C7440 Coordination and Catalysis

Faculty of Science
Autumn 2015
Extent and Intensity
1/0/0. 2 credit(s) (fasci plus compl plus > 4). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium).
Teacher(s)
doc. RNDr. Pavel Pazdera, CSc. (lecturer)
Guaranteed by
doc. RNDr. Pavel Pazdera, CSc.
Department of Chemistry - Chemistry Section - Faculty of Science
Supplier department: Department of Chemistry - Chemistry Section - Faculty of Science
Prerequisites
C2021 Organic Chemistry I && C3022 Organic Chemistry II/1 || C2700 Basic Organic Chemistry
The knowledge of the generall, inorganic and organic chemistry, organic synthesis.
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
there are 8 fields of study the course is directly associated with, display
Course objectives
At the end of the course students should be able to understand and explain principles and applications of transition metals and their complexes in synthesis. Knowledge of different ways of chemical activation and study methods of the reaction mechanisms will help the student to understand the scientific literature in the corresponding field and interpret the results from the experimental and theoretical studies.
Syllabus
  • Molecular orbitals of transition metal complexes (ability for bonding, ligand characters, pi-donor, pi-acceptor, d-pi-akceptor ligands), Active particles and catalytic cycles (variability of oxidative states and coordination number, rule of 16/18 electrons). Formation of active particles-activation of substrates by coordination, by addition (oxidative, homolytic and heterolytic addition), elemental processes of coordinated ligands-migration and insertion, migration of coordinated ligands and other reactions, alpha-, beta-eliminations, reductive eliminations and other reactions terminate catalytic cycle).
  • Formation of single and double C-C bonds, coupling reactions (dimerization of alkenes, cross coupling, alkyne syntheses, alkylation by palladium and similar catalyst complexes). Syntheses with application of sigma- and pi-arene complexes (character of coordination and reactivity of coordinated substrates), metathesis of alkenes, allenes.
  • Synthesis of carbocycles. Heterocycles synthesis.
  • Alkenes isomerization.
  • Direct insertion of carbonyl.
  • Redox reactions, hydrogenation and reduction of multiple bond C-C, C-N, C-O, C-S, N-O, asymmetric hydrogenation,hydrogenolysis, alkene oxidation, epoxidation, dehydrogenation etc. Stereochemistry of syntheses, chirality of catalysts.
Literature
  • Nakamura, A.; Tsutsui, M. Principles and Applications of Homogeneous Catalysis, J. Wiley New York 1980
  • Colquhoun, H. M.; Holton, J.; Thompson, D. J.; Twigg, M. V. New Pathways for Organic Synthesis, Plenum Press, New York 1981,400 str., ISBN 5-7245-0357-3
  • Masters, Ch. Homogeneous Transition-Metal Catalysis, Chapman and Hall, New York 1981
  • Petrovič, P.; Haber, V.; Toma, Š. Základy koordinačnej chémie, Univerzita Komenského Bratislava 1983
Teaching methods
Lectures.
Assessment methods
One written final test (51% of correct answers is needed to pass) and the oral exam.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
The course is taught annually.
The course is taught: every week.
General note: Znalost předmětu bude vyžadována u magisterské státní závěrečné zkoušky!.
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 1999, Autumn 2010 - only for the accreditation, Autumn 2000, Autumn 2001, Autumn 2002, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2019.
  • Enrolment Statistics (Autumn 2015, recent)
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