Study plan
PřF GEPRA Genomics and Proteomics
Name in Czech: Genomics and Proteomics
doctoral full-time, language of instruction: English![English English](/pics/flags_svg/gb.svg)
Included in the programme: PřF D-GEPRA_ Genomics and Proteomics
doctoral full-time, language of instruction: English
Included in the programme: PřF D-GEPRA_ Genomics and Proteomics
Study-related information
- Final state doctoral examination and defence of the doctoral thesisStudent must pass the Final State Exam, which is to prove student's professional orientation in the field of genomics and proteomics and other related disciplines, particularly in molecular and cellular biology, structural biology, bioinformatics, and in the experimental approaches used in the field. The exam topics are selected by supervisor in advance. The student should especially be able to prove sufficient general knowledge in the field studied and in-depth knowledge in areas related to his/her Ph.D. thesis, including being familiar with recent major publications in their field of expertise.
Before the dissertation thesis defence can take place, student must publish first-author paper (or the manuscript must be accepted for publication) in impacted international journal indexed in Web of Science (WoS) with impact factor above the subject median (or two publications must be published if the IF is below the median).
The dissertation thesis defence starts with presentation of major scientific achievements and is followed by discussions with referees and committee members. Student must prove her/his ability to work and develop research independently, to present and defend her/his results and conclusions. - Requirements of the studyResearch activities:
Dissertation thesis preparation – runs throughout the whole studies (at least 60% of the workload)
Read relevant literature
Publication activity – student must publish first-author paper in impacted international journal indexed in Web of Science (WoS) with impact factor above the subject median, 10% of the workload
Dissertation thesis defence
Active participation at an international conference
Internship abroad - student must spend 1 month in a lab abroad (can be cumulated)
Education activities:
Special subjects - to complement and extend the student's topic (defined in Study plan section - 20% of the workload at most)
Mandatory Genomics and Proteomics seminar
Teaching activity – student can participate in supervision of bachelor and master students, and in regular teaching activities (not more than 150 hours - 10% of the workload at most)
Soft skills - e.g. Academic writing,
Scientific English - Proposal of dissertation topics and topics of defended dissertationsExamples of (10 selected) successfully defended dissertations:
Veronika Pavlištová: Effect of chromatin assembly on genome stability (https://is.muni.cz/auth/th/wx0ba/)
Kateřina Zábrady: Analysis of MAGE (Melanoma AntiGEn) proteins and their interaction partners (https://is.muni.cz/auth/th/ap968/)
Eliška Janoušková: Dynamics of Telomeric Proteins (https://is.muni.cz/auth/th/pm7q7/)
Kateřina Šedová: Characterisation of Protein Modifications by Mass Spectrometry (https://is.muni.cz/auth/th/eypvg/)
Zuzana Vrzalová: Complex molecular diagnostics of congenital adrenal hyperplasia (https://is.muni.cz/auth/th/x4k2c/)
Karin Jaške: Crossroads of genetics and epigenetics: nucleosome assembly and chromosome integrity (https://is.muni.cz/auth/th/laaa5/)
Markéta Žďárská: Differential proteomics and phosphoproteomics of hormonal regulations in plants (https://is.muni.cz/auth/th/dhio8/)
Michal Zimmermann: Protein-DNA interactions involved in regulation of telomere maintenance (https://is.muni.cz/auth/th/fsxl1/)
Marc Guerineau: Analysis of SMC5-6 complex subunits and their functional homologs (https://is.muni.cz/auth/th/uccar/)
Eva Majerová: Epigenetic mechanisms in the regulation of telomere maintenance (https://is.muni.cz/auth/th/eyt2h/)
Recommended progress through the study plan
Required
Student works on the thesis throughout the studies. Student must publish first-author paper. During studies, student must present her/his results at seminars and conferences. She/he should learn how to transfer knowledge to new generations (by participating in teaching).
Code | Name | Type of Completion | Credits | Term | Profile Cat. |
PřF:C9950 | Seminar of the Dept. Functional Genomics and Proteomics | z | 2 | - | - |
2 credits |
Selective
Student subscribes those subjects which prepare him for the Final state exam in Genomics and proteomics. She/he shall choose subjects best fitting to students curriculum to become real specialist.
