Bi9533 Intracellular signalling in development and disease

Faculty of Science
Autumn 2009
Extent and Intensity
2/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: z (credit).
prof. Mgr. Vítězslav Bryja, Ph.D. (lecturer)
Guaranteed by
prof. RNDr. Alois Kozubík, CSc.
Department of Experimental Biology - Biology Section - Faculty of Science
Contact Person: prof. Mgr. Vítězslav Bryja, Ph.D.
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aim of this subject is to introduce students of Biology and Biomedicine to the most recent advances in the field of intracellular communication. The series of talks will be given by top Czech and mainly foreign specialists. The lectures are combined in a way, which will provide as broad as possible overview of methods and models used to study intracellular signaling. The subject is primarily aimed for PhD students but is also available for others. The subject will be taught in English.
  • 1. Zbyněk Kozmík (Institute of Molecular Genetics, AS CR, Prague): Intracellular signalling in the eye development
  • 2. Vítězslav Bryja (Faculty of Science, Masaryk University, Brno): Wnt signalling at the membrane and in the cytoplasm
  • 3. Vladimír Kořínek (Institute of Molecular Genetics, AS CR, Prague): Nuclear Wnt signalling
  • 4. Tomas Doležal (University of South Bohemia, České Budějovice): dco/CKIepsilon and Drosophila model for breast cancer
  • 5. Gunnar Schulte(Karolinska Institutet, Stockholm): Frizzled receptors.
  • 6. Pascale Zimmerman (Catholic University, Leuven): PDZ motif containing proteins in Wnt signaling.
  • 7. Carsten Janke (CNRS, Montpellier): Post-translation modification of tubulin and its functions.
  • 8. Masako Asahina(Biology Centre AS CR, České Budějovice): C. elegans as a model for study of intracellular signalling
  • 9. Marek Jindra (University of South Bohemia, České Budějovice): Steroids and other lipophilic derivatives in the development of insects
  • 10. Alexandra Schambony (University of Erlangen, Germany): Non-canonical Wnt signaling in Xenopus
  • 11. Madelone Maurice (University of Utrecht, Netherlands): Ubiquitination in the Wnt pathway
  • 12. Gustavo Miranda-Carboni (University of California Los Angeles, USA): Link between Wnt signalling and cell cycle regulation in the mammary cancer.
Teaching methods
The series of lectures.
Assessment methods
Students are required to attend the lectures.
Language of instruction
Further comments (probably available only in Czech)
Study Materials
The course is taught only once.
The course is taught: every week.
Information on course enrolment limitations: Předmět je primárně určen pro studenty magisterských a doktorských studijních programů.

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