PřF:C2022 Organic Chemistry I - Seminar - Course Information
C2022 Organic Chemistry I - SeminarFaculty of Science
- Extent and Intensity
- 0/2/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: z (credit).
- doc. Mgr. Kamil Paruch, Ph.D. (lecturer)
Mgr. Jakub Švenda, PhD. (lecturer)
RNDr. Slávka Janků, Ph.D. (seminar tutor)
Mgr. Jaromír Literák, Ph.D. (seminar tutor)
- Guaranteed by
- RNDr. Slávka Janků, Ph.D.
Department of Chemistry - Chemistry Section - Faculty of Science
Supplier department: Department of Chemistry - Chemistry Section - Faculty of Science
- Timetable of Seminar Groups
- C2022/01: Thu 16:00–17:50 A08/309, J. Literák
C2022/02: Tue 14:00–15:50 A08/309, S. Janků
C2022/03: Thu 11:00–12:50 A08/309, S. Janků
C2022/04: Thu 9:00–10:50 A08/309, J. Literák
C2022/05: Mon 17:00–18:50 A08/309, J. Literák
C2022/06: Fri 8:00–9:50 C12/311, S. Janků
- NOW ( C2021 Organic Chemistry I )|| C2021 Organic Chemistry I
Knowledge of general and inorganic chemistry.
- Course Enrolment Limitations
- The course is also offered to the students of the fields other than those the course is directly associated with.
- fields of study / plans the course is directly associated with
- Analytical Chemistry (programme PřF, N-CH)
- Analytical Chemist - Manager of Chemical Laboratory (programme PřF, B-CH)
- Inorganic Chemistry (programme PřF, N-CH)
- Applied Biochemistry (programme PřF, B-AB)
- Biochemistry (programme PřF, B-BCH)
- Physical Chemistry (programme PřF, N-CH)
- Chemistry of Conservation - Restoration (programme PřF, B-CH)
- Chemistry (programme PřF, B-CH)
- Chemistry with a view to Education (programme PřF, B-GE)
- Chemistry with a view to Education (programme PřF, B-GK)
- Chemistry with a view to Education (programme PřF, B-CH)
- Chemistry with a view to Education (programme PřF, B-MA)
- Environmental Chemistry (programme PřF, N-CH)
- Molecular Biology and Genetics (programme PřF, B-EXB)
- Organic Chemistry (programme PřF, N-CH)
- Course objectives
- The aim of this special seminar course is to exercise the topics introduced in lecture Organic Chemistry I on practical examples. The topics involve basic drafts such as principles of chemical nomenclature, principles of stereochemistry, major study methods of the structure of organic compounds, theories of acidity and basicity. Students will be introduced to the major types of organic chemistry reactions such as ionic, radical, redox and some orbital steering reactions.
- Learning outcomes
- The Organic Chemistry I course graduates will be able to understand basic drafts of organic chemistry such as acidity and basicity, equilibrium of chemical reactions etc.;
They will be able to understand and describe mechanism of basic types of organic chemistry reactions;
On the bases of the gained knowledge they will be able to explain differences in reactivity between individual groups of organic compounds;
They will have created necessary foundation for graduating the followed course Organic Chemistry II, where they use obtained knowledge for planning complicated organic compounds syntheses.
- 1. The scope of Organic Chemistry. Drawing organic molecules. Basic principles of nomenclature. Aliphatic and cyclic skeletons, hierarchy of functional groups. 2. Carbon atom bonding. Hybridization of atomic orbitals, bond angles. Electron structure of molecules, sigma and pi-bond. Molecular orbitals, conjugation and delocalization. Mesomeric effect and resonance structures. Polarity and polarizability, charge distribution in molecules. 3. Basics of organic stereochemistry. Drawing organic molecules. Isomers and stereoisomers. Conformation and configuration. Geometric isomerism of alkenes and cycloalkanes. Conformation of ethane, butane and cyclohexane. Symmetry and chirality. Cahn-Ingold-Prelog nomenclature. Fischer projection. 4. Organic structures determination methods (MS,NMR, IR, UV-Vis). 5. Chemical reactions. Homolysis and heterolysis. Classification of organic reactions according to structural change (S-A-E-R). Reaction mechanism - "Arrow pushing". Depiction of organic reaction. Kinetics and thermodynamics. 6. Acids and Bases. Broensted theory. Chemical equilibrium. pH, pKa. Strength of (organic) acids and bases. Electrophiles and nucleophiles. Lewis theory. Hard and Soft Acids and Bases (HSAB). 7. Oxidation reduction reactions.SN1 and SN2 mechanisms 8. Nucleophilic subtitution and elimination reactions (halogen derivatives, alcohols, amines). Reaction kinetics, rate determining reaction step, carbocations stability, reaction stereospecifity. 9. Nucleophilic addition on cabonyl group. Michael addition, keto-enol tautomerism, Adition-elimination mechanism. 10. Electrophilic addition reactions. Alkenes, alkynes. Radical addition and polymerization. Radical substitution. 1,2- and 1,4-addition reactions pf conjugated dienes. 11. Aromaticity. Electrophilic aromatic substitution. Nucleophilic substituon. 12. Reaction with conservation of orbytal symmetry. Pericyclic reactions. Diels-Alder rection.
- Potáček, Milan - Mazal, Ctibor - Janků, Slávka. Řešené příklady z organické chemie. 1. vyd. Brno : Masarykova univerzita v Brně, 2005. 243 s. ISBN 80-210-2274-4. info
- POTÁČEK, Milan and Eduard NOVÁČEK. Organická chemie : příručka řešených příkladů. Edited by Slávka Janků. 1. vyd. Brno: Masarykova univerzita, 1997. 201 s. ISBN 8021016728. info
- MCMURRY, John. Organická chemie. Translated by Jaroslav Jonas. Vyd. 1. Praha: Vysoká škola chemicko-technologická v Praze, 2007. 1 sv. ISBN 9788070806371. info
- LITERÁK, Jaromír. Sbírka řešených příkladů k semináři z organické chemie (Collection of Excercises in Organic Chemistry). 1. vydání. Brno: Masarykova univerzita, 2012. 308 pp. ISBN 978-80-210-5810-1. info
- Teaching methods
- class discussions upon the corresponding lecture topics
- Assessment methods
- During the course several tests are written and their good results are the conditions for credits obtaining.
- Language of instruction
- Further comments (probably available only in Czech)
- Study Materials
The course is taught annually.