Comparison of parturient – controlled remifentanil with
epidural bupivacain  and sufentanil for labour analgesia:
Randomised controlled trial

J 2014

Comparison of parturient – controlled remifentanil with epidural bupivacain and sufentanil for labour analgesia: Randomised controlled trial

ŠTOURAČ, Petr, Hana HARAZIM, Marta STODŮLKOVÁ, Martin HUSER, Ivo KŘIKAVA et. al.

Basic information

Original name

Comparison of parturient – controlled remifentanil with epidural bupivacain and sufentanil for labour analgesia: Randomised controlled trial

Name in Czech

Srovnání rodičkou řízeného podání remifentanilu s epidurální analgezií bupivakainem a sufentanilem u porodu: randomizovaná studie

Authors

ŠTOURAČ, Petr (203 Czech Republic, guarantor, belonging to the institution), Hana HARAZIM (203 Czech Republic, belonging to the institution), Marta STODŮLKOVÁ (203 Czech Republic, belonging to the institution), Martin HUSER (203 Czech Republic, belonging to the institution), Ivo KŘIKAVA (203 Czech Republic, belonging to the institution), Petr JANKŮ (203 Czech Republic, belonging to the institution), Olga HAKLOVA (203 Czech Republic), Lubomír HAKL (203 Czech Republic, belonging to the institution), Roman ŠTOUDEK (203 Czech Republic, belonging to the institution), Roman GÁL (203 Czech Republic, belonging to the institution) and Pavel ŠEVČÍK (203 Czech Republic, belonging to the institution)

Edition

Biomedical papers of the Medical Faculty of the University Palacký, Olomouc Czech Republic, Olomouc, Palacký University, 2014, 1213-8118

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30214 Obstetrics and gynaecology

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 1.200

RIV identification code

RIV/00216224:14110/14:00074648

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.5507/bp.2012.073

UT WoS

000338628200011

Keywords (in Czech)

porodní analgezie; epidurální analgezie; rodičkou řízená intravenózní analgezie; remifentanil

Keywords in English

obstetric analgesia; epidural analgesia; parturient-controlled intravenous analgesia; remifentanil

Abstract

V originále

Epidural analgesia (EA) has significant contraindications including coagulation disorders and parturient refusal. One alternative is intravenous self-administered analgesia using the ultra short-acting opioid remifentanil (rPCA). We compared the efficiency and safety of standard epidural analgesia with parturient-controlled intravenous analgesia using remifentanil as well as personal satisfaction. We enrolled twelve ASA I classified women with singleton pregnancy who delivered vaginally in the period 3/2010-5/2010 and who received rPCA (n=12) in standard analgesic protocol: 20 mcg boluses using PCA pump with a lockout interval of 3 min. The control group consisted of 12 pregnant women who received EA (n=12): 0.125% bupivacaine with sufentanil 0.5 mcg/mL in top-up boluses every hour until delivery. Data were acquired from standard Acute Pain Service (APS) form and patient medical records (demographic, labour course parameters), Visual Analogue Scale (VAS), Bromage Scale (BS) and adverse effects of analgesia. There were no demographic or labour course parameter differences between groups (P>0.05). The differences in VAS decrease (P=0.056) and parturient satisfaction (P=0.24) during the whole analgesia administration were statistically insignificant. The main limitation of the study was small sample and enrolment of healthy singleton pregnant women only. Remifentanil use in obstetric analgesia is a viable alternative to EA, especially in cases of EA contraindications and parturient disapproval.

Files attached

Comparison_of_parturient.pdf

Request the author's version of the file

Citovat

ŠTOURAČ, Petr, Hana HARAZIM, Marta STODŮLKOVÁ, Martin HUSER, Ivo KŘIKAVA, Petr JANKŮ, Olga HAKLOVA, Lubomír HAKL, Roman ŠTOUDEK, Roman GÁL and Pavel ŠEVČÍK. Comparison of parturient – controlled remifentanil with epidural bupivacain and sufentanil for labour analgesia: Randomised controlled trial. Biomedical papers of the Medical Faculty of the University Palacký, Olomouc Czech Republic. Olomouc: Palacký University, 2014, vol. 158, No 2, p. 227-232. ISSN 1213-8118. Available from: https://dx.doi.org/10.5507/bp.2012.073.

