GESCHEIDT, Tomáš, Kristína CZEKÓOVÁ, Tomáš URBÁNEK, Radek MAREČEK, Michal MIKL, Radka KUBÍKOVÁ, Sabina TELECKÁ, Hana ANDRLOVÁ, Ivica HUSÁROVÁ and Martin BAREŠ. Iowa Gambling Task in patients with early-onset Parkinson's disease: strategy analysis. NEUROLOGICAL SCIENCES. New York: Springer, 2012, vol. 33, No 6, p. 1329-1335. ISSN 1590-1874. Available from: https://dx.doi.org/10.1007/s10072-012-1086-x.
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Basic information
Original name Iowa Gambling Task in patients with early-onset Parkinson's disease: strategy analysis
Authors GESCHEIDT, Tomáš (203 Czech Republic, belonging to the institution), Kristína CZEKÓOVÁ (703 Slovakia, belonging to the institution), Tomáš URBÁNEK (203 Czech Republic), Radek MAREČEK (203 Czech Republic, belonging to the institution), Michal MIKL (203 Czech Republic, belonging to the institution), Radka KUBÍKOVÁ (203 Czech Republic, belonging to the institution), Sabina TELECKÁ (203 Czech Republic, belonging to the institution), Hana ANDRLOVÁ (703 Slovakia, belonging to the institution), Ivica HUSÁROVÁ (703 Slovakia, belonging to the institution) and Martin BAREŠ (203 Czech Republic, guarantor, belonging to the institution).
Edition NEUROLOGICAL SCIENCES, New York, Springer, 2012, 1590-1874.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30000 3. Medical and Health Sciences
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 1.412
RIV identification code RIV/00216224:14740/12:00062236
Organization unit Central European Institute of Technology
Doi http://dx.doi.org/10.1007/s10072-012-1086-x
UT WoS 000312131300014
Keywords in English Parkinson s disease; Iowa Gambling Task; Decision making; Executive function
Tags ok, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. et Mgr. Kristína Czekóová, Ph.D., učo 53006. Changed: 15/3/2018 10:15.
Abstract
The aim of our study was to analyse decision making in early-onset Parkinson's disease (PD) patients performing the Iowa Gambling Task (IGT). We compared 19 patients with early-onset PD (<45 years) on dopaminergic medication (no evidence of depression, dementia, executive dysfunction according to the Tower of London test and the Stroop test, or pathological gambling) with 20 age-matched controls. A computer version of the IGT was employed. The PD patients achieved slightly lower IGT scores than the control group. A detailed analysis based on 'shift frequencies' between the individual decks showed that the patients tended to change their preferences for the decks more frequently, with a higher preference for the 'disadvantageous' deck B. Control subjects seemed to develop a more effective strategy. These differences could be caused by the poorer ability of the patients to develop any strategy at all. We observed changes in decision making during IGT performance in patients with early-onset PD, although they had no executive dysfunction as measured by established neuropsychological tests. The more detailed analysis employed in the present study could lead to a more accurate study of IGT performance and application of IGT in clinical practice.
Links
ED1.1.00/02.0068, research and development projectName: CEITEC - central european institute of technology
MSM0021622404, plan (intention)Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS
Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.
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