Literature
    required literature
  • ALBERTS, Bruce. Essential cell biology. 4th edition. New York, N.Y.: Garland Science, 2014. xxiii, 726. ISBN 9780815344551. info
  • Medical genetics at a glance. Edited by D. J. Pritchard - Bruce R. Korf. 3rd ed. Chichester, England: Wiley-Blackwell, 2013. 1 online r. ISBN 9781118689028. info
    recommended literature
  • HARDIN, Jeff, Gregory BERTONI and Lewis J. KLEINSMITH. Becker's world of the cell. 8th ed. Boston: Benjamin Cummings, 2012. xxviii, 79. ISBN 9780321709783. info
  • LODISH, Harvey F. Molecular cell biology. 6th ed. New York, N.Y.: W.H. Freeman and Company, 2008. xxxvii, 11. ISBN 9780716776017. info
  • SNUSTAD, D. Peter and Michael J. SIMMONS. Principles of genetics. 5th ed. Hoboken: John Wiley & Sons, Inc, 2009. xix, 823. ISBN 9780470388259. info
  • WEINBERG, Robert A. The biology of cancer. Second edition. London: Garland Science, 2013. xx, 876. ISBN 9780815345282. info
  • WOLPERT, L. Principles of development. 2nd ed. Oxford: Oxford University Press, 2002. xxv, 542. ISBN 0198792913. info
    not specified
  • CAMPBELL, Neil A. Biology. Edited by Jane B. Reece. 7th ed. San Francisco: Pearson/Benjamin Cummings, 2005. xl, 1231. ISBN 080537146X. info
Teaching methods
lecture
Assessment methods
The course Biology II builds on knowledge gained from subject Biology I - lecture (aVLBI0121p) and is completed with a written examination test taken on computers. It contains questions based on the topics discussed in the lectures and practices. The students are expected to be able to solve given problems on their own, and to derive the solutions by their own consideration based on the theory discussed in the course of both semesters and supplemented by the recommended reading.
Language of instruction
English
Further comments (probably available only in Czech)
Study Materials
The course is taught annually.
Listed among pre-requisites of other courses
Teacher's information
https://is.muni.cz/auth/el/1411/jaro2017/aVLBI0222p/index.qwarp
The course is also listed under the following terms Spring 2016, Spring 2018, spring 2019, spring 2020, spring 2021.

aVLBI0222p Biology II - lecture

Faculty of Medicine
Spring 2016
Extent and Intensity
1/0. 4 credit(s). Type of Completion: zk (examination).
Teacher(s)
Mgr. Kateřina Cetkovská, Ph.D. (lecturer)
prof. Ing. Petr Dvořák, CSc. (lecturer)
doc. Mgr. Lumír Krejčí, Ph.D. (lecturer)
RNDr. Pavel Krejčí, Ph.D. (lecturer)
Mgr. Vladimír Rotrekl, Ph.D. (lecturer)
prof. MUDr. Iva Slaninová, Ph.D. (lecturer)
prof. MUDr. David Šmajs, Ph.D. (lecturer)
RNDr. Mário Špírek, PhD. (lecturer)
Mgr. Stjepan Uldrijan, CSc. (lecturer)
Mgr. Kateřina Vopěnková, Ph.D. (lecturer)
doc. Yuh-Man Wadeley, Doctor of Philosophy (lecturer)
Jana Růžičková (assistant)
Mgr. Martina Vráblíková (assistant)
Guaranteed by
prof. Ing. Petr Dvořák, CSc.
Department of Biology - Theoretical Departments - Faculty of Medicine
Contact Person: Mgr. Kateřina Cetkovská, Ph.D.
Supplier department: Department of Biology - Theoretical Departments - Faculty of Medicine
Timetable
Wed 13:00–13:50 B11/234
Prerequisites
aVLBI0121c Biology I - pract. && aVLBI0121s Biology I - seminar
Knowledge of high-school biology and all previous lectures and practical classes of the subject are prerequisities for studying the course. Expected knowledge for each lecture is specified in the course syllabus. Literature recomended to study before each lecture is detailed in the interactive syllabus of the course.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
After completion of the course student: understands elementary cellular processes and processes taking place during development of a human body; comprehends the complexity of intercellular communication and mutual regulation of individual cells in a multicellular organism; is able to deduce and explain the difference between healthy and pathologically-working cell; is able to express basic coherence between malfunction in cellular processes and development of diseases, especially hereditary diseases, cancers or developmental defects; can explain and justify action of some therapeutics with emphasis on modern medicine. Student is also able to apply this knowledge and skills in other subject, especially physiology, pathophysiology and human genetics.
Syllabus
  • Week 1: 22.2. – 26.2. 2014
  • Growth factors and signal transduction in development and disease (Mgr. Pavel Krejčí, Ph.D.)
