FAPC1_14 Human Physiology and Pathophysiology I

Farmaceutická fakulta
podzim 2021
2/1/0. 4 kr. Ukončení: z.
Vyučováno prezenčně.
MUDr. Marta Chalupová, Ph.D. (přednášející)
MUDr. Tomáš Parák, Ph.D. (přednášející)
MVDr. Jana Hložková, Ph.D. (cvičící)
MUDr. Marta Chalupová, Ph.D. (cvičící)
PharmDr. Mgr. Alžběta Kružicová (cvičící)
MUDr. Tomáš Parák, Ph.D. (cvičící)
PharmDr. Lenka Paráková, Ph.D. (cvičící)
MVDr. Peter Scheer, Ph.D. (cvičící)
MUDr. Tomáš Parák, Ph.D.
Ústav farmakologie a toxikologie - Ústavy - Farmaceutická fakulta
Út 8:00–9:40 seminární místnost, -037
  • Rozvrh seminárních/paralelních skupin:
FAPC1_14/01: každé sudé úterý 9:55–11:35 cvičebna, 140, T. Parák
Omezení zápisu do předmětu
Předmět je určen pouze studentům mateřských oborů.
Mateřské obory/plány
Cíle předmětu
Pathophysiology may be defined as the physiology of disease, or disordered function, or derangement of function seen in disease that is produced by the action of an etiologic agent (e.g. bacteria) on susceptible tissues or organs. The study of pathophysiology is an essential introduction to the use of drugs in clinical medicine and serves as a bridge between the basic sciences and the clinic.
Výstupy z učení
After completing the course, the student will be able to: - describe the physiology and pathophysiology of the main organs - recognize subjective and objective symptoms of diseases - examine the main physiological functions - interpret examination results
    1. Introduction into pathophysiology, symptoms of diseases and their diagnosing. Disease development. Genetic factors in pathogenesis.
    2. General physiological principles. Cell physiology. Function of cell membrane and intracellular structures. Basic principles of physiological regulation.
    3. Nonspecific defence mechanisms. Inflammation. Stress. Damage of organism (physical, chemical and biological)
    4. Specific defensive mechanisms and their disorders. Cell-mediated and antibody immunity. White blood cells, functions and disorders.
    5. Physiology of the locomotive apparatus. Most common diseases of bones, muscles and joints. Inflammatory and degenerative rheumatic diseases.
    6. Physiology of digestion and absorption, metabolism of sacharides, fats and proteins. Nutritional disorders ? obesity and starving. Metabolic syndrome.
    7. Vitamins, mineral substances and trace elements. Hyper and hypovitaminoses. Diseases of deficiency and excess of mineral substances and trace elements.
    8. Physiology of blood formation. Differential diagnosing of anaemia.
    9. Hemostasis and hemocoagulation. Coagulation cascade and its disorders. Hemorrhagic and hypercoagulable states.
    10. Physiology of the circulatory system. Formation and development of atherosclerosis. Ischemic heart disease.
    11. Formation and transmission of excitement and its disorders. Inherited and acquired heart disorders.
    12. Basic principles of the blood pressure regulation. Hypertensive disease. Hypotension. Circulation failure (shock).
    13. Theory of the formation of malignant growth. Tumours and their classification. Overview of clinically most common cancers.

    Syllabus of exercises:
    I. Main physiological functions and their watching
    1. Anamnesis, interview
    2. Objective and subjective anamnesis
    3. Basic checkup (examinations)
    II. Cardiovascular system
    1. Auscultation of heart sounds
    2. Measurement of blood pressure
    3. Electrocardiography
    III. Respiratory system
    1. Auscultation of lungs
    2. Spirometry, Pulse oxymetry
    3. Basal metabolism
    IV. Nervous system
    1. Hearing tests
    2. Eye tests
    3. Optical illusions
    4. EEG
    V. Urogenital tract, diabetes mellitus
    1. Semi-quantitative urinalysis
    2. Specific weight of urine
    3. Kidney functions
    4. Menstrual cycle, ovulation, gravidity
    VI. Blood, Good laboratory practice
    1. Red blood cells
    2. Blood count
    3. Haematocrit
    4. Erythrocyte sedimentation
    5. Differential leukocytes count
    VII. Obtaining credits
    povinná literatura
  • Stuart Ira Fox. Human Physiology. 2011. ISBN 978-0-07-337811-4. info
    doporučená literatura
  • COPSTEAD, BANASIK. Pathophysiology. 2005. ISBN 0-7216-0338-6. info
Výukové metody
Lectures, seminars, exercises, exercises in selected examination techniques, consultations
Metody hodnocení
To gain credits: Data analysis, seminar papers on given topics, written test. Completion of the course – oral exam
Vyučovací jazyk
Informace učitele
In accordance with study and examining order of credit system of the MUNI
Další komentáře
Studijní materiály
Předmět je dovoleno ukončit i mimo zkouškové období.
Předmět je zařazen také v obdobích podzim 2020, podzim 2022.