Code | Name | Type of Completion | Credits | Term | Profile Cat. |
PřF:CG020 | Genomics | zk | 2+2 | - | - |
PřF:C2131 | Introduction to bioinformatics | zk | 2+2 | - | - |
PřF:C2132 | Introduction to bioinformatics - seminar | z | 1 | - | - |
PřF:C2135 | Bioinformatics for practice | k | 2+1 | - | - |
PřF:C2138 | Advanced bioinformatics | zk | 2+2 | - | - |
PřF:C2139 | Advanced bioinformatics - seminary | z | 1 | - | - |
PřF:C7301 | Genomics - practice | k | 3 | - | - |
PřF:C9025 | Evolutionary and comparative plant genomics | zk | 2+2 | - | - |
PřF:C9035 | Evolutionary and comparative plant cytogenetics - practice | k | 2 | - | - |
PřF:C9041 | Structure and function of eukaryotic chromosomes | zk | 2+2 | - | - |
PřF:C9042 | Analysis of chromatin structure - practical training | z | 2 | - | - |
PřF:C8202 | Proteomics - a basic course | zk | 1+2 | - | - |
PřF:C8302 | Proteomics - practice | k | 3 | - | - |
PřF:C9530 | Structure of biomacromolecules | zk | 2+2 | - | - |
PřF:C9531 | Structure of biomacromolecules | z | 2 | - | - |
PřF:CG010 | Proteomics | zk | 2+2 | - | - |
PřF:CG030 | Structure and function of protein complexes | zk | 2+2 | - | - |
PřF:CG080 | Methods in genomics | zk | 2+2 | - | - |
PřF:CG090 | Methods in proteomics | zk | 2+2 | - | - |
PřF:CG031 | Practical course in modelling of complexes | z | 2 | - | - |
PřF:C7250 | Protein characterisation using mass spectrometry | k | 1+1 | - | - |
PřF:C7350 | Protein characterisation using mass spectrometry - practice | z | 1 | - | - |
65 credits |
Elective
Following subjects wider their offer to cultivate student's soft skills, English competences and in-depth knowledge.
Code | Name | Type of Completion | Credits | Term | Profile Cat. |
PřF:Bi8350 | Evolutionary genomics | zk | 2+2 | - | - |
PřF:C3900 | Molecular mechanisms of cell aging | zk | 1+2 | - | - |
PřF:C6210 | Biotechnology | zk | 2+2 | - | - |
PřF:C7072 | Bioanalytics II - Analytical methods in clinical praxis | zk | 2+2 | - | - |
PřF:C7073 | Bioanalytics I - Biomacromolecules | zk | 2+2 | - | - |
PřF:C7230 | Fluorescence methods in life sciences - a journey from molecules to cells | zk | 2+2 | - | - |
PřF:C7235 | Fluorescence methods in life sciences - excercise | k | 2+1 | - | - |
PřF:C7250 | Protein characterisation using mass spectrometry | k | 1+1 | - | - |
PřF:C7490 | Molecular diagnostics of inherited diseases | zk | 1+2 | - | - |
PřF:C8857 | Protein Preparation and Characterization III - Protein-mediated interactions | zk | 1+2 | - | - |
PřF:C8980 | Protein Preparation and Characterization I - Expression and Purification | zk | 2+2 | - | - |
PřF:C9045 | Biology of yeasts | zk | 2+2 | - | - |
PřF:C9085 | Protein-RNA interactions | zk | 1+2 | - | - |
PřF:C9142 | Biology of yeasts - practice | z | 2 | - | - |
PřF:C9285 | Praxis of science and research - publication and projects | k | 2 | - | - |
PřF:F8310 | The molecular interactions in biology and chemistry | k | 3+1 | - | - |
PřF:JA003 | English for Science - Elective Course | k | 3 | - | - |
PřF:S1001 | Chemical properties, structure and interactions of nucleic acids | zk | 3+2 | - | - |
PřF:S2008 | Developmental and cellular biology of plants | zk | 4+2 | - | - |
PřF:S2011 | Hormones in plant development | zk | 2+2 | - | - |
PřF:S4001 | International performance | zk | 2+2 | - | - |
PřF:S4002 | Law, ethics and philosophy of science | k | 2+2 | - | - |
PřF:S2009 | Mendel Centre Seminars in the Bio-omics | z | 2 | - | - |
PřF:S5020 | Life Science PI Seminars | z | - | - | - |
PřF:XD010 | Masaryk University Life Sciences Seminar sponsored by CEITEC and ICRC | z | 2 | - | - |
83 credits |