J 2012

Urinary calculi – atypical source of information on mercury in human biomonitoring.

KUTA, Jan, Jiří MACHÁT, Daniela BENOVÁ, Rostislav ČERVENKA, Tamara KOŘISTKOVÁ et. al.

Basic information

Original name

Urinary calculi – atypical source of information on mercury in human biomonitoring.

Authors

KUTA, Jan (203 Czech Republic, guarantor, belonging to the institution), Jiří MACHÁT (203 Czech Republic, belonging to the institution), Daniela BENOVÁ (703 Slovakia, belonging to the institution), Rostislav ČERVENKA (203 Czech Republic, belonging to the institution) and Tamara KOŘISTKOVÁ (203 Czech Republic)

Edition

Central European Journal of Chemistry, WARSAW, POLAND, VERSITA, 2012, 1895-1066

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30304 Public and environmental health

Country of publisher

Poland

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 1.167

RIV identification code

RIV/00216224:14310/12:00058142

Organization unit

Faculty of Science

UT WoS

000306695700009

Keywords in English

Urolithiasis; Calculi; Mercury; Biomonitoring; Trace elements

Tags

Změněno: 11/4/2013 21:24, Ing. Andrea Mikešková

Abstract

V originále

Chemical analysis of various biological matrices is routinely used for assessment of human exposure to various toxic metals. In this work, 489 samples of urinary calculi originating from almost the whole of The Czech Republic, were collected and subjected to mineralogical and elemental analysis. This study was aimed at mercury, the content of which was determined using thermo-oxidation - cold vapor - atomic absorption spectrometry. The effects of mineralogical composition, sex, age and region were recorded in order to verify the applicability of urinary calculi for biomonitoring. Relationships with other minor and trace elements were also investigated. Association of mercury with whewellite mineral was observed as well as a remarkable relationship with selenium, confirming the role of selenium in mercury excretion. No statistically significant effect was observed on the mercury content in stones with regard to the sex or region. Median values in age groups follow a trend with the maximum median value 0.365 mg kg(-1) in the group of 41-50 year old donors, decreasing to 0.060 mg kg(-1) for the oldest group (81-92 years). Our results confirm that urinary calculi can be helpful in providing complementary information on human exposure to mercury and its excretion.

Links

ED0001/01/01, research and development project
Name: CETOCOEN
GA203/09/1394, research and development project
Name: Chemická, mineralogická a statistická analýza souboru močových konkrementů pacientů ostravské aglomerace
Investor: Czech Science Foundation, Chemical, mineralogical and statistical analysis of set of urinary stones of patients of Ostrava city aglomeration