KOPECKÁ, Marie, Susumu KAWAMOTO and Masashi YAMAGUCHI. A new F-actin structure in fungi: actin ring formation around the cell nucleus of Cryptococcus neoformans. Journal of Electron Microscopy. OXFORD: OXFORD UNIV PRESS, 2013, vol. 62, No 2, p. 295-301. ISSN 0022-0744. doi:10.1093/jmicro/dfs074.
Other formats:   BibTeX LaTeX RIS
Basic information
Original name A new F-actin structure in fungi: actin ring formation around the cell nucleus of Cryptococcus neoformans
Authors KOPECKÁ, Marie (203 Czech Republic, guarantor, belonging to the institution), Susumu KAWAMOTO (392 Japan) and Masashi YAMAGUCHI (392 Japan).
Edition Journal of Electron Microscopy, OXFORD, OXFORD UNIV PRESS, 2013, 0022-0744.
Other information
Original language English
Type of outcome Article in a journal
Field of Study Genetics and molecular biology
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 1.632
RIV identification code RIV/00216224:14110/13:00065948
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1093/jmicro/dfs074
UT WoS 000317506600006
Keywords in English perinuclear F-actin ring; nucleus; Cryptococcus neoformans
Tags International impact, Reviewed
Changed by Changed by: Ing. Mgr. Věra Pospíšilíková, učo 9005. Changed: 24. 5. 2013 14:36.
Abstract
The F-actin cytoskeleton of Cryptococcus neoformans is known to comprise actin cables, cortical patches and cytokinetic ring. Here, we describe a new F-actin structure in fungi, a perinuclear F-actin collar ring around the cell nucleus, by fluorescent microscopic imaging of rhodamine phalloidin-stained F-actin. Perinuclear F-actin rings form in Cryptococcus neoformans treated with the microtubule inhibitor Nocodazole or with the drug solvent dimethyl sulfoxide (DMSO) or grown in yeast extract peptone dextrose (YEPD) medium, but they are absent in cells treated with Latrunculin A. Perinuclear F-actin rings may function as ‘funicular cabin’ for the cell nucleus, and actin cables as intracellular ‘funicular’ suspending nucleus in the central position in the cell and moving nucleus along the polarity axis along actin cables.
Links
GA310/06/0605, research and development projectName: Lidské patogenní houby : cytoskelet jako potenciální terč inhibice morfogeneze.
Investor: Czech Science Foundation, Human pathogenic fungi: the cytoskeleton as a potential target of inhibition of
PrintDisplayed: 1. 7. 2022 04:49