aZLBI0121c Biology I - practice

Faculty of Medicine
autumn 2020
Extent and Intensity
0/2/0. 2 credit(s). Type of Completion: z (credit).
Taught in person.
Teacher(s)
prof. RNDr. Ondřej Slabý, Ph.D. (lecturer)
Ing. Lívia Eiselleová, Ph.D. (seminar tutor)
Mgr. Kateřina Cetkovská, Ph.D. (seminar tutor)
prof. MUDr. Iva Slaninová, Ph.D. (lecturer)
Felicity Anne Feiser (seminar tutor)
Mgr. Petr Fojtík (seminar tutor)
Sebastiano Giallongo (seminar tutor)
Monica Medappa (seminar tutor)
Master Alexandru Nită (seminar tutor)
Mgr. Markéta Nováková, Ph.D. (seminar tutor)
Sara Poovakulathu Abraham, MSc (seminar tutor)
Mgr. Petra Pospíšilová, Ph.D. (seminar tutor)
Mgr. Vladimír Rotrekl, Ph.D. (seminar tutor)
Nicola Silva, PhD. (seminar tutor)
prof. MUDr. Iva Slaninová, Ph.D. (seminar tutor)
Mgr. Barbora Valčíková (seminar tutor)
Gretsen Velezmoro Jauregui, M.Sc. (seminar tutor)
Jana Růžičková (assistant)
Guaranteed by
prof. MUDr. Iva Slaninová, Ph.D.
Department of Biology - Theoretical Departments - Faculty of Medicine
Contact Person: Ing. Lívia Eiselleová, Ph.D.
Supplier department: Department of Biology - Theoretical Departments - Faculty of Medicine
Timetable
Wed 12:00–12:30 B07/214, Wed 12:30–13:30 B07/217, Wed 12:30–13:30 B07/214, Wed 13:30–13:40 B07/214
Prerequisites
Knowledge of high-school biology on the level of Overview of High School Biology (https://is.muni.cz/auth/do/med/el/overview/overview_ENG.qwarp) or similar is required.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The main objectives of the course are:
- learning to operate the light microscope while observing prokaryotic and eukaryotic cells and various cell structures and processes
- understanding the methods of risk evaluation for monogenic hereditary diseases with autosomal inheritance in patients based on family anamneses
Learning outcomes
After completing the course the student will be able to:
- operate the light microscope
- perform some of the basic cytochemical staining techniques in observation of bacterial and human cells
- explain the basic principles and use of electron microscopy
- describe the basic techniques and applications of tissue and cell cultures
- deduce the impact of selected DNA mutations on the primary structure of proteins
- explain the methodology of assembling and examining the karyotype and its use, and to evaluate basic numerical and structural aberrations in assigned human karyotypes
- evaluate the risk of numerical and structural aberrations resulting from meiotic non-disjunctions and chromosomal translocations
- evaluate the risk of monogenic hereditary diseases with autosomal inheritance in patients based on assigned family anamneses of the diseases
Syllabus
  • Week 1: Instructions. Non-cellular organisms and infectious agents
  • Week 2: Prokaryotic cells and their medical significance
  • Week 3: Microscopic observation of eukaryotic cells
  • Week 4: In vitro culture of human cells
  • Week 5: Human karyotype and chromosomal abnormalities
  • Week 6: Control test 1 (knowledge of the weeks 1 to 5 - only from practices)
  • Week 7: DNA structure and replication. Transcription and translation
  • Week 8: Genetic toxicology
  • Week 9: Principles of electron microscopy, cellular ultrastructure
  • Week 10: Methods of cell cycle studying
  • Week 11: Mitosis observation in a light microscope
  • Week 12: Biological significance of meiosis - gametogenesis
  • Week 13: Control test 2 (knowledge of the weeks 7 to 12 - only from practices)
  • Week 14: substitution week
Literature
    required literature
  • Actual protocols for practices are provided in electronic form in the Information System of the Masaryk University (IS): Study Materials of the course aZLBI0121c
Teaching methods
laboratory practice, class discussion
Assessment methods
Practical classes are mandatory.
Requirements for course completion: full attendance in the practices (1 absence, excused or unexcused, is allowed); all protocols completed (also for missed lessons) and checked and signed by appropriate teachers; successfully passed practical microscopy exam; successfully passed 2 written control tests during the semester (20 questions each, 4 possibilities, 1 answer correct, student need to reach at least 12 points out of 20 in each test). In case you do not pass one of the control tests, you can do a re-sit.
In case of student’s late arrival to the practice or poor activity at the practice, student is required to write an essay in the length of 2 pages on a given topic. Same for the case of 2nd and any additional absence in practices (excused or unexcused). Find the instructions for essay writing in the Course-related instructions in the IS, bring the essay printed to the teacher who specified the topic and be ready to answer the teacher's questions regarding the topic.
In case of 3 absences, (or more than 3 absences all excused by the Office for Studies within 5 days from the beginning of the absence and introduced to the Information System), it is addressed individually and course-unit credit is awarded only after the proof of the student's knowledge of the entire semester topics (Credit test, see above).
In case of 4 or more unexcused absences, course-unit credit is not awarded.
Language of instruction
English
Follow-Up Courses
Further comments (probably available only in Czech)
The course is taught annually.
Information on the extent and intensity of the course: 30.
Listed among pre-requisites of other courses
Teacher's information
https://is.muni.cz/auth/el/1411/podzim2020/aZLBI0121c/index.qwarp
The course is also listed under the following terms Autumn 2015, Autumn 2016, Autumn 2017, autumn 2018, autumn 2019, autumn 2021.
  • Enrolment Statistics (autumn 2020, recent)
  • Permalink: https://is.muni.cz/course/med/autumn2020/aZLBI0121c