SLABÝ, Ondřej, Marek SVOBODA, Renata HÉŽOVÁ and Martina RÉDOVÁ. 3rd ICCTI Workshop - MicroRNAs in Oncology. 2012.
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Basic information
Original name 3rd ICCTI Workshop - MicroRNAs in Oncology
Authors SLABÝ, Ondřej, Marek SVOBODA, Renata HÉŽOVÁ and Martina RÉDOVÁ.
Edition 2012.
Other information
Original language English
Type of outcome Organization of a workshop
Field of Study 30200 3.2 Clinical medicine
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Organization unit Central European Institute of Technology
Keywords in English microRNAs; oncology
Changed by Changed by: Mgr. Petra Vychytilová, Ph.D., učo 211789. Changed: 5/12/2012 10:00.
Abstract
MicroRNAs (miRNAs) are small non-coding RNAs 18-25 nucleotides in length that downregulate gene expression during various crucial cell processes such as apoptosis, differentiation and developmnet. Changes in the expression profiles of miRNAs have been observed in a variety of human solidtumors and hametological malignancies. Functional studies indicate that miRNAs act as tumor suppressors and oncogenes. These findings significantly extend concept of molecular pathogenesis of cancer and have shown great potential for miRNA as a novel class of therapeutic targets.
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