D ASCENZO, Fabrizio, Erika CAVALLERO, Claudio MORETTI, Pierluigi OMEDE, Filippo SCIUTO, Ishtiaq A. RAHMAN, Robert S. BONSER, Jeon YUNSEOK, Robert WAGNER, Tomáš FREIBERGER, Gudrun KUNST, Michael S. MARBER, Matthias THIELMANN, Bingyang JI, Yasser M. AMR, Maria Grazia MODENA, Giuseppe Biondi ZOCCAI, Imad SHEIBAN a Fiorenzo GAITA. Remote ischaemic preconditioning in coronary artery bypass surgery: a meta-analysis. Heart. London: BMJ Publishing Group, roč. 98, č. 17, s. 1267-1271. ISSN 1355-6037. doi:10.1136/heartjnl-2011-301551. 2012. |
Další formáty:
BibTeX
LaTeX
RIS
@article{1076231, author = {D Ascenzo, Fabrizio and Cavallero, Erika and Moretti, Claudio and Omede, Pierluigi and Sciuto, Filippo and Rahman, Ishtiaq A. and Bonser, Robert S. and Yunseok, Jeon and Wagner, Robert and Freiberger, Tomáš and Kunst, Gudrun and Marber, Michael S. and Thielmann, Matthias and Ji, Bingyang and Amr, Yasser M. and Modena, Maria Grazia and Zoccai, Giuseppe Biondi and Sheiban, Imad and Gaita, Fiorenzo}, article_location = {London}, article_number = {17}, doi = {http://dx.doi.org/10.1136/heartjnl-2011-301551}, keywords = {RANDOMIZED CONTROLLED-TRIAL; CARDIAC TROPONIN-I; GRAFT-SURGERY; REPERFUSION INJURY; MYOCARDIAL PROTECTION; CARDIOPROTECTION; ISOFLURANE; STRATEGIES; STATEMENT; HUMANS}, language = {eng}, issn = {1355-6037}, journal = {Heart}, title = {Remote ischaemic preconditioning in coronary artery bypass surgery: a meta-analysis}, url = {http://heart.bmj.com/content/98/17/1267}, volume = {98}, year = {2012} }
TY - JOUR ID - 1076231 AU - D Ascenzo, Fabrizio - Cavallero, Erika - Moretti, Claudio - Omede, Pierluigi - Sciuto, Filippo - Rahman, Ishtiaq A. - Bonser, Robert S. - Yunseok, Jeon - Wagner, Robert - Freiberger, Tomáš - Kunst, Gudrun - Marber, Michael S. - Thielmann, Matthias - Ji, Bingyang - Amr, Yasser M. - Modena, Maria Grazia - Zoccai, Giuseppe Biondi - Sheiban, Imad - Gaita, Fiorenzo PY - 2012 TI - Remote ischaemic preconditioning in coronary artery bypass surgery: a meta-analysis JF - Heart VL - 98 IS - 17 SP - 1267-1271 EP - 1267-1271 PB - BMJ Publishing Group SN - 13556037 KW - RANDOMIZED CONTROLLED-TRIAL KW - CARDIAC TROPONIN-I KW - GRAFT-SURGERY KW - REPERFUSION INJURY KW - MYOCARDIAL PROTECTION KW - CARDIOPROTECTION KW - ISOFLURANE KW - STRATEGIES KW - STATEMENT KW - HUMANS UR - http://heart.bmj.com/content/98/17/1267 L2 - http://heart.bmj.com/content/98/17/1267 N2 - Aim Randomised trials exploring remote ischaemic preconditioning (RIPC) in patients undergoing coronary artery bypass graft (CABG) surgery have yielded conflicting data regarding potential cardiovascular and renal protection, and are individually flawed by small sample size. Methods Three investigators independently searched the MEDLINE, EMBASE and Cochrane databases to identify randomised trials testing RIPC in patients undergoing CABG. Results Nine studies with 704 patients were included. Standardised mean difference of troponin I and T release showed a significant decrease (-0.36 (95% CI -0.62 to -0.09)). This difference held true after excluding the trials with cross-clamp fibrillation, the study with off-pump CABG and studies using a flurane as anaesthetic agent (-0.41 (95% CI -0.69 to -0.12), -0.38 (95% CI -0.70 to -0.07) and -0.37 (95% CI -0.63 to -0.12), respectively). A similar trend was also obtained for patients with multivessel disease (-0.41 (95% CI -0.73 to -0.08)). The trials evaluating postoperative creatinine reported a non-significant reduction (0.02 (95% CI -0.09 to 0.13)). Moreover, the length of in-hospital stay was not influenced by the kind of treatment (weighted mean difference 0.27 (95% CI -0.24 to 0.79)). Conclusion RIPC reduced the release of troponin in patients undergoing CABG. Larger randomised trials are needed to clarify the presence of a causal relationship between RIPC-induced troponin release and clinical adverse events. ER -
D ASCENZO, Fabrizio, Erika CAVALLERO, Claudio MORETTI, Pierluigi OMEDE, Filippo SCIUTO, Ishtiaq A. RAHMAN, Robert S. BONSER, Jeon YUNSEOK, Robert WAGNER, Tomáš FREIBERGER, Gudrun KUNST, Michael S. MARBER, Matthias THIELMANN, Bingyang JI, Yasser M. AMR, Maria Grazia MODENA, Giuseppe Biondi ZOCCAI, Imad SHEIBAN a Fiorenzo GAITA. Remote ischaemic preconditioning in coronary artery bypass surgery: a meta-analysis. \textit{Heart}. London: BMJ Publishing Group, roč.~98, č.~17, s.~1267-1271. ISSN~1355-6037. doi:10.1136/heartjnl-2011-301551. 2012.
|