Studijní plán

Student must pass the Final State Exam, which is to prove student's professional orientation in the field of genomics and proteomics and other related disciplines, particularly in molecular and cellular biology, structural biology, bioinformatics, and in the experimental approaches used in the field. The exam topics are selected by supervisor in advance. The student should especially be able to prove sufficient general knowledge in the field studied and in-depth knowledge in areas related to his/her Ph.D. thesis, including being familiar with recent major publications in their field of expertise.

Before the dissertation thesis defence can take place, student must publish first-author paper (or the manuscript must be accepted for publication) in impacted international journal indexed in Web of Science (WoS) with impact factor above the subject median (or two publications must be published if the IF is below the median).

The dissertation thesis defence starts with presentation of major scientific achievements and is followed by discussions with referees and committee members. Student must prove her/his ability to work and develop research independently, to present and defend her/his results and conclusions.

Research activities:
Dissertation thesis preparation – runs throughout the whole studies (at least 60% of the workload)
Read relevant literature
Publication activity – student must publish first-author paper in impacted international journal indexed in Web of Science (WoS) with impact factor above the subject median, 10% of the workload
Dissertation thesis defence
Active participation at an international conference
Internship abroad - student must spend 1 month in a lab abroad (can be cumulated)

Education activities:
Special subjects - to complement and extend the student's topic (defined in Study plan section - 20% of the workload at most)
Mandatory Genomics and Proteomics seminar
Teaching activity – student can participate in supervision of bachelor and master students, and in regular teaching activities (not more than 150 hours - 10% of the workload at most)
Soft skills - e.g. Academic writing,
Scientific English

Examples of (10 selected) successfully defended dissertations:

Veronika Pavlištová: Effect of chromatin assembly on genome stability (https://is.muni.cz/auth/th/wx0ba/)

Kateřina Zábrady: Analysis of MAGE (Melanoma AntiGEn) proteins and their interaction partners (https://is.muni.cz/auth/th/ap968/)

Eliška Janoušková: Dynamics of Telomeric Proteins (https://is.muni.cz/auth/th/pm7q7/)

Kateřina Šedová: Characterisation of Protein Modifications by Mass Spectrometry (https://is.muni.cz/auth/th/eypvg/)

Zuzana Vrzalová: Complex molecular diagnostics of congenital adrenal hyperplasia (https://is.muni.cz/auth/th/x4k2c/)

Karin Jaške: Crossroads of genetics and epigenetics: nucleosome assembly and chromosome integrity (https://is.muni.cz/auth/th/laaa5/)

Markéta Žďárská: Differential proteomics and phosphoproteomics of hormonal regulations in plants (https://is.muni.cz/auth/th/dhio8/)

Michal Zimmermann: Protein-DNA interactions involved in regulation of telomere maintenance (https://is.muni.cz/auth/th/fsxl1/)

Marc Guerineau: Analysis of SMC5-6 complex subunits and their functional homologs (https://is.muni.cz/auth/th/uccar/)

Eva Majerová: Epigenetic mechanisms in the regulation of telomere maintenance (https://is.muni.cz/auth/th/eyt2h/)