VSBI0222p Biology II - lecture

Faculty of Medicine
Spring 2009
Extent and Intensity
2/0/0. 4 credit(s). Recommended Type of Completion: zk (examination). Other types of completion: RZk (examination).
Teacher(s)
prof. Ing. Petr Dvořák, CSc. (lecturer)
doc. MVDr. Aleš Hampl, CSc. (lecturer)
prof. MUDr. Augustin Svoboda, CSc., dr. h.c. (lecturer)
prof. MUDr. Marie Kopecká, CSc. (lecturer)
doc. MUDr. Iva Slaninová, Ph.D. (lecturer)
prof. MUDr. David Šmajs, Ph.D. (lecturer)
Mgr. Stjepan Uldrijan, CSc. (lecturer)
Mgr. Hana Hříbková (assistant)
Mgr. Petra Pospíšilová, Ph.D. (assistant)
Debora Ledahudcová (assistant)
Ing. Lucia Ráheľová (assistant)
Eva Skalová (assistant)
Guaranteed by
prof. Ing. Petr Dvořák, CSc.
Department of Biology - Theoretical Departments - Faculty of Medicine
Timetable of Seminar Groups
VSBI0222p/01: Mon 11:30–12:20 N02901
VSBI0222p/02: Mon 10:30–11:20 N02901
Prerequisites (in Czech)
VSBI0121c Biology I-pract.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The course provides an overview of the current knowledge of molecular biology, genetics and human genetics in the context of other theoretical branches of the Faculty of Medicine. Recent and modern concepts of developmental biology, cell signaling, structural and epigenetic changes in the DNA, gene therapy and bioinformatics are discussed. In addition, an introduction to tumor biology is included. The subject matter presented in this course will help to better understand other subjects including physiology, pathology and human and clinical genetics.
Syllabus
  • Introduction to developmental biology. Molecular mechanisms of cell differentiation and death – relevance for cell pathologies. Basic principles and molecular mechanisms regulating early development of the mammals. Biology and use of stem cells. Growth factors and signal transduction. Introduction to cancer transformation. Structural DNA damage, epigenetic DNA modifications and repair mechanisms. Oncogenes and oncoviruses. Tumor supressor genes. Cancer stem cells. Gene therapy and biotherapeutics. Basics of bioinformatics. Milestones in biomedicine – some examples, Breakthrough of the year 2007 in molecular, cell or developmental biology with regard to biomedicine.
Literature
  • Snustad D. Peter, Simmons Michael D.: Principles of Genetics, 5th edition, Wiley&Sons, 2009.
  • Snustad D. Peter, Simmons Michael D.: Genetika (1.české vydání, přeloženo z Principles of Genetics), Nakladatelství Masarykovy univerzity 2009, 864 stran.
  • Campbell, N., A., Reece, J., B. 2006 Biologie. Computer press (ISBN: 80-251-1178-4)
  • Alberts, B., et al..: Základy buněčné biologie: úvod do molekulární biologie buňky. Espero Publishing, Ústí nad Labem 2005, 740, ISBN-10: 80-902906-2-0
  • Lodish, H., Berk, A., Matsudaira, P., Kaiser,C.A., Krieger, M., Scott, M.P., Zipurski, L., Darnell, J.: Molecular Cell Biology 5th ed., 2004 (ISBN: 0-7167-4366-3)
  • Pollard, Thomas D., Earnshaw, William C.: Cell Biology, 2nd ed., Saunders-Elsevier, Philadelphia, 2008
Assessment methods
Written test. The valid ICIS card is required to prove personal identity.
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course is taught annually.
Listed among pre-requisites of other courses

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Teacher's information
http://www.med.muni.cz/biologie/Edu-under.htm
The course is also listed under the following terms Spring 2000, Spring 2001, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2010, Spring 2011, Spring 2012, Spring 2013, Spring 2014, Spring 2015, Spring 2016.
  • Enrolment Statistics (Spring 2009, recent)
  • Permalink: https://is.muni.cz/course/med/spring2009/VSBI0222p