PřF:IC037 Bio-Organic Chemistry - Course Information
IC037 Bio-Organic ChemistryFaculty of Science
- Extent and Intensity
- 1/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
- Prof. Dr. Romano Orru (lecturer), prof. RNDr. Milan Potáček, CSc. (deputy)
- Guaranteed by
- prof. RNDr. Milan Potáček, CSc.
Department of Chemistry - Chemistry Section - Faculty of Science
- C3022 Organic Chemistry II
Basic knowledge of Organic Chemistry
- Course Enrolment Limitations
- The course is offered to students of any study field.
- Course objectives
- After following the course, students should be able to: - Recognize and interconvert different forms of representation of natural products (e.g. carbohydrates); - Classify and analyze natural products according to their biosynthetic origin and describe the reactions involved in their biosynthesis; - Explain the most important mechanisms of major biosynthetic pathways; - Provide plausible mechanisms for conversions in natural product biosynthesis based on studied textbook examples;; - Explain what type of organism produces a specific compound based on the type of secondary metabolism involved in the biosynthesis; - Describe major cellular events and functions (and their place in the cell cycle) that can be perturbed by natural products; - Analyze structural modifications to biologically active natural products to give (semi)synthetic derivatives and explain how they may contribute to better pharmaceutical properties; - Understand the principles that determine the specificity and activity of enzymes and the mechanisms of some enzyme reactions on a molecular scale;
- General The course Bio-Organic Chemistry consists The topic Natural Products, which gives a detailed overview of the fundamental classes of natural products. Not only the basic structural and physical properties, but also synthetic aspects and biosynthesis are a major part of this course. Furthermore, the role of natural products in biological studies and pharmaceutical development will be discussed.
- Medicinal Natural Products – A Biosynthetic Approach”, 2nd edition, Paul M. Dewick, John Wiley & Sons, 2001, ISBN 13 978 0 471 49641 0
- Teaching methods
- Lectures with discussions
- Language of instruction
- Further comments (probably available only in Czech)
- Study Materials
The course is taught only once.
The course is taught: in blocks.
Note related to how often the course is taught: 8.-10.12.2009.