ŠTOURAČ, Petr, Hana HARAZIM, Marta STODŮLKOVÁ, Martin HUSER, Ivo KŘIKAVA, Petr JANKŮ, Olga HAKLOVA, Lubomír HAKL, Roman ŠTOUDEK, Roman GÁL and Pavel ŠEVČÍK. Comparison of parturient – controlled remifentanil with epidural bupivacain and sufentanil for labour analgesia: Randomised controlled trial. Biomedical papers of the Medical Faculty of the University Palacký, Olomouc Czech Republic. Olomouc: Palacký University, 2014, vol. 158, No 2, p. 227-232. ISSN 1213-8118. doi:10.5507/bp.2012.073.
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Basic information
Original name Comparison of parturient – controlled remifentanil with epidural bupivacain and sufentanil for labour analgesia: Randomised controlled trial
Name in Czech Srovnání rodičkou řízeného podání remifentanilu s epidurální analgezií bupivakainem a sufentanilem u porodu: randomizovaná studie
Authors ŠTOURAČ, Petr (203 Czech Republic, guarantor, belonging to the institution), Hana HARAZIM (203 Czech Republic, belonging to the institution), Marta STODŮLKOVÁ (203 Czech Republic, belonging to the institution), Martin HUSER (203 Czech Republic, belonging to the institution), Ivo KŘIKAVA (203 Czech Republic, belonging to the institution), Petr JANKŮ (203 Czech Republic, belonging to the institution), Olga HAKLOVA (203 Czech Republic), Lubomír HAKL (203 Czech Republic, belonging to the institution), Roman ŠTOUDEK (203 Czech Republic, belonging to the institution), Roman GÁL (203 Czech Republic, belonging to the institution) and Pavel ŠEVČÍK (203 Czech Republic, belonging to the institution).
Edition Biomedical papers of the Medical Faculty of the University Palacký, Olomouc Czech Republic, Olomouc, Palacký University, 2014, 1213-8118.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30214 Obstetrics and gynaecology
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 1.200
RIV identification code RIV/00216224:14110/14:00074648
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.5507/bp.2012.073
UT WoS 000338628200011
Keywords (in Czech) porodní analgezie; epidurální analgezie; rodičkou řízená intravenózní analgezie; remifentanil
Keywords in English obstetric analgesia; epidural analgesia; parturient-controlled intravenous analgesia; remifentanil
Tags EL OK
Tags International impact, Reviewed
Changed by Changed by: Ing. Mgr. Věra Pospíšilíková, učo 9005. Changed: 8. 4. 2015 13:19.
Abstract
Epidural analgesia (EA) has significant contraindications including coagulation disorders and parturient refusal. One alternative is intravenous self-administered analgesia using the ultra short-acting opioid remifentanil (rPCA). We compared the efficiency and safety of standard epidural analgesia with parturient-controlled intravenous analgesia using remifentanil as well as personal satisfaction. We enrolled twelve ASA I classified women with singleton pregnancy who delivered vaginally in the period 3/2010-5/2010 and who received rPCA (n=12) in standard analgesic protocol: 20 mcg boluses using PCA pump with a lockout interval of 3 min. The control group consisted of 12 pregnant women who received EA (n=12): 0.125% bupivacaine with sufentanil 0.5 mcg/mL in top-up boluses every hour until delivery. Data were acquired from standard Acute Pain Service (APS) form and patient medical records (demographic, labour course parameters), Visual Analogue Scale (VAS), Bromage Scale (BS) and adverse effects of analgesia. There were no demographic or labour course parameter differences between groups (P>0.05). The differences in VAS decrease (P=0.056) and parturient satisfaction (P=0.24) during the whole analgesia administration were statistically insignificant. The main limitation of the study was small sample and enrolment of healthy singleton pregnant women only. Remifentanil use in obstetric analgesia is a viable alternative to EA, especially in cases of EA contraindications and parturient disapproval.
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