| ALTMANNOVÁ, Veronika, Peter KOLESÁR a Lumír KREJČÍ. SUMO Wrestles with Recombination. Online. Biomolecules. Basel, Switzerland: MDPI AG, 2012, roč. 2, č. 3, s. 350-375. ISSN 2218-273X. Dostupné z: https://dx.doi.org/10.3390/biom2030350. [citováno 2024-04-24] |
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@article{1066875,
author = {Altmannová, Veronika and Kolesár, Peter and Krejčí, Lumír},
article_location = {Basel, Switzerland},
article_number = {3},
doi = {http://dx.doi.org/10.3390/biom2030350},
keywords = {SUMO homologous recombination},
language = {eng},
issn = {2218-273X},
journal = {Biomolecules},
title = {SUMO Wrestles with Recombination},
url = {http://www.mdpi.com/2218-273X/2/3/350},
volume = {2},
year = {2012}
}
TY - JOUR
ID - 1066875
AU - Altmannová, Veronika - Kolesár, Peter - Krejčí, Lumír
PY - 2012
TI - SUMO Wrestles with Recombination
JF - Biomolecules
VL - 2
IS - 3
SP - 350-375
EP - 350-375
PB - MDPI AG
SN - 2218273X
KW - SUMO homologous recombination
UR - http://www.mdpi.com/2218-273X/2/3/350
L2 - http://www.mdpi.com/2218-273X/2/3/350
N2 - DNA double-strand breaks (DSBs) comprise one of the most toxic DNA lesions, as the failure to repair a single DSB has detrimental consequences on the cell. Homologous recombination (HR) constitutes an error-free repair pathway for the repair of DSBs. On the other hand, when uncontrolled, HR can lead to genome rearrangements and needs to be tightly regulated. In recent years, several proteins involved in different steps of HR have been shown to undergo modification by small ubiquitin-like modifier (SUMO) peptide and it has been suggested that deficient sumoylation impairs the progression of HR. This review addresses specific effects of sumoylation on the properties of various HR proteins and describes its importance for the homeostasis of DNA repetitive sequences. The article further illustrates the role of sumoylation in meiotic recombination and the interplay between SUMO and other post-translational modifications.
ER -
ALTMANNOVÁ, Veronika, Peter KOLESÁR a Lumír KREJČÍ. SUMO Wrestles with Recombination. Online. \textit{Biomolecules}. Basel, Switzerland: MDPI AG, 2012, roč.~2, č.~3, s.~350-375. ISSN~2218-273X. Dostupné z: https://dx.doi.org/10.3390/biom2030350. [citováno 2024-04-24]
|
