TRNA, Jan, Petr DÍTĚ, Arona ADAMCOVÁ, Brianna J CRAWFORD a Markéta HERMANOVÁ. Diabetes Mellitus in Pancreatic Cancer Patients in the Czech Republic: Sex Differences. EXPERIMENTAL DIABETES RESEARCH. NEW YORK: HINDAWI PUBLISHING CORPORATION, Neuveden, červen, s. "nestrankovano", 5 s. ISSN 1687-5214. doi:10.1155/2012/414893. 2012.
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Základní údaje
Originální název Diabetes Mellitus in Pancreatic Cancer Patients in the Czech Republic: Sex Differences
Autoři TRNA, Jan (203 Česká republika, garant, domácí), Petr DÍTĚ (203 Česká republika, domácí), Arona ADAMCOVÁ (203 Česká republika, domácí), Brianna J CRAWFORD (840 Spojené státy) a Markéta HERMANOVÁ (203 Česká republika, domácí).
Vydání EXPERIMENTAL DIABETES RESEARCH, NEW YORK, HINDAWI PUBLISHING CORPORATION, 2012, 1687-5214.
Další údaje
Originální jazyk angličtina
Typ výsledku Článek v odborném periodiku
Obor 30000 3. Medical and Health Sciences
Stát vydavatele Spojené státy
Utajení není předmětem státního či obchodního tajemství
Impakt faktor Impact factor: 1.893
Kód RIV RIV/00216224:14110/12:00062710
Organizační jednotka Lékařská fakulta
Doi http://dx.doi.org/10.1155/2012/414893
UT WoS 000307570100001
Klíčová slova anglicky CLINICAL-DIAGNOSIS; RISK-FACTORS; CT SCANS; PREVALENCE; POPULATION; COHORT; ONSET; METAANALYSIS; MUTATIONS; MORTALITY
Příznaky Mezinárodní význam
Změnil Změnil: Mgr. Michal Petr, učo 65024. Změněno: 11. 1. 2013 14:52.
Anotace
Aims. The prevalence of diabetes mellitus in pancreatic cancer patients and control subjects was compared. Methods. Retrospective evaluation of 182 pancreatic cancer patients and 135 controls. The presence of diabetes was evaluated and the time period between the diagnosis of diabetes and pancreatic cancer was assessed. A subanalysis based on patient sex was conducted. Results. Diabetes mellitus was present in 64 patients (35.2%) in pancreatic cancer group and in 27 patients (20.0%) in control group (chi(2) = 8.709; P = 0.003). In 18 patients (28.1% of diabetic pancreatic cancer patients) diabetes was new-onset. Diabetes was new-onset in 23.3% of females compared to 38.1% of males (chi(2) = 1.537; P = 0.215). The overall prevalence of diabetes was significantly higher among female pancreatic cancer patients (25% versus 43.9%; chi(2) = 7.070, P = 0.008), while diabetes prevalence was equally represented in the control group patients (22.1% versus 17.2%;.2 = 0.484, P = 0.487). Conclusion. The prevalence of diabetes mellitus in study group of pancreatic cancer patients was significantly higher when compared to control group. Pancreatic cancer patients with diabetes were predominantly females, while diabetes was equally prevalent among sexes in the control group. Therefore, patient sex may play important role in the risk stratification.
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