  • Week 2: 29.2. – 4.3.
  • Biology and use of stem cells in disease modelling and cell therapy (prof. Ing. Petr Dvořák, CSc.)
  • Week 3: 7.3. – 11.3.
  • Cell differentiation and tissue engineering (prof. Ing. Petr Dvořák, CSc.)
  • Week 4: 14.3. – 18.3.
  • Genome instability - from molecular mechanisms of damage and DNA repair to clinical implications (doc. Mgr. Lumír Krejčí, Ph.D)
  • Week 5: 21.3. – 25.3.
  • Introduction to cancer biology (Mgr. Stjepan Uldrijan, CSc.)
  • Week 6: 28.3. – 1.4.
  • Oncogenes and oncoviruses in cancer transformation (Mgr. Stjepan Uldrijan, CSc.)
  • Week 7: 4.4. – 8.4.
  • Tumour suppressor genes - implications for diagnostics and therapy (Mgr. Stjepan Uldrijan, CSc.)
  • Week 8: 11.4. – 15.4.
  • Paradigm of cancer stem cells (doc. MUDr. Iva Slaninová, Ph.D.)
  • Week 9: 18.4. – 22.4.
  • Molecular principle of genetically determined diseases (doc. MUDr. Iva Slaninová, Ph.D.)
  • Week 10: 25.4. – 29.4.
  • Objectives and strategies of molecular therapy (doc. MUDr. Iva Slaninová, Ph.D.)
  • Week 11: 2.5. – 6.5.
  • Genomics and other omics in current biomedicine (prof. MUDr. David Šmajs, Ph.D.)
  • Week 12: 9.5. – 13.5.
  • Human microbiome (prof. MUDr. David Šmajs, Ph.D.)
  • Week 13: 16.5. – 20.5.
  • Bioinformatics in medicine - from molecules to populations (Mgr. Vladimír Rotrekl, Ph.D.) - groups not having dissections clashing with the lecture
  • Week 14: 23.5. – 72.5.
  • Bioinformatics in medicine - from molecules to populations (Mgr. Vladimír Rotrekl, Ph.D.) - groups not having dissections clashing with the lecture
Literature
    required literature
  • Essential cell biology. Edited by Bruce Alberts. 3rd ed. New York: Garland Science, 2009. 1 v. ISBN 9780815341307. info
  • Medical genetics at a glance. Edited by D. J. Pritchard - Bruce R. Korf. 3rd ed. Chichester, England: Wiley-Blackwell, 2013. 1 online r. ISBN 9781118689028. info
    recommended literature
  • HARDIN, Jeff, Gregory BERTONI and Lewis J. KLEINSMITH. Becker's world of the cell. 8th ed. Boston: Benjamin Cummings, 2012. xxviii, 79. ISBN 9780321709783. info
  • LODISH, Harvey F. Molecular cell biology. 6th ed. New York, N.Y.: W.H. Freeman and Company, 2008. xxxvii, 11. ISBN 9780716776017. info
  • SNUSTAD, D. Peter and Michael J. SIMMONS. Principles of genetics. 5th ed. Hoboken: John Wiley & Sons, Inc, 2009. xix, 823. ISBN 9780470388259. info
  • WEINBERG, Robert A. The biology of cancer. Second edition. London: Garland Science, 2013. xx, 876. ISBN 9780815345282. info
  • WOLPERT, L. Principles of development. 2nd ed. Oxford: Oxford University Press, 2002. xxv, 542. ISBN 0198792913. info
    not specified
  • CAMPBELL, Neil A. Biology. Edited by Jane B. Reece. 7th ed. San Francisco: Pearson/Benjamin Cummings, 2005. xl, 1231. ISBN 080537146X. info
Teaching methods
lecture
Assessment methods
Subject is completed with a written examination test, based on knowledge of all topics from both semesters (lectures, seminars, practices). The exam test contains 100 questions with 1 correct answer. Negative marking is obtained for incorrect answers. For successful passing the exam, minimum 68 points out of 200 are needed.
Requirements for attendance at the exam: successful passing of the autumn semester’s lecture and seminar, and successfull completion of Biology-practices of both autumn and spring semester.
Students have to bring their valid ICIS card to prove their identity at the exam. For more information on the test see: https://is.muni.cz/auth/el/1411/jaro2016/aVLBI0222p/op/Exam_information_and_instructions_ENG.pdf
Lecture attendance is optional.
Language of instruction
English
Further comments (probably available only in Czech)
Study Materials
The course is taught annually.
Listed among pre-requisites of other courses
Teacher's information
https://is.muni.cz/auth/el/1411/jaro2016/aVLBI0222p/index.qwarp
The course is also listed under the following terms Spring 2017, Spring 2018, spring 2019, spring 2020, spring 2021.
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