@article{1081519,
   author = {Štourač, Petr and Harazim, Hana and Stodůlková, Marta and Huser, Martin and Křikava, Ivo and Janků, Petr and Haklova, Olga and Hakl, Lubomír and Štoudek, Roman and Gál, Roman and Ševčík, Pavel},
   article_location = {Olomouc},
   article_number = {2},
   doi = {http://dx.doi.org/10.5507/bp.2012.073},
   keywords = {obstetric analgesia; epidural analgesia; parturient-controlled intravenous analgesia; remifentanil},
   language = {eng},
   issn = {1213-8118},
   journal = {Biomedical papers of the Medical Faculty of the University Palacký, Olomouc Czech Republic},
   title = {Comparison of parturient – controlled remifentanil with epidural bupivacain and sufentanil for labour analgesia: Randomised controlled trial},
   url = {http://biomed.papers.upol.cz/pdfs/bio/2014/02/11.pdf},
   volume = {158},
   year = {2014}
}

TY  - JOUR
ID  - 1081519
AU  - Štourač, Petr - Harazim, Hana - Stodůlková, Marta - Huser, Martin - Křikava, Ivo - Janků, Petr - Haklova, Olga - Hakl, Lubomír - Štoudek, Roman - Gál, Roman - Ševčík, Pavel
PY  - 2014
TI  - Comparison of parturient – controlled remifentanil with epidural bupivacain and sufentanil for labour analgesia: Randomised controlled trial
JF  - Biomedical papers of the Medical Faculty of the University Palacký, Olomouc Czech Republic
VL  - 158
IS  - 2
SP  - 227-232
EP  - 227-232
PB  - Palacký University
SN  - 12138118
KW  - obstetric analgesia
KW  - epidural analgesia
KW  - parturient-controlled intravenous analgesia
KW  - remifentanil
UR  - http://biomed.papers.upol.cz/pdfs/bio/2014/02/11.pdf
N2  - Epidural analgesia (EA) has significant contraindications including coagulation disorders and parturient refusal. One alternative is intravenous self-administered analgesia using the ultra short-acting opioid remifentanil (rPCA). We compared the efficiency and safety of standard epidural analgesia with parturient-controlled intravenous analgesia using remifentanil as well as personal satisfaction. We enrolled twelve ASA I classified women with singleton pregnancy who delivered vaginally in the period 3/2010-5/2010 and who received rPCA (n=12) in standard analgesic protocol: 20 mcg boluses using PCA pump with a lockout interval of 3 min. The control group consisted of 12 pregnant women who received EA (n=12): 0.125% bupivacaine with sufentanil 0.5 mcg/mL in top-up boluses every hour until delivery. Data were acquired from standard Acute Pain Service (APS) form and patient medical records (demographic, labour course parameters), Visual Analogue Scale (VAS), Bromage Scale (BS) and adverse effects of analgesia. There were no demographic or labour course parameter differences between groups (P>0.05). The differences in VAS decrease (P=0.056) and parturient satisfaction (P=0.24) during the whole analgesia administration were statistically insignificant. The main limitation of the study was small sample and enrolment of healthy singleton pregnant women only. Remifentanil use in obstetric analgesia is a viable alternative to EA, especially in cases of EA contraindications and parturient disapproval.
ER  -

ŠTOURAČ, Petr, Hana HARAZIM, Marta STODŮLKOVÁ, Martin HUSER, Ivo KŘIKAVA, Petr JANKŮ, Olga HAKLOVA, Lubomír HAKL, Roman ŠTOUDEK, Roman GÁL and Pavel ŠEVČÍK. Comparison of parturient – controlled remifentanil with epidural bupivacain and sufentanil for labour analgesia: Randomised controlled trial. \textit{Biomedical papers of the Medical Faculty of the University Palacký, Olomouc Czech Republic}. Olomouc: Palacký University, 2014, vol.~158, No~2, p.~227-232. ISSN~1213-8118. Available from: https://dx.doi.org/10.5507/bp.2012.073.

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