Bi7070 Physiology of Cell Systems

Faculty of Science
Autumn 2016
Extent and Intensity
2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
prof. RNDr. Alois Kozubík, CSc. (lecturer)
prof. RNDr. Jiřina Hofmanová, CSc. (lecturer)
prof. RNDr. Jan Vondráček, Ph.D. (lecturer)
Mgr. Karel Souček, Ph.D. (lecturer)
doc. RNDr. Alena Hyršlová Vaculová, Ph.D. (lecturer)
Guaranteed by
prof. RNDr. Alois Kozubík, CSc.
Department of Experimental Biology - Biology Section - Faculty of Science
Contact Person: prof. RNDr. Alois Kozubík, CSc.
Supplier department: Department of Experimental Biology - Biology Section - Faculty of Science
Mon 19. 9. to Sun 18. 12. Tue 12:00–13:50 BFU
Basic knowledge of biochemistry, cell and molecular biology are neccessary
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
there are 7 fields of study the course is directly associated with, display
Course objectives
At the end of the course students should be able to: understand cell functions, development and control of cytokinetics (proliferation, differentiation and apoptosis), and the mechanisms of action of hormones, cytokines and other regulatory molecules; use acquired knowledge of the processes taking place at the level of plasmatic membrane, cytosol and nucleus, i.e. signal transduction at the molecular level; explain the feedback mechanisms and the outcomes of disruptions of cellular regulation in the whole organism - reactions such as stress, inflammation, and carcinogenesis; orientate in mutual relationships on various regulation levels of mammalian organism (from molecules to the whole system).
  • 1. Introduction to theory of the systems 2. Cell population types 3. Regulation of cytokinetics Cell cycle and its regulation Growth stimulators and inhibitors 4. Structure and function of cell membranes Lipid mediators and cytokines Signal transduction and expression of genetic information Hematopoietic system and its functions Membrane recognition and immune systems 6. Homeostasis, health and disease Organism as hierarchic system Cooperation of nervous, endocrine and humoral systems 7. Harmful environmental factors and human health risk
    required literature
  • ALBERTS, Bruce. Základy buněčné biologie : úvod do molekulární biologie buňky. Translated by Arnošt Kotyk. 2. vyd. Ústí nad Labem: Espero Publishing, 2004. xxvi, 630. ISBN 8090290620. info
  • VOET, Donald and Judith G. VOET. Biochemie. Translated by Arnošt Kotyk. 1. vyd. Praha: Victoria Publishing, 1995. S. II-XIV,. ISBN 80-85605-44-9. info
    recommended literature
  • ALBERTS, Bruce. Molecular biology of the cell. 3rd ed. New York: Garland Publishing, Inc., 1994. xliii, 129. ISBN 0-8153-1620-8. info
  • Cell Physiology Source Book, ed. N. Sperelakis, Academic Press Inc., 1995
  • TROJAN, Stanislav. Lékařská fyziologie. 3. dopl. a přeprac. vyd. Praha: Grada, 1999. 612 s. ISBN 8071697885. info
  • The cytokine handbook, ed. A. W. Thompson, Academic Press New York, 1994
  • Functional metabolism, Regulation and Adaptation, ed. K. B. Storey, Wiley-Liss, Inc., Hoboken, New Jersey, 2004
  • Handbook of cell signaling, Vol. 1, 2, 3, eds. R. A. Bradshaw, E. A. Dennis, Academic Press, Elsevier Science 2004
  • ŠTERZL, Jaroslav. Imunitní systém a jeho fyziologické funkce. Praha: Česká imunologická společnost, 1993. 480 s. info
  • KOTYK, Arnošt. Struktura a funkce biomembrán. 1. vyd. Brno: Masarykova univerzita, 1996. 173 s. ISBN 8021013168. info
  • Doporučené speciální separáty a elektronické prezentace přednášek. (Recommended thematic research papers and electronic presentation of the lectures)
Teaching methods
Lectures and class discussion. Students are asked questions dealing with subject of the past lectures.
Assessment methods
Attendance of the lectures is not mandatory but highly recommended for right understanding of educated topics. During lectures students are asked about subjects of past lectures. The course is finished by written exam evaluated by the teacher. Questions go through all teaching topics. Students must answer about 20 questions which go through all topics discoursed. 60% of correct answers is needed to pass.
Language of instruction
Follow-Up Courses
Further comments (probably available only in Czech)
Study Materials
The course can also be completed outside the examination period.
The course is taught annually.
Information on course enrolment limitations: Na předmět se vztahuje povinnost registrace, bez registrace může být znemožněn zápis předmětu!
Listed among pre-requisites of other courses
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2002, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, autumn 2017, Autumn 2018, Autumn 2019, Autumn 2020.
  • Enrolment Statistics (Autumn 2016, recent)
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