PřF:C6210 Biotechnology - Course Information
C6210 BiotechnologyFaculty of Science
- Extent and Intensity
- 2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
- doc. Ing. Martin Mandl, CSc. (lecturer)
- doc. Ing. Martin Mandl, CSc.
Department of Biochemistry - Chemistry Section - Faculty of Science
Contact Person: doc. Ing. Martin Mandl, CSc.
Supplier department: Department of Biochemistry - Chemistry Section - Faculty of Science
- Thu 9:00–10:50 A11/205
- ( Bi1700 Cell Biology || C7920 Struct. and func. of proteins || CG010 Proteomics || C1470 Introduction to mathematics for chemoinformatics and bioinformatics || SOUHLAS ) && ! NOWANY ( C6211 Biotechnology )
Basic knowledge of biochemistry and cell biology.
- Course Enrolment Limitations
- The course is offered to students of any study field.
- Course objectives
- The goals are biochemical principles of traditional and recent biotechnologies and fundamental processes in fermenters and other apparatuses which provide the biotechnological use of metabolic activity of organisms or enzymes.
- Learning outcomes
- Students will be able:
-to be knowledgeable about biochemistry and physiology of organisms in relation to their use in biotechnology;
-to know principles of selected fermentation processes and application of biotechnology to environmental protection;
-to understand basic biotechnological operations and processes taking part in bioreactors of various construction;
-to understand fundamental knowledge of microbial kinetics.
- Microbial and enzyme biotechnology, historical survey. Biochemistry, microbiology and engineering principles.
- Biochemical and chemical principles of classical and recent biotechnologies. Beer, wine and organic acid production.
- Microbial biomass production as a protein supply, biomining, biomedicine).
- Environmental biotechnology. Bioremediation (heavy metals, hydrocarbons), biogas, biofuels, algae biotechnology, bioelectricity).
- Cultivation and production bioreactors, scale-up. Agitation in fermenters, the impact on metabolic activity of organisms.
- Aeration in bioprocesses. Oxygen transfer.
- Determination of the mass-transfer oxygen coefficient. Aeration parameters in bioreactors in relation to oxygen demand by production cultures and enzymes, scale-up.
- Batch culture. Growth and production kinetics. Models of substrate utilization and product formation.
- Cell growth and death kinetics. Kinetic models in biotechnology and microbial (cell) physiology, the model selection.
- Continuous culture. Determination of kinetic and physiological parameters in a chemostat. The relationship with the batch culture.
- Immobilised cells and enzymes, principles and applications.
- Bioreactors based on immobilised cells and enzymes.
- recommended literature
- KAŠTÁNEK, František. Bioinženýrství. Vyd. 1. Praha: Academia, 2001. 334 s. ISBN 8020007687. info
- STANBURY, Peter F., Allan WHITAKER and Stephen J. HALL. Principles of fermentation technology. 2nd ed. Oxford: Pergamon, 1995. xviii, 357. ISBN 0-08-036131-5. info
- DORAN, Pauline M. Bioprocess engineering principles. London: Academic Press, 1995. xiv, 439 s. ISBN 0-12-220856-0. info
- KRUMPHANZL, Vladimír and Zdeněk ŘEHÁČEK. Mikrobiální technologie : buňka a techniky jejího využití. 1. vyd. Praha: Academia, 1988. 360 s., 24. info
- ALEXANDER, Martin. Biodegradation and bioremediation. San Diego: Academic Press, 1994. 302 s. ISBN 0-12-049860-X. info
- Teaching methods
- Lectures on selected parts of biotechnology. Discussions on detailed subjects.
- Assessment methods
- Lectures, discussions during lectures. Oral exam. Understanding of principles and processes is required. Fifty % of correct answers from the part of bioprocess kinetics is required to continue with the exam.
- Language of instruction
- Further comments (probably available only in Czech)
- Study Materials
The course can also be completed outside the examination period.
The course is taught annually.
- Listed among pre-requisites of other courses