PřF:Bi9325 Human molecular genetics - Course Information
Bi9325 Human molecular geneticsFaculty of Science
- Extent and Intensity
- 2/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
- Ferák (lecturer), prof. RNDr. Jiří Doškař, CSc. (deputy)
RNDr. Vladimíra Vallová, Ph.D. (lecturer)
přednášející z LF MU (lecturer)
- Guaranteed by
- prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology - Biology Section - Faculty of Science
Contact Person: RNDr. Vladimíra Vallová, Ph.D.
- Tue 15:00–16:50 BR2
- Prerequisites (in Czech)
- ( B7250 Human genetics || Bi7250 Human genetics ) && ( Bi6081 Bakalářská státní závěrečná zkouška z Molekulární biologie a genetiky || Bi6082 Bakalářská státní závěrečná zkouška z Obecné biologie || Bi6087 Bakalářská státní závěrečná zkouška z Buněčné a molekulární diagnostiky || SOUHLAS )
- Course Enrolment Limitations
- The course is also offered to the students of the fields other than those the course is directly associated with.
- fields of study / plans the course is directly associated with
- Course objectives
- The aim of this course is to provide students a molecular-genetic insight into selected areas of human genetics. At the end of this course, students should be able to describe the structure of the human genome and apply the principles of methods used in its analysis. They should also understand the Human Genome Project (HGP) and interpret the use of information gained under HGP framework. They should also compose molecular aspects of human evolution and understand molecular principles of genetic diseases in human (monogenic and polygenic), as well as formulate the priciples of human pharmacogenetics, gene therapy and forenzic genetics.
- Structure and expresion of human genome. Multigene families and repetitive DNA. Polymorphism in human DNA; detection and screening of mutation in human genome. Gene identification and isolation methods. Molecular aspects of human evolution. Human Genome Project, history and principles of human genome mapping. Somatic mutations and cancer. Molecular pathology. Complex diseases. Pharmacogenetics. Gene therapy. Forensic genetics.
- Human molecular genetics. Edited by Tom Strachan - Andrew P. Read. 1st ed. Oxford: BIOS Scientific Publishers, 1997. xiv, 597 s. ISBN 1-872748-69-4. info
- Teaching methods
- Presentations by experts in the sectors. The Powerpoint presentations are used.
- Assessment methods
- Written test. Student selects one or more possibility from 4 answers. To pass the exam, 60% of the points is required.
- Language of